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Found 107 clinical trials
Molecular Signatures in Inflammatory Skin Disease (MSID)

This pilot project intends to examine the utility of a systems medicine approach to identify regulatory networks and their perturbation in psoriasis and atopic dermatitis, and to obtain a comprehensive perspective on disease and disease control by integrating and modelling data across multiple cellular levels and time following specific blockade …

secukinumab
brodalumab
systemic therapy
baricitinib
dupilumab
  • 41 views
  • 26 Apr, 2022
  • 1 location
Study of Skin Microbiome in AD and PS Patients

Everybody's skin has bacteria that normally lives on it. Previous research has shown that people with eczema have higher concentrations of a certain bacteria (S. aureus), especially when their disease is active. The purpose of this study is (a) to see if reductions in another skin bacteria (C. acnes) plays …

dermatitis
Accepts healthy volunteers
staphylococcus aureus
psoriasis
atopy
  • 562 views
  • 02 Jan, 2022
  • 1 location
Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research

This is a tissue, urine, and blood banking protocol for cutaneous t-cell lymphoma (CTCL), eczema, and atopic dermatitis patients for current and future research.

t-cell lymphoma
cutaneous t-cell lymphoma
cutaneous lymphoma
skin biopsy
lymphoma
  • 75 views
  • 22 Jan, 2022
  • 1 location
Metabolic Profiling of Immune Responses in Immune-mediated Diseases

Background The immune system is the part of the body that fights infection. Some people have immune deficiencies that cause skin rashes, make them get sick often with infections, or make it difficult for their skin to heal. Researchers want to learn more to better treat conditions that affect immune …

eczema
psoriasis
Accepts healthy volunteers
  • 0 views
  • 29 Jun, 2022
  • 1 location
The Role of Filaggrin Mutations and Sensitization Pathways in Allergic Rhinitis and Peanut Allergy

Caucasian male and female participants age 18 years of age and older will be enrolled in this study if they have known birch or peanut allergies or known to be non-atopic. Participants will undergo skin testing to confirm their allergies if not completed in the last 12 months. Medications and …

sensitisation
rhinitis
skin test
Accepts healthy volunteers
sensitization
  • 14 views
  • 23 Feb, 2022
  • 1 location
Skin Tracker: A Mobile Health App to Monitor Skin Disease Activity and Treatment Use

Design and beta-test a research-oriented mobile health app to assess disease activity, quality of life, treatment patterns, adverse medication effects, and lifestyle factors in patients with atopic dermatitis.

  • 0 views
  • 13 May, 2022
  • 1 location
Extrinsic and Intrinsic Factors in Atopic Dermatitis Upon Systemic Immune Modulation

Currently, patients with moderate to severe atopic dermatitis are treated with dupilumab if unresponsive to topical treatment. However, not all patients who suffer from atopic dermatitis respond similarly to this treatment. Pattern recognition of immune cells (PRI) is an efficient method to screen patients to allow a more personalized therapy. …

dupilumab
topical agents
eczema
  • 0 views
  • 06 Nov, 2021
  • 1 location