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Found 102 clinical trials
Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1% (OP2101-1)

The investigational lotion is envisaged as an short- and long term "Ease & Prevent" monotherapy for adults and children with mild to moderate eczema. With itch representing the most burdensome symptom in eczema, the main objectives with the lotion is fast and efficient itch relief, high tolerability, and high short- …

eczema
fexofenadine
body mass index
Accepts healthy volunteers
topical agents
  • 0 views
  • 29 Jul, 2022
  • 1 location
Effects of Treatments on Atopic Dermatitis

Background Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S. aureus bacteria. Researchers want to study how eczema treatments affect the number and the type of bacteria on the skin. Objectives To study the effect of eczema treatments on skin bacteria. Eligibility Individuals between …

antibiotic therapy
antibiotics
crusting
doxycycline
Accepts healthy volunteers
  • 300 views
  • 11 Aug, 2022
  • 1 location
BROadband vs Narrowband photoTherapy for Eczema Trial Nested in the CACTI Cohort (BRONTE)

Atopic dermatitis (eczema) is a complicated skin condition. In fact, it represents many different underlying problems. These include abnormalities in the skin barrier, the immune system and the

phototherapy
eczema
topical agents
  • 0 views
  • 27 Apr, 2022
  • 1 location
Intervention in Chronic Pediatric Patients and Their Families. (FACTORADAPT)

This project consists of a psychological intervention in patients and their families with different chronic diseases in order to carry out a comparative study between medical pathologies to know which are the protective or risk variables for the adaptation to the disease.

chronic diseases
chronic disease
Accepts healthy volunteers
  • 0 views
  • 05 Apr, 2022
Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases

The molecular mechanisms of action of photo(chemo)therapy in skin diseases are investigated in this study. The phototherapeutic modalities employed include UVB (ultraviolet B), UVA (ultraviolet A), PUVA (psoralen+UVA) and/or extracorporeal photochemotherapy (photopheresis). The study will address whether and how photo(chemo)therapy affects specific biologic pathways in different skin disorders and search …

psoralen
puva
extracorporeal photopheresis
chemotherapy regimen
skin disorder
  • 248 views
  • 21 Jan, 2021
  • 1 location
The Utility of Functionally Relevant Signature Genes in Assessing the Clinical Outcomes of Dupilumab Treatment

The utility of functionally relevant signature genes in assessing the clinical outcomes of dupilumab treatment in the adult onset atopic dermatitis

dupilumab
  • 0 views
  • 10 Mar, 2022
  • 1 location
Safety and Tolerability of BSI-045B in Healthy Adult Subjects and Patients With Atopic Dermatitis

This randomized, double-blind, single center, placebo-controlled, phase 1 single ascending dose (SAD)/multiple ascending dose (MAD) study is designed to assess the safety, tolerability, PK, activity, immunogenicity, and PD of BSI-045B. Approximately 68 subjects will be enrolled. Subjects in this study include 56 healthy volunteers (HVs) and 12 patients with AD. …

Accepts healthy volunteers
eczema
topical agents
  • 0 views
  • 25 Nov, 2021
  • 1 location
China Atopic Dermatitis Registry Study

This regestry study is aimed to characterize the medical care and drug treatment under real-life conditions among Chinese patients with moderate to severe Atopic Dermatitis who are not well controlled by topical therapies.

topical agents
  • 0 views
  • 01 Sep, 2021
  • 1 location
China Type II Inflammatory Skin Disease Clinical Research and Standardized Diagnosis and Treatment Project (CORNERSTONE)

In order to further improve the diagnosis and treatment level of type 2 inflammatory skin diseases, the National Clinical Center for Skin and Immune Diseases established a standardized diagnosis and treatment center for type 2 inflammatory skin diseases to systematically and effectively understand the current treatment status of patients with …

  • 0 views
  • 25 Apr, 2022
  • 1 location
Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis

Atopic dermatitis (AD), also known as eczema, is the most common inflammatory skin disorder of children, affecting 10-20% of children and 1-2% of adults. This skin disorder can be associated with unbearable itchiness and an increased susceptibility to skin infections. The cause of AD is currently poorly understood; therefore, there …

skin infections
Accepts healthy volunteers
food allergy
skin infection
allergic rhinitis
  • 156 views
  • 18 Apr, 2022
  • 4 locations