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Found 478 clinical trials
Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD)

This study is a prospective, multicenter, parallel, open-label, randomized, controlled, superiority trial. It is planned to recruit 8,250 patients with multi-vessel disease(MVD), and the patients will be followed-up for 12 months after being implanted with a drug-eluting stent (DES) at one of 100 different centers. All patients will be randomly …

aspirin
clopidogrel
antiplatelet therapy
dapt
  • 0 views
  • 25 Jul, 2022
  • 95 locations
iCorMicA - Stratified Medicine in Angina

The iCorMicA study is a multicentre, prospective, randomised, double-blind, sham-controlled, parallel-group, end-point trial and registry. The investigators seek to determine whether stratified medical therapy guided by an adjunctive interventional diagnostic procedure (IDP) during the invasive management of patients with known or suspected angina but no obstructive coronary artery disease improves …

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2) (PICSI-H)

The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over time, and across settings and providers. This study is particularly interested in understanding the effect …

heart failure
dementia
coronary artery disease
alzheimer's disease
liver disease
  • 0 views
  • 21 Mar, 2022
  • 2 locations
Long-term Effectiveness of the Antiobesity Medication Phentermine (LEAP)

The purpose of this research study is to understand the long-term effects of the drug phentermine on weight, blood pressure, other health outcomes, and safety. Phentermine has been approved by the US Food and Drug Administration (FDA) for weight management since 1959, but it has not been approved for long-term …

chronic disease
weight control
fatty liver
type 2 diabetes mellitus
diabetes
  • 0 views
  • 26 Jul, 2022
  • 1 location
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)

Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will …

carotid revascularization
endarterectomy
angiography
stenosis
ischemic attack
  • 1155 views
  • 19 Jun, 2022
  • 134 locations
Evolocumab or Normal Strategies to Reach LDL Objectives in Acute Myocardial Infarction Upbound to PCI

AMUNDSEN-real is a phase IV, international (7 European countries), multicenter, controlled, open label study randomized, in 2 parallel groups of patients with a diagnosis of STEMI or NSTEMI with an indication for PCI, using the PROBE study design (Prospective Randomised Open, Blinded Endpoint). The objective of this study is to …

  • 0 views
  • 10 Oct, 2021
Randomization of Single vs Multiple Arterial Grafts (ROMA)

The primary hypothesis of ROMA is that in patients undergoing primary isolated non-emergent coronary artery bypass surgery (CABG), the use of two or more arterial grafts compared to a single arterial graft is associated with a reduction in the composite outcome of death from any cause, any stroke, post discharge …

bypass surgery
myocardial infarction
revascularisation
infarct
bypass graft
  • 131 views
  • 30 Apr, 2022
  • 56 locations
Non-invasive Photoacoustic Imaging of Skin Inflammatory Disorders With Machine Learning-assisted Scoring

Inflammatory skin disorders are usually assessed by disease scoring system such as Scoring AD (SCORAD)/Eczema Area and Severity Index (EASI) and Psoriasis Area and Severity Index (PASI) for atopic eczema and psoriasis respectively. The current approach to score the severity of these inflammatory skin disorders is through clinical observations and …

plaque psoriasis
Accepts healthy volunteers
dermatitis
diabetes
eczema
  • 4 views
  • 19 Apr, 2022
  • 1 location
Angiographic Control vs. Ischemia-driven Management of Patients Treated With PCI on Left Main With Drug-eluting Stents (PULSE)

The present study aims to compare a planned angiographic control (PAC) follow-up strategy vs. conservative management for patients treated with drug-eluting stents on unprotected left main artery in a prospective, randomized setting. PAC will be performed by coronary computed tomography (CCT), to avoid the limitations of the invasive coronary angiography …

angiography
ischemia
revascularisation
  • 3 views
  • 15 Feb, 2022
  • 1 location
Danish Cardiovascular Screening Trial II (DANCAVAS-II)

This study attempts to reduce social inequality in cardiovascular health by performing an interventional screening trial on how best to decrease cardiovascular disease (CVD) among people with low social status.

cardiovascular disease
  • 13 views
  • 06 Feb, 2022
  • 4 locations