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Found 107 clinical trials
Administration for Placebo Group and Evalution the Safety and Efficacy in Atopic Dermatitis Patients

A Multi-center, Open, Single-arm Clinical Trial to Evaluate the Safety and Efficacy of FURESTEM-AD inj. in Patients with Moderate to Severe Chronic Atopic Dermatitis Who Participated in a Placebo Group in K0102 Clinical Trial: 2nd Extension Study of K0102

  • 0 views
  • 23 Jan, 2021
  • 1 location
Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism

This protocol is primarily looking to see if the IL-4Ra R576 polymorphism is associated with increased clinical, immunological and microbial markers of disease activity in patients with Atopic dermatitis.

  • 0 views
  • 14 May, 2021
  • 1 location
Comprehending Atopic Risk Elements (CARE)

Skin barrier impairment and familial atopy have been implicated as crucial risk factors for the development of atopic dermatitis (AD). Additional risk factors have been explored, including gestational weight, height, age, familial smoking habits, proximity to urban centers and others. However, a comprehensive study focusing on the entire spectrum of …

atopy
Accepts healthy volunteers
  • 0 views
  • 18 Apr, 2022
  • 2 locations
A Pilot Study to Explore the Role of Gut Flora in Eczema

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding eczema.

  • 15 views
  • 28 Feb, 2022
  • 1 location
The Role of Bacterial Toxins in Human Skin Disease

Atopic dermatitis and psoriasis are two skin diseases often associated with bacterial infections and inflammation. Studies indicate that skin cells from these patients may have some changes that make these patients more susceptible to bacterial infections. Inflammatory environment may have an effect on the function of skin cells. The purpose …

elidel
dermatitis
corticosteroids
cyclosporine
bacterial infection
  • 269 views
  • 23 Feb, 2022
  • 1 location
Post-authorization Safety Study in North America to Monitor Pregnancy and Infant Outcomes Following Administration of Dupilumab During Planned or Unexpected Pregnancy

The objective is to evaluate the potential effect of exposure to dupilumab in pregnancy compared to the primary comparison group of disease-matched pregnant women who are not exposed to dupilumab, and the secondary comparison group of healthy pregnant women. The primary outcome of the study is major structural defects, and …

dupilumab
asthma
Accepts healthy volunteers
  • 26 views
  • 18 Feb, 2022
  • 1 location
Skin Barrier Assessment in Pregnancy and at Birth

This is a prospective birth cohort study assessing the role of maternal and environmental factors on the development of allergic diseases in children. Pregnant mothers will be enrolled and we will examine her skin barrier with skin tape strips (STS) and transepidermal water loss (TEWL), along with blood work. We …

food allergy
eczema
wheezing
  • 28 views
  • 25 Jan, 2021
  • 1 location
Skin Barrier Abnormalities and Oxidative Stress Response

This is a prospective, single-site controlled observational study designed to comprehensively determine whether children and adults with atopic dermatitis (AD) and food allergy (FA) have skin abnormalities which distinguish them from children with AD without FA, and non-atopic (NA) controls.

food allergy
asthma
allergic rhinitis
allergen
  • 0 views
  • 25 Jan, 2021
  • 1 location
Observational Study of Conjunctivitis in the Setting of DUPIXENT® Treatment for Atopic Dermatitis

The primary objective of the study is to characterize the clinical phenotype(s) of DUPIXENT®-associated conjunctivitis events. The secondary objectives of the study are to characterize the course of conjunctivitis events during the observation period and collect and assess data on treatment for conjunctivitis events and its effectiveness.

dupilumab
  • 14 views
  • 22 Apr, 2022
  • 11 locations
Study of Skin Microbiome in AD and PS Patients

Everybody's skin has bacteria that normally lives on it. Previous research has shown that people with eczema have higher concentrations of a certain bacteria (S. aureus), especially when their disease is active. The purpose of this study is (a) to see if reductions in another skin bacteria (C. acnes) plays …

staphylococcus aureus
atopy
psoriasis
dermatitis
eczema
  • 510 views
  • 02 Jan, 2022
  • 1 location