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Found 145 clinical trials
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Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis

This is a pragmatic, randomized, controlled, equivalency trial. This 12-month trial will evaluate the impact of an online, team-based connected health (TCH) model for management of atopic dermatitis (AD) as compared to in-person care. 300 patients will be randomly assigned to the online TCH model or the in-person control arm. …

atopy
  • 0 views
  • 27 Jan, 2021
  • 1 location
None
The Impact of Dupilumab on Quality of Life in Moderate to Severe Atopic Dermatitis Patients

This is a single-arm, open-label study, which will examine the effect of dupilumab on quality of life in atopic dermatitis patients.

eczema
phototherapy
dupilumab
atopy
  • 84 views
  • 26 Jan, 2021
  • 1 location
None
Immunogenetic Profiling of Dupilumab for the Treatment of Atopic Dermatitis

This is a single-arm, open-label study to examine the effect of dupilumab on the immunologic and genetic environment within atopic dermatitis skin lesions.

eczema
dupilumab
atopy
phototherapy
skin lesion
  • 79 views
  • 21 Aug, 2021
  • 1 location
None
Evaluate Efficacy and Safety of Oral SHR0302 in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis

This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 330 subjects aged 12 to 75 years old with moderate to severe atopic dermatitis.

  • 0 views
  • 15 May, 2021
  • 44 locations
None
Comparative Analysis of Filmed Sequences for the Assessment of Discomfort in Atopic Dermatitis of Infants Under 6 Months of Age

Atopic dermatitis (AD) is an frequent chronic and itchy inflammatory dermatitis which concern about 20% of pediatric population with a revelation usually toward 3-6 months of live. However, there are very few data about the prevalence of pruritus of young infants and about the discomfort linked with it. While the …

childhood atopic dermatitis
atopy
  • 2 views
  • 27 Jan, 2021
  • 1 location
None
Safety and Efficacy in Patients With Moderate to Severe Subacute and Chronic Atopic Dermatitis

A Multicenter, Randomized, Single-Blind, Phase Clinical Trial and Open Label Long-term Observation Study of ADSTEM Inj. to Evaluate the Safety and Efficacy in Patients with Moderate to Severe Subacute and Chronic Atopic Dermatitis. The aim of this study is to evaluate the safety and efficacy of ADSTEM Inj. against Placebo …

topical agents
atopy
  • 50 views
  • 23 Jan, 2021
  • 2 locations
None
A Non-Drug Study Detecting And Quantifying Nocturnal Scratch Behaviors From Wrist Actigraphy Data In Adult Healthy Volunteers And Participants With Atopic Dermatitis (AD)

Sleep disturbance is very common in patients with atopic dermatitis (AD) and is a major factor leading to impaired quality of life. Nocturnal scratching is one of the factors causing sleep disturbance in AD patients. This study aims to develop and validate a digital algorithm for accurately and reliably detecting …

eczema
atopy
scratch
sleep disturbances
Accepts healthy volunteers
  • 202 views
  • 03 Nov, 2021
  • 4 locations
None
The Effectiveness of Antibacterial Therapeutic Clothing Based on Silver or Chitosan as Compared With Non-antibacterial Therapeutic Clothing in Patients With Moderate to Severe Atopic Dermatitis

Since 2000 therapeutic clothing or functional textiles based on silver or chitosan as antibacterial agents were introduced as therapeutics of atopic dermatitis (AD). These agents aim to reduce skin colonization with Staphylococcus (S.) aureus. S. aureus induces further dysregulation of the inflammatory process and increased colonization with S. aureus is …

antihistamines
staphylococcus aureus
atopy
antibiotics
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Safety Tolerability and Efficacy of ZEP-3Na (0.1% or 1%) Compared to Placebo in Subjects With Mild to Moderate Atopic Dermatitis

This is a phase II, double blind study with ZEP-3NA 0.1% or 1% vs. vehicle-control in subjects with mild to moderate Atopic Dermatitis. The IP (Investigational Product) will be administered topically twice daily for 12 weeks. The purpose of this study is to assess the safety, tolerability and efficacy of …

atopy
  • 8 views
  • 25 Mar, 2021
  • 9 locations
None
Brief Cognitive Behavioral Therapy to Treat Itch Rumination "Itch CBT" in Eczema

The main purpose of this study is to adapt cognitive behavior therapy (CBT) to improve itch in children with eczema.

  • 0 views
  • 13 Mar, 2021
  • 1 location