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Found 144 clinical trials
Myeloma-Developing Regimens Using Genomics (MyDRUG) (MyDRUG)

The MyDRUG study is a type of Precision Medicine trial to treat patients with drugs targeted to affect specific genes that are mutated as part of the disease. Mutations in genes can lead to uncontrolled cell growth and cancer. Patients with a greater than 25% mutation to any of the …

  • 18 views
  • 07 Feb, 2022
  • 13 locations
Efficacy and Safety of Rituximab Plus Zanubrutinib and Lenalidomide for Relapsed and Refractory Diffuse Large B Cell Lymphoma, a Multicenter, Open and Prospective Clinical Trial

This clinical trial is an investigator-initiated multicenter, open, prospective clinical study in order to explore the efficacy and safety of rituximab plus zanubrutinib and lenalidomide in relapsed and refractory diffuse large B cell lymphoma.

  • 0 views
  • 07 Jun, 2022
  • 1 location
First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1)

The HL-Russia-1 is a non-randomized, open-label, multicenter, phase III, 3-arm study. The primary objective is to assess efficacy, safety and progression-free survival (PFS) of different approaches (earle favorable, early unfavorable and advanced stages) to first line chemotherapy for classical Hodgkin Lymphoma (HL).

  • 0 views
  • 27 Jan, 2021
  • 1 location
Rituximab and Lenalidomide vs Rituximab Alone as Maintenance After R-chemoterapy for Relapsed/Refractory FL Patients (FIL_RENOIR12)

A randomized phase III multicenter trial assessing efficacy and toxicity of a combination of Rituximab and Lenalidomide (R2) vs Rituximab alone as maintenance after chemoimmunotherapy with Rituximab-chemotherapy (R-CHT) for relapsed/refractory FL patients not eligible for autologous transplantation (ASCT)

bendamustine
neutrophil count
platelet count
rituximab
lenalidomide
  • 55 views
  • 23 Mar, 2022
  • 28 locations
Isa-KRd vs KRd in Newly Diagnosed Multiple Myeloma Patients Eligible for Autologous Stem Cell Transplantation (IsKia TRIAL)

This protocol is a phase III study designed to compare the efficacy and the safety of Isa-KRd induction, transplant, Isa-KRd post ASCT consolidation and Isa-KRd light consolidation vs KRd induction, transplant, KRd post ASCT consolidation and KRd light consolidation After confirmation of eligibility criteria patients will be randomized to one …

  • 0 views
  • 27 Jan, 2021
  • 7 locations
Health Information Technology System ("Roadmap 2.0") in the Context of Hematopoietic Cell Transplantation

/autologous hematopoietic cell transplantation (HCT).

cell transplantation
  • 0 views
  • 25 Mar, 2022
  • 2 locations
Platelet Transfusions in Hematopoietic Stem Cell Transplantation (The PATH Trial) (PATH)

platelet transfusions in patients undergoing an autologous hematopoietic stem cell transplantation (ASCT).

cell transplantation
tranexamic acid
hematologic malignancy
  • 0 views
  • 22 Mar, 2022
  • 3 locations
Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients (DALY 2-EU)

/refractory diffuse large B-cell lymphoma, who are not eligible for high-dose chemotherapy and autologous stem cell transplantation.

  • 1 views
  • 28 Jun, 2022
  • 35 locations
Self-Management Program and Survivorship Care Plan in Improving the Health of Cancer Survivors After Stem Cell Transplant (INSPIRE)

This phase III trial investigates health informatics and a self-management program for improving the health of cancer survivors after stem cell transplant. After transplant many survivors may feel stressed or may be unsure of what health care they need. A self-management program called "INSPIRE," along with a personalized survivorship care …

remission
cancer
  • 73 views
  • 15 Jun, 2022
  • 12 locations
177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-risk Neuroblastoma

strategy requires a readiness for autologous stem cell transplantation in all patients, but is not anticipated to increase the risk of long-term sequelae, since the cumulative radiation dose remains

high-risk neuroblastoma
somatostatin
neutrophil count
68ga-dotatoc
  • 0 views
  • 05 Jun, 2021
  • 6 locations