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Found 144 clinical trials
Ocrelizumab or Alemtuzumab Compared With Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis - a Phase-2 Randomised Controlled Trial

A multicentre controlled phase II trial to compare the efficacy and safety of ocrelizumab or alemtuzumab and autologous Hematopoietic Stem Cell Transplantation (aHSCT). Active relapsing

ocrelizumab
alemtuzumab
disease or disorder
  • 0 views
  • 10 Oct, 2021
  • 2 locations
Autologous Hematopoietic Stem Cell Transplantation Combined With CAR-T Cells in the Treatment of Refractory and Relapsed Malignant Lymphoma

Clinical Study on the Safety and Effectiveness of Autologous Hematopoietic Stem Cell Transplantation Combined With CAR-T Cells in the Treatment of Refractory and Relapsed Malignant Lymphoma

cell transplantation
chronic lymphocytic leukemia
granulocyte colony stimulating factor
follicular lymphoma
filgrastim
  • 0 views
  • 24 Mar, 2022
  • 1 location
Using Romiplostim to Treat Low Platelet Counts Following Chemotherapy and Autologous Hematopoietic Cell Transplantation in People With Blood Cancer

addition, the researchers will determine how safe it is to give romiplostim to people with blood cancer who have received treatment with chemotherapy and autologous hematopoietic cell transplantation.

cell transplantation
platelet count
multiple myeloma
cancer
melphalan
  • 35 views
  • 11 Mar, 2022
  • 7 locations
Uproleselan (GMI-1271) for GI Toxicity Prophylaxis During Melphalan-Conditioned Autologous Hematopoietic Cell Transplantation (Auto-HCT) for Multiple Myeloma (MM)

The investigators hypothesize that prophylactic E-selectin inhibition via administration of uproleselan during melphalan conditioning will reduce the gastrointestinal (GI) toxicity in multiple myeloma (MM) patients undergoing auto-transplant, as assessed via diarrhea severity scoring per CTCAE v5.0, while potentially increasing chemosensitivity of malignant MM cells to high-dose melphalan.

cell transplantation
white blood cells
carbon monoxide
neutrophil count
melphalan
  • 0 views
  • 27 Apr, 2022
  • 1 location
The Effect of Breathing Exercise on Chemotherapy-induced Nausea and Vomiting in With Autologous Hematopoietic Stem Cell Transplantation Patients

vomiting. The aim of this study is to determine the effect of respiratory exercise on chemotherapy-induced nausea and vomiting in patients with autologous hematopoietic stem cell transplantation

  • 0 views
  • 30 Apr, 2022
  • 1 location
Study of Iberdomide in People With Multiple Myeloma Who Have Had an Autologous Hematopoietic Stem Cell Transplant (AHCT)

The purpose of this study is to see if iberdomide is a safe and effective maintenance therapy option for people with Multiple Myeloma (MM) who have had an Autologous Hematopoietic Stem Cell

platelet count
lenalidomide
neutrophil count
melphalan
cancer
  • 0 views
  • 27 Jun, 2022
  • 6 locations
A Study of Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab for Patients With Relapsed/Refractory Myeloma With Salvage Autologous Hematopoietic Cell Transplantation

The purpose of this study is to test any good and bad effects of giving a combination of study drugs before and after autologous stem cell transplant.

cell transplantation
immunomodulatory imide drug
treatment of hypercalcemia
measurable disease
carfilzomib
  • 1 views
  • 27 May, 2022
  • 10 locations
A Study of the Effects of AB-205 in Patients With Lymphoma Undergoing Autologous Hematopoietic Cell Transplantation (E-CELERATE)

High-dose chemotherapy followed by blood stem cell transplantation is administered to lymphoma patients with an intention to cure. However, high-dose chemotherapy simultaneously causes damage to healthy tissues that frequently result in severe complications that lead to hospitalization and can be life threatening. These severe complications involve the blood, immune, gastro-intestinal …

cell transplantation
high dose chemotherapy
melphalan
bendamustine
etoposide
  • 0 views
  • 26 May, 2022
  • 5 locations
Study of Plinabulin and Pegfilgrastim in People With Multiple Myeloma Undergoing an Autologous Hematopoietic Stem Cell Transplant (AHCT)

hematopoietic stem cell transplant (AHCT).

platelet count
human chorionic gonadotropin
stem cell infusion
melphalan
  • 0 views
  • 30 Jun, 2022
  • 7 locations
The Efficacy of Bendamustine, Gemcytabine, Dexamethasone Salvage Chemotherapy With Autologous Stem Cell Transplantation (BURGUND) Consolidation in Advanced Classical Hodgkin Lymphoma Patients Not Responding to ABVD Therapy (BURGUND)

The objective of the study is evaluation of efficacy of Bendamustine, Gemcytabine, Dexamethasone (BGD) salvage therapy with autologus stem cell transplantation (ASCT) consolidation in advanced classical Hodgkin lymphoma patients not responding to ABVD therapy.

cell transplantation
lymphoma
chemotherapy regimen
bendamustine
classical hodgkin lymphoma
  • 2 views
  • 25 Mar, 2022
  • 13 locations