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Found 101 clinical trials
Jaktinib Hydrochloride Cream For Atopic Dermatitis

This study includes a dose escalation part and a dose extension part.

  • 0 views
  • 09 Dec, 2021
  • 1 location
The Role of IL-22/IL-22BP Axis in Atopic Dermatitis (DA/IL-22BP)

Interleukin 22 (IL-22) is known to be regulated by IL-22 binding protein (IL-22BP), a soluble, inhibitory receptor. The potential role of IL-22BP in atopic dermatitis (AD) is mostly unknown and deserves further investigation. The main objective of this study is to better understand the potential protective role of IL-22BP through …

  • 0 views
  • 04 Jul, 2022
  • 1 location
Safety and Efficacy in Patients With Moderate to Severe Subacute and Chronic Atopic Dermatitis

A Multicenter, Randomized, Single-Blind, Phase Ⅱ Clinical Trial and Open Label Long-term Observation Study of ADSTEM Inj. to Evaluate the Safety and Efficacy in Patients with Moderate to Severe Subacute and Chronic Atopic Dermatitis. The aim of this study is to evaluate the safety and efficacy of ADSTEM Inj. against …

atopy
topical agents
  • 325 views
  • 22 Mar, 2022
  • 2 locations
A First-in-Human PoC Study With BEN2293 in Patients With Mild to Moderate Atopic Dermatitis

A randomised, adaptive design, double-blind, placebo-controlled, first-in-human, two-part study to investigate the safety, tolerability, PK and preliminary efficacy of multiple topical doses of BEN2293 in patients with mild to moderate AD.

topical corticosteroid
corticosteroids
topical agents
  • 0 views
  • 26 Apr, 2022
  • 1 location
Apremilast 30 mg BID Combined With Dupilumab

Open label phase 2 investigational study of efficacy and safety of apremilast 30 mg BID in chronic atopic dermatitis when added to the FDA approved treatment dupilumab for atopic dermatitis that is not providing adequate clinical responses.

atopy
dupilumab
vasectomy
treatment regimen
  • 4 views
  • 25 Jul, 2022
  • 1 location
Comparison of Lindioil (Indigo Naturalis Oil Extract) Ointment to Protopic® Ointment 0.1% in Treating Atopic Dermatitis

The aims of this study are: Compare the efficacy of Lindioil ointment and Protopic ointment in treating atopic dermatitis. Compare the safety of Lindioil ointment and Protopic ointment in treating atopic dermatitis. Compare the time to relapse after ceasing of treatment of Lindioil ointment and Protopic ointment. Compare the change …

atopy
tacrolimus
corticosteroids
protopic
  • 34 views
  • 11 Feb, 2022
  • 2 locations
Steroid-reducing Effects of Crisaborole

Atopic dermatitis, or eczema, is a chronic skin condition affecting many children. Crisaborole is a non-steroid topical medication which is FDA approved for children aged 2 and older for eczema. This research study seeks to investigate whether crisaborole reduces topical steroid use in children with atopic dermatitis.

Accepts healthy volunteers
skin disorder
atopy
crisaborole
triamcinolone
  • 68 views
  • 14 Jul, 2022
  • 1 location
An Open Label, Phase 1, Pharmacokinetics, Maximal Usage Pharmacokinetics, Safety, and Efficacy Study of ARQ-151 Cream 0.15% or ARQ-151 Cream 0.05% Administered QD in Adolescent and Pediatric Subjects With Mild to Moderate Atopic Dermatitis

This is a research study where all subjects will receive study medication to understand how the body processes the study medication, and to determine the PK, safety and efficacy of ARQ-151 cream 0.15% or 0.05% in adolescent and pediatric subjects with mild to moderate AD. At entry, subjects in Cohorts …

eczema
  • 42 views
  • 19 Aug, 2022
  • 8 locations
A PHASE 1 FIRST IN HUMAN, RANDOMIZED, DOUBLE BLIND, SPONSOR OPEN, PLACEBO-CONTROLLED, SINGLE- AND MULTIPLE DOSE ESCALATION, PARALLEL GROUP STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF PF 07242813 IN HEALTHY PARTICIPANTS AND PARTICIPANTS WITH ATOPIC DERMATITIS

This is the first time PF-07242813 will be given to humans. The purpose of the study is to evaluate the safety, tolerability, and pharmacokinetics of escalating single and repeat doses of PF-07242813 in healthy participants and in participants with moderate to severe atopic dermatitis. An additional goal is to assess …

Accepts healthy volunteers
asthma
corticosteroids
eczema
topical agents
  • 0 views
  • 16 Sep, 2022
  • 4 locations
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Outpatient Study Evaluating the Pharmacokinetics, Efficacy, and Safety of Baricitinib in Pediatric Patients With Moderate to Severe Atopic Dermatitis (BREEZE-AD-PEDS)

The reason for this study is to see if the study drug called baricitinib works and is safe in children and teenage participants with atopic dermatitis.

corticosteroids
eczema
atopy
baricitinib
ly3009104
  • 142 views
  • 15 Sep, 2022
  • 10 locations