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Found 807 clinical trials
Featured trial
Accelerated Genital Tract Aging in HIV: Estradiol Clinical Trial

of vaginal atrophy in menopausal women living with HIV. 

  • 77 views
  • 03 Mar, 2021
  • 1 location
Featured trial
Vaginal dryness

Vaginal dryness

  • 917 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Proteins and Brain Networks in Atypical Alzheimer's Disease

Participants will take part in 2-4 study visits including detailed history and neurological exam, pen-&-paper cognitive testing, and functional MRI and PET scans designed to help us understand how different forms of Alzheimer's disease affect brain circuits over time.

amyloid
positron emission tomography
Accepts healthy volunteers
  • 53 views
  • 24 Jan, 2022
  • 1 location
Featured trial
New Approaches to Dementia Heterogeneity.

This study is looking for adults who have mild cognitive impairment, Alzheimer’s, or other forms of dementia. The study is also looking for people with normal cognition, as a comparison. The study is interested in the ways that brain function changes over time with the goal of improving the ability to diagnose …

cognitive impairment
depression
vascular dementia
aphasia
dementia, frontotemporal
  • 149 views
  • 25 May, 2021
  • 1 location
Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy (DEVOTE)

The primary objectives of this study are to examine the clinical efficacy of nusinersen administered intrathecally at higher doses to participants with spinal muscular atrophy (SMA), as measured

gene deletion
muscle atrophy
nusinersen
  • 168 views
  • 02 May, 2022
  • 49 locations
A Study of Nusinersen Among Participants With Spinal Muscular Atrophy Who Received Onasemnogene Abeparvovec (RESPOND)

The primary objective of this study is to evaluate the clinical outcomes following treatment with nusinersen in participants with spinal muscular atrophy (SMA) who previously received

gene deletion
nusinersen
  • 2 views
  • 15 Mar, 2022
  • 17 locations
Study on Early Brain Injury Mechanism and Comprehensive Intervention of VCI

Alzheimer's disease (AD) and vascular dementia (VaD) are the most common forms of senile dementia. Although the animal research of dementia has made remarkable progress, clinical trials of drugs for AD pathology have failed in recent years. The study of dementia based on cell and animal model generally aims at …

  • 21 views
  • 19 Aug, 2021
  • 1 location
Efficacy in Alveolar Bone Regeneration With Autologous MSCs and Biomaterial in Comparison to Autologous Bone Grafting (Maxibone)

A randomized controlled clinical multi center trial to assess the efficacy of a combination of autologous mesenchymal stem cells and biomaterial in jaw bone regeneration prior to dental implant placement in comparison to standard autologous bone block grafting.

Accepts healthy volunteers
bone graft
dental implantation
  • 126 views
  • 28 Feb, 2022
  • 4 locations
Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

The objective of the study is to determine how controlled mode ventilation and support mode ventilation impact ventilator-free days and diaphragmatic atrophy.

  • 0 views
  • 08 May, 2021
  • 1 location
Enhanced Bioscaffold for Volumetric Muscle Loss (MTEC VML)

This is a prospective, single center study conducted at the University of Pittsburgh designed to test the applicability and utility of XenMatrix™ AB Surgical Graft in the restoration of function in the setting of volumetric muscle loss after soft tissue trauma.

  • 0 views
  • 27 Feb, 2022
  • 1 location