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Found 20 clinical trials
Defining the Severe Paediatric Asthma Endotype

, combining a description of their phenotype (asthma symptoms, atopy, and lung function) associated with histological (airway inflammation and remodelling), immune (innate and adaptive immunity), metabolomics

  • 0 views
  • 29 Nov, 2021
  • 1 location
Tolerability of Goat Milk Protein in Eosinophilic Esophagitis Patients With Cow Milk Protein Trigger

cytokines, yet it may also be triggered by environmental allergens. In addition, the rates of atopy are approximately 3 times higher in patients with EoE than in the general population. Furthermore, and

  • 0 views
  • 22 Mar, 2022
  • 1 location
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation

investigation. This work is designed to identify airway factors that are responsible for recruiting cells and associate their airway presence with atopy and asthma.

skin prick test
obstruction
allergen
Accepts healthy volunteers
atopy
  • 37 views
  • 20 Apr, 2022
  • 1 location
Omalizumab Before Onset of Exacerbations (OBOE)

OBOE is a prospective, pilot, parallel group RCT with the overall aim of examining the effect of a single dose of anti-IgE (omalizumab) vs. placebo administered at the onset of URIs in the fall season among highly exacerbation-prone, urban, and atopic youth aged 6-17 years with persistent asthma. OBOE will …

  • 0 views
  • 22 Sep, 2022
  • 1 location
Prevention of Dermatitis in Epoxy Exposed Workers

, 4 times during the 2 year follow up period. All participants are patch tested, screened for dermatitis and atopy at start and end of follow up or at end of employment. The investigators also

sensitization
Accepts healthy volunteers
triamcinolone acetonide ointment
  • 10 views
  • 04 Feb, 2022
  • 1 location
Safety and Efficacy of Fecal Microbiota Transplantation

, dysbiotic bowel syndrome, MRSA enteritis, Pseudomembranous enteritis, idiopathic thrombocytopenic purpura (ITP), and atopy. Despite FMT appears to be relatively safe and efficacious in treating a

diarrhea
alcoholic hepatitis
hepatitis
encephalopathy
atopy
  • 427 views
  • 23 Mar, 2022
  • 1 location
Screening and Diagnosing Exercise-induced Bronchoconstriction in Recreational Young Athletes (12-18 y)

The purpose of this study is to validate the screening protocol to study risk factors of exercise-induced bronchoconstriction (EIB) obtained in our previous study in high-school elite athletes (NCT03587675), in recreational young athletes who perform intense physical exercise.

Accepts healthy volunteers
  • 0 views
  • 14 Nov, 2021
  • 1 location
Main Trial of the Cesarean Section and Intestinal Flora of the Newborn Study (MT-SECFLOR)

In this study the investigators assess whether, in CS-delivered infants, the intestinal microbiome could be successfully and safely normalised by postnatal oral transfer of maternal fecal microbiome.

Accepts healthy volunteers
  • 0 views
  • 19 Feb, 2022
  • 1 location
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing (INSTAR)

The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection, stratified by rhinovirus genome load. The secondary objectives are to determine duration and severity of each acute episode with acute expiratory breathing …

steroid therapy
corticosteroid therapy
corticosteroids
wheezing
  • 34 views
  • 29 May, 2022
  • 10 locations
Atopy Network - Comprehensive Allergy Centers: Medical Care of Patients With Moderate to Severe Allergic Diseases (ATAC)

The Atopy Registry aims to assess data about atopic disorders and their medical care in a standardized form. With this, the comparative efficacy, tolerability and safety of systemic therapies

  • 0 views
  • 27 Jul, 2022
  • 1 location