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Found 101 clinical trials
BioDay Registry: Data Collection Regarding the Use of New Systemic Treatment Options in Patients With Atopic Dermatitis (BioDay)

The BioDay Registry aims to address the need for daily practice data regarding the effectiveness and safety of new systemic treatment options (like biologics and Janus kinase inhibitors) in patients with atopic dermatitis and effect on other atopic comorbidities in a multicenter setting. The registry already consists of several additional …

asthma
dupilumab
food allergy
atopy
  • 69 views
  • 06 Jun, 2022
  • 14 locations
Studies of Skin Microbes in Healthy People and in People With Skin Conditions

This study will examine microbes (e.g., bacteria, fungi, viruses) that live on human skin and how microbes contribute to health and disease. It will analyze healthy human skin and how the these microorganisms might change in patients with atopic dermatitis (AD), a skin condition also known as eczema. Healthy volunteers, …

rash
atopy
Accepts healthy volunteers
examination skin
serum ige
  • 232 views
  • 23 Jul, 2022
  • 1 location
An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis (AD)

The objective of this study is to describe and compare the incidence of adverse pregnancy outcomes (spontaneous abortion/miscarriage, stillbirth) and prevalence of infant outcomes (major congenital malformations [MCMs], small for gestational age [SGA]) in women with AD who are treated with dupilumab during pregnancy relative to women with AD who …

dupilumab
  • 19 views
  • 10 Mar, 2022
Disease Trajectories and Anti-cytokine Response Signatures in Atopic Dermatitis and Psoriasis (DiTrAP)

The clinical study investigates the long-term course of disease in patients with chronic inflammatory skin diseases (atopic eczema and psoriasis) and the impact of tarheted therapies on the clinical and molecular level. For this purpose, patients are asked to take part in regular examinations and data collections, and to donate …

skin disorder
atopy
Accepts healthy volunteers
dermatitis
eczema
  • 31 views
  • 18 Apr, 2022
  • 1 location
Systems Biology of Early Atopy

The goal of this study is to establish a birth cohort that collects prenatal and early life biosamples and environmental samples and rigorously phenotypes young children for food allergy and Atopic Dermatitis (AD) to identify prenatal and early life markers of high risk for food allergy and AD, as well …

food allergy
atopy
  • 0 views
  • 11 Jul, 2021
  • 11 locations
Natural History and Genetics of Food Allergy and Related Conditions

Background About 15 million Americans have a food allergy. Because there are no cures or effective prevention or treatment for food allergies, researchers want to learn more about them. Objective To learn more about the causes and effects of food allergy and related conditions. Eligibility People ages 2 99 who …

prick skin
eosinophilic esophagitis
allergen
Accepts healthy volunteers
food allergy
  • 85 views
  • 27 Jul, 2022
  • 1 location
Prospective Longitudinal Observational Research in Atopic Dermatitis (ProRaD)

Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life. In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within …

allergic rhinitis
atopy
asthma
food allergy
eczema
  • 10 views
  • 16 Mar, 2022
Natural History of Severe Allergic Inflammation and Reactions

Background Allergic inflammation is central to allergy-related diseases and disorders, such as asthma, food allergies, and atopic dermatitis. Atopic dermatitis

urticaria
allergen
atopy
asthma
Accepts healthy volunteers
  • 86 views
  • 25 Jul, 2022
  • 1 location
A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC (TARGET-DERM)

TARGET-DERM is a longitudinal, observational study of adult and pediatric patients being managed for Atopic Dermatitis and other Immune-Mediated Inflammatory Skin Conditions (IMISC) in usual clinical practice. TARGET-DERM will create a research registry of patients with IMISC within academic and community real-world practices in order to assess the safety and …

skin disorder
skin disease
atopy
mediators
dermatitis
  • 4236 views
  • 25 Jul, 2022
  • 47 locations
Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

The Hyper IgE Syndromes (HIES) are primary immunodeficiencies resulting in eczema and recurrent skin and lung infections. Autosomal dominant Hyper IgE syndrome (AD-HIIES; Job's syndrome) is caused by STAT3 mutations, and is a multi-system disorder with skeletal, vascular, and connective tissue manifestations. Understanding how STAT3 mutations cause these diverse clinical …

deficiency
malignancy
Accepts healthy volunteers
immunodeficiency
cancer
  • 105 views
  • 27 Jul, 2022
  • 1 location