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Found 15 clinical trials
Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors (PNOC025)

macrophages and enhances tumor cell phagocytosis. Pre-clinical studies have shown that treatment with magrolimab leads to prolonged survival in models of Atypical Teratoid Rhabdoid Tumors (ATRT), diffuse

  • 0 views
  • 29 May, 2022
  • 1 location
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Approximately 90% of children with malignant brain tumors that have recurred or relapsed after receiving conventional therapy will die of disease. Despite this terrible and frustrating outcome, continued treatment of this population remains fundamental to improving cure rates. Studying this relapsed population will help unearth clues to why conventional therapy …

medulloblastoma
cancer
sonidegib
conventional treatment
brain tumor
  • 224 views
  • 19 Apr, 2022
  • 1 location
Study of Stored Tumor Samples in Young Patients With Brain Tumors

This laboratory study is looking at stored tumor samples in young patients with brain tumors. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

  • 3 views
  • 24 Apr, 2022
  • 1 location
Rare CNS Tumors Outcomes &Risk

, including: Atypical teratoid rhabdoid tumor (ATRT); Brainstem and midline gliomas; Choroid plexus tumors; Ependymoma; High grade meningioma; Gliomatosis cerebri; Medulloblastoma; Oligodendroglioma

primitive neuroectodermal tumor
oligodendroglioma, anaplastic
oligodendroglioma
medulloblastoma
ependymoma
  • 41 views
  • 19 Jun, 2022
  • 1 location
Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

Anaplastic Thyroid Cancer Angiosarcoma Atypical Teratoid Rhabdoid Tumor/MRT Carcinoid Carcinoma of Unknown Primary Chondrosarcoma

cancer
solid tumor
Accepts healthy volunteers
cns tumor
  • 36 views
  • 28 Jun, 2022
  • 1 location