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Found 9 clinical trials
Hearing Speech in Noise

The purpose of the study is to learn more about how people process speech. There is 1 study visit that will last about 1 hour. Participation includes an audiogram, a word-in-noise identification

  • 11 Feb, 2019
  • 1 location
Intranasal Dexmedetomidine for Sedated Hearing Testing

Auditory brainstem response testing is necessary in children who are not able to be tested by classical audiogram, because of their age or an associated retarded psycho-motor development or

  • 24 Jan, 2021
  • 2 locations
Iron Balance Study of Deferasirox Deferoxamine and the Combination of Both

Subjects with thalassemia major require regular transfusion therapy to sustain life. The iron present in the transfused blood remains in the body where it can cause a variety of organ dysfunctions. Lifelong iron chelation therapy is needed to maintain iron balance but its effectiveness varies greatly. Like that of deferoxamine …

iron overload
chelation therapy
  • 07 Nov, 2020
  • 1 location
Effect of Propfol Versus Sevoflurane on Auditory and Cognitive Function

a good estimate of the shape of the behavioral audiogram [and is thus an extremely useful tool for studying hearing sensitivity as well as the functionality of the auditory system. An

  • 02 Jun, 2021
  • 1 location
An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus

This is an exploratory pilot open-label study to identify the signal changes on fMRI of patients with tinnitus and with temporary suppression of the tinnitus with IV lidocaine. Patients will include those with hearing loss (both unilateral and bilateral) and tinnitus, subjects with normal hearing and tinnitus, and control subjects …

  • 09 May, 2021
  • 1 location
Optimization of a Non-invasive Electrophysiological Method for Studying the Functionality of Auditory Nerve Fibers

Acoustic overexposure can induced temporary or hearing loss. Usually hearing loss is associated with cochlear cell damages. Recently, a new pathological entity was described and called "hidden hearing loss". In animal model, the histopathology revealed a selective reduction in the number of auditory fibers, resulting in a decrease in the …

  • 23 Jan, 2021
  • 1 location
Chitogel CSK-4 Gel as Packing in Tympanoplasty Surgery

Little innovation in the material used for middle ear packing has occurred over the past decade, despite the fact that animal models have shown increased acute inflammation and increased fibrosis in the long term histologically. Although Chitosan Succinamide has shown improved wound healing and hemostasis in the nasal cavity mucosa, …

  • 14 Mar, 2021
  • 1 location
The SeaSHeL National Prospective Cohort Study

Each year, approximately 15,000 people in the United Kingdom experience sudden loss of hearing that is sensorineural in nature. In the majority of cases, the cause is unknown despite investigation, and these cases are termed idiopathic 'sudden onset sensorineural hearing loss' (SSNHL). Treatment options for idiopathic SSNHL mainly include steroid …

hard of hearing
  • 24 Jan, 2021
  • 1 location
Enlarged Vestibular Aqueduct Registry

People with the congenital anatomical malformation known as "Enlarged Vestibular Aqueduct" (EVA) may experience decline in hearing ability. This is an online registry to gather patient experiences with EVA, with the goal of providing future researchers with the information necessary to better evaluate and make recommendations for patients with EVA. …

  • 22 Jan, 2021
  • 2 locations