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Found 44 clinical trials
Featured trial
Role of Genetic Factors in the Pathogenesis of Lung Disease

This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes …

pulmonary fibrosis
bronchoscopy
pulmonary disease
diabetes
  • 120 views
  • 23 Nov, 2020
  • 1 location
None
The Effects of the Inspiratory Muscle Plus Aerobic Training Compare to Aerobic Training Alone in Heart Failure Patients.

This study aims to compare effects of inspiratory muscle training added by aerobic training to aerobic training alone in heart failure patients with inspiratory muscle weakness. To do so, strength and endurance of inspiratory muscles, functional capacity, quality of life, heart rate variability and sleep apnea evaluations will be conducted …

  • 5 views
  • 07 Nov, 2020
  • 1 location
None
Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax

The estimated recurrence rate of primary spontaneous pneumothorax is 23-50% after the first episode, and the optimal treatment remains unknown. In the recently published British Thoracic Society (BTS) guidelines, simple aspiration is recommended as first line treatment for all primary pneumothoraces requiring intervention. However, the 1 year recurrence rate of …

pleurodesis
minocycline
aspiration
spontaneous pneumothorax
thoracoscopy
  • 2 views
  • 07 Nov, 2020
None
Home Hospital for Suddenly Ill Adults

The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be delivered in the home with equal quality and safety, reduced cost, and improved patient …

nephropathy
asthma
heart failure
pneumonia
diabetes
  • 23 views
  • 24 Sep, 2021
  • 1 location
None
Enhancing Community Health Through Patient Navigation Advocacy and Social Support

Some patients who have multiple long-term health conditions have significant challenges accessing needed services despite available primary care and social services resources. Patient navigation programs may help those with complex health conditions improve their care and outcomes and if delivered by community health navigators (CHNs) who have close community ties, …

diabetes
nephropathy
asthma
obstructive lung disease
chronic disease
  • 166 views
  • 29 Apr, 2021
  • 1 location
None
Deployment o the Multidisciplinary Prospective Cohort Imminent

Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and emotional repercussions. Beyond this burden, IMIDs share many common pathophysiological mechanisms and treatments, known as "targeted therapies". Despite …

disease or disorder
  • 0 views
  • 24 May, 2021
  • 1 location
None
Effects of Regular Submaximal Exercise on Asthma Control and Quality of Life in Patients With Persistent Symptoms

The effects of regular exercise on asthma control has not yet been well demonstrated. The aim of this study is to investigate the impact of submaximal physical exercise on quality of life, on symptomatic control, and on bronchial and systemic inflammatory markers in patients with persistant asthma.

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Efficacy of Pregabalin on Chronic Cough

The purpose of this study is to determine if Pregabalin, a medication used for the treatment of seizures and chronic pain, can be used to effectively treat people who suffer from non-asthmatic

asthma
chest x-ray
chronic pain
methacholine
  • 138 views
  • 26 Jan, 2021
  • 1 location
None
Safety Tolerability and Pharmacokinetic Study of LTI-03 in Healthy Adult Subjects

, subjects must have normal pulmonary function at Screening and will be excluded if they have a history of active or recurring allergies, asthma, chronic obstructive pulmonary disease (COPD), chronic sinus

pulmonary disease
body mass index
COPD
  • 244 views
  • 19 Sep, 2021
  • 1 location
None
Individualized Diagnosis and Treatment of Extraesophageal Reflux in Patients With Chronic Cough

Chronic cough is a very unpleasant symptom, significantly reduces the patient's quality of life, and bothers the neighborhood. A very common cause or co-factor of chronic cough is extraesophageal reflux (EER). The aim of the project is the precise diagnosis of EER in patients with chronic cough (in patients with …

  • 0 views
  • 06 Aug, 2021
  • 1 location