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Found 22 clinical trials
Defining the Severe Paediatric Asthma Endotype

, combining a description of their phenotype (asthma symptoms, atopy, and lung function) associated with histological (airway inflammation and remodelling), immune (innate and adaptive immunity), metabolomics

  • 0 views
  • 29 Nov, 2021
  • 1 location
Tolerability of Goat Milk Protein in Eosinophilic Esophagitis Patients With Cow Milk Protein Trigger

cytokines, yet it may also be triggered by environmental allergens. In addition, the rates of atopy are approximately 3 times higher in patients with EoE than in the general population. Furthermore, and

  • 0 views
  • 22 Mar, 2022
  • 1 location
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation

investigation. This work is designed to identify airway factors that are responsible for recruiting cells and associate their airway presence with atopy and asthma.

obstruction
airway obstruction
skin prick test
Accepts healthy volunteers
allergen
  • 37 views
  • 20 Apr, 2022
  • 1 location
Tacrolimus Versus Hydrocortisone in Atopic Dermatitis

Atopic dermatitis (AD) is a very common inflammatory, genetic skin disorder that occurs more frequently in children. Its exact etiology is not known but it is characterized by pruritic skin reactions with elevation in the levels of inflammatory markers. Corticosteroids are the first line and the mainstay therapy in management …

  • 0 views
  • 27 Apr, 2022
Prevention of Dermatitis in Epoxy Exposed Workers

, 4 times during the 2 year follow up period. All participants are patch tested, screened for dermatitis and atopy at start and end of follow up or at end of employment. The investigators also

sensitization
Accepts healthy volunteers
triamcinolone acetonide ointment
  • 10 views
  • 04 Feb, 2022
  • 1 location
Safety and Efficacy of Fecal Microbiota Transplantation

, dysbiotic bowel syndrome, MRSA enteritis, Pseudomembranous enteritis, idiopathic thrombocytopenic purpura (ITP), and atopy. Despite FMT appears to be relatively safe and efficacious in treating a

purpura
fatty liver
constipation
MRSA
carbapenem
  • 427 views
  • 23 Mar, 2022
  • 1 location
Screening and Diagnosing Exercise-induced Bronchoconstriction in Recreational Young Athletes (12-18 y)

The purpose of this study is to validate the screening protocol to study risk factors of exercise-induced bronchoconstriction (EIB) obtained in our previous study in high-school elite athletes (NCT03587675), in recreational young athletes who perform intense physical exercise.

Accepts healthy volunteers
  • 0 views
  • 14 Nov, 2021
  • 1 location
Main Trial of the Cesarean Section and Intestinal Flora of the Newborn Study (MT-SECFLOR)

In this study the investigators assess whether, in CS-delivered infants, the intestinal microbiome could be successfully and safely normalised by postnatal oral transfer of maternal fecal microbiome.

Accepts healthy volunteers
  • 0 views
  • 19 Feb, 2022
  • 1 location
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing (INSTAR)

The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection. The secondary objectives are to determine duration and severity of each acute episode with acute expiratory breathing difficulty, the number of episodes …

corticosteroid therapy
steroid therapy
corticosteroids
wheezing
  • 34 views
  • 12 Feb, 2022
  • 8 locations
Evaluation of SUMMIT BRUSH in Treatment of Blepharitis

Dry Eye Disease (DED) is a multifactorial disease that affects ~15-30 million people in the USA alone. It creates an enormous societal and economic burden, decreases productivity in the workplace, and affects the quality of lives of the people affected by this disease. DED is primarily caused by blepharitis, a …

  • 13 views
  • 27 Jan, 2021
  • 3 locations