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Found 63 clinical trials
Mgt of Chronic Subdural Hematoma Using Dexamethasone

diuretics, Atorvastatin or Angiotensin converting enzyme (ACE) inhibitors. Corticosteroids may be a therapeutic option in the management of cSDH. There is very little data on the efficacy of

  • 7 views
  • 25 Jan, 2021
  • 1 location
Efficacy and Safety Of Alirocumab to Prevent Early Cardiac Allograft Vasculopathy in Recent Heart Transplant Recipients

efficacy and safety of alirocumab compared to placebo administered during the first year after transplantation in heart transplant recipients in addition to background atorvastatin therapy. Except lipid

  • 1 views
  • 21 Feb, 2021
  • 3 locations
Is Treatment of Vitamin D Deficiency Associated With Resolution of Statin-Induced Muscular Symptoms

Statins are a class of drugs that are highly effective at lowering cholesterol levels. However, compliance is often limited by symptoms of muscle pain. The investigators would like to study Vitamin-D deficient individuals who also have muscle pain due to statin use. About 1 billion people are estimated to have …

  • 10 views
  • 22 Jan, 2021
  • 1 location
Endothelial Function in Obstructive Sleep Apnea

Obstructive sleep apnea (OSA), a condition that affects a quarter of the Western adults, triples the risk for cardiovascular diseases and increases all-cause mortality. Intermittent hypoxia (IH) during transient cessation of breathing in OSA leads to endothelial inflammation, a key step in the initiation and progression of cardiovascular disease. However, …

  • 0 views
  • 22 Jan, 2021
  • 1 location
Pravastatin Therapy in Patients With Active Crohn's Disease: A Pilot Study

The primary objective of this study is to provide data regarding clinical and immunologic activity of oral doses of pravastatin 80mg administered daily for 6 consecutive weeks, for the treatment of active Crohn's disease as shown by the Harvey-Bradshaw Index (HBI) and/or elevated C-reactive protein (CRP). We hypothesize pravastatin will …

methotrexate
ciprofloxacin
prednisone
azathioprine
mesalamine
  • 21 views
  • 07 Nov, 2020
  • 1 location
Intensive Management of Blood Pressure and Cholesterol in Elderly Chinese With Hypertension and Atrial Fibrillation

Study name: Intensive management of blood pressure and cholesterol in elderly Chinese with hypertension and atrial fibrillation (IMPRESSION) Medicine: amlodipine/atorvastatin (5

blood pressure diastolic
atorvastatin
systolic blood pressure
fibrillation
hypertension
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Clinical Trial of STAtin Therapy for Reducing Events in the Elderly (STAREE)

The STAREE study will examine whether treatment with statin (atorvastatin 40mg) compared with placebo will prolong overall survival or disability free survival amongst healthy elderly people (70

  • 0 views
  • 23 Jan, 2021
  • 3 locations
Secondary Prevention of Cardiovascular Disease in the Elderly Trial

The purpose of this study is to evaluate the efficacy of a polypill strategy containing aspirin (100 mg), ramipril (2.5, 5 or 10 mgs), and atorvastatin (40 mgs) compared with the standard of

diabetes
myocardial infarction
infarct
revascularisation
coronary disease
  • 12 views
  • 23 Jan, 2021
  • 112 locations
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted

cognitive impairment
primary prevention
mild cognitive impairment
dementia
atorvastatin
  • 104 views
  • 26 Jan, 2021
  • 87 locations
The MASTER Study (MAmmary Cancer STatin ER Positive Study)

randomized, multicenter, double-blind, placebo-controlled comparison of standard (neo)adjuvant therapy plus placebo versus standard (neo)adjuvant therapy plus atorvastatin in patients with early breast

  • 0 views
  • 28 Jan, 2021
  • 1 location