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Found 28 clinical trials
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Efficacy of Systemic Glucocorticoid in the Treatment of Wheezing in Children

are related to the differences in viral etiology, atopy, immunogical maturity or age of the patient. The study aims to answer the following questions: 1. What is the viral etiology of acute

atopy
prednisolone
  • 0 views
  • 07 Nov, 2020
  • 1 location
None
Defining the Severe Paediatric Asthma Endotype

, combining a description of their phenotype (asthma symptoms, atopy, and lung function) associated with histological (airway inflammation and remodelling), immune (innate and adaptive immunity), metabolomics

  • 0 views
  • 29 Nov, 2021
  • 1 location
None
Oral Probiotics to Allergic Pregnant Mother and Their Offspring to Prevent Allergic Disease

The aim of the study is first to detect the difference of the intestinal microbiome between allergic pregnant mother and the non-allergic pregnant mother using the next generation sequence, all postnatal infants will collect the first meconium and feces from one, two, six months to one year old for the …

  • 0 views
  • 22 Jan, 2021
  • 1 location
None
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation

investigation. This work is designed to identify airway factors that are responsible for recruiting cells and associate their airway presence with atopy and asthma.

airway obstruction
allergen
obstruction
atopy
skin prick test
  • 37 views
  • 05 Mar, 2021
  • 1 location
None
Prevention of Dermatitis in Epoxy Exposed Workers

, 4 times during the 2 year follow up period. All participants are patch tested, screened for dermatitis and atopy at start and end of follow up or at end of employment. The investigators also

sensitization
triamcinolone acetonide ointment
  • 9 views
  • 25 Jan, 2021
  • 1 location
None
Safety and Efficacy of Fecal Microbiota Transplantation

, dysbiotic bowel syndrome, MRSA enteritis, Pseudomembranous enteritis, idiopathic thrombocytopenic purpura (ITP), and atopy. Despite FMT appears to be relatively safe and efficacious in treating a

antibiotic
fecal microbiota transplantation
microbiota
antibiotic therapy
diabetes mellitus
  • 313 views
  • 24 Jan, 2021
  • 1 location
None
Screening and Diagnosing Exercise-induced Bronchoconstriction in Recreational Young Athletes (12-18 y)

The purpose of this study is to validate the screening protocol to study risk factors of exercise-induced bronchoconstriction (EIB) obtained in our previous study in high-school elite athletes (NCT03587675), in recreational young athletes who perform intense physical exercise.

Accepts healthy volunteers
  • 0 views
  • 14 Nov, 2021
  • 1 location
None
Main Trial of the Cesarean Section and Intestinal Flora of the Newborn Study

In this study the investigators assess whether, in CS-delivered infants, the intestinal microbiome could be successfully and safely normalised by postnatal oral transfer of maternal fecal microbiome.

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing

The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection. The secondary objectives are to determine duration and severity of each acute episode with acute expiratory breathing difficulty, the number of episodes …

corticosteroids
steroid therapy
wheezing
corticosteroid therapy
  • 34 views
  • 28 Jun, 2021
  • 10 locations
None
Allogeneic Hematopoietic Stem Cell Transplant for People With Primary Immunodeficiency Diseases

Background During a transplant, blood stem cells from one person are given to someone else. The cells grow into the different cells that make up the immune system. This can cure people with certain immunodeficiencies. But transplant has many risks and complications. Objective To see if stem cell transplant can …

mycophenolate mofetil
alemtuzumab
vaccination
allogeneic hematopoietic stem cell transplant
tacrolimus
  • 0 views
  • 12 Sep, 2021
  • 1 location