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Found 295 clinical trials
Microbiome and Polycystic Ovaries

Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder among women in reproductive age with an estimated prevalence of 5% to 19.5%. It is a chronic complex syndrome with psychological (depression and anxiety), reproductive and metabolic abnormalities. The etiology seems to be multifactorial. Lately, interest regarding the association between …

endocrine disorder
insulin resistance
  • 26 Apr, 2022
  • 1 location
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN)

Despite advancements in medical care, ischemic heart disease (IHD) remains the leading global cause of death. IHD develops through lipid accumulation into the coronary arteries with subsequent formation of larger atherogenic plaques. During myocardial infarction (MI), a plaque ruptures and subsequent occlusion leads to a death of the heart muscle. …

  • 26 Jan, 2021
  • 1 location
Passive Limb Movement: A Tool to Assess Vascular Health and Guide Rehabilitation

Brief Summary: Current U.S. Veteran demographics reveal an aging population with significant cardiovascular dysfunction. This ultimately manifests as mobility limitation, inactivity, and a subsequent worsening of cardiovascular disease (CVD) that often leads to death. However, despite this clear negative cycle of events, there is not a single clinically accepted, and …

cardiac rehabilitation
cardiovascular disease
Accepts healthy volunteers
endothelial dysfunction
  • 21 Mar, 2022
  • 1 location
The Cardiovascular Effect of GLP-1 Agonist, SGLT2 Inhibitor and Their Combination

Four groups of patients with type 2 diabetes mellitus with high or very high cardiovascular risk will be studied before and after 3 months of treatment: 40 patients treated with a combination of GLP1 analogue and SGLT2 inhibitor ± metformin 40 patients treated with GLP-1 agonist as a second step …

  • 30 Sep, 2023
  • 1 location
Evaluation of Effectiveness and Safety of Rotational Atherectomy in Routine Clinical Practice (IRIS-ROTA)

This study evaluates the effectiveness and safety rotational atherectomy in routine clinical practice.

percutaneous coronary intervention
  • 25 Feb, 2022
  • 1 location