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Found 28 clinical trials
Proportional Ventilation and Ventilatory Synchronism

Synchronism of gas flow delivered by the ventilator and muscular effort of the patient will be studied during two kinds of ventilation. The first one is the proportional assisted

  • 07 Nov, 2020
  • 1 location
Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis

avoided. Theoretically the use of a volume assisted ventilation may overpass this problem of frequent variations of the settings, since the provision of a fixed tidal volume may always

non-invasive ventilation
lung disease
respiratory failure
maximal inspiratory pressure
assisted ventilation
  • 07 Nov, 2020
  • 1 location
Cardiovascular Consequences of NIV Withdrawal in Patients With Myotonic Dystrophy

Background: Myotonic dystrophy lead to highly heterogeneous, multisystemic symptoms including myotonia, progressive muscle weakness, cardiac conduction defects, cataract, metabolic dysfunction, and excessive daytime somnolence. This last symptom is related to respiratory failure and/or to involvement of the central nervous system. However the metabolic disturbances could contribute to it. From the …

  • 07 Nov, 2020
  • 1 location
Use of Inhaled High-molecular Weight Hyaluronan in Patients With Severe COVID19: Feasibility and Outcomes

To determine whether inhaled Yabro protects against progression of COVID19-induced respiratory failure preventing the passage to non-invasive ventilation (NIV) and promotes recovery from COVID19 lung disease in hospitalized patients.

  • 07 Apr, 2021
  • 1 location
Patient-centered Mobile Technology Interventions to Improve Maternal Health in Uganda

Ugandan women and their children suffer from high maternal mortality (360 for every 100,000 women) and perinatal mortality (41 deaths per 1000 births). Only 58% of pregnant women attend at least 4 Antenatal Care (ANC) visits (of the recommended 8) and only 70% deliver with a skilled attendant. The design …

  • 27 Jan, 2021
  • 1 location
VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infants

The purpose of this study is to determine whether providing ventilatory assistance prior to umbilical cord clamping influences the occurrence of intraventricular hemorrhage (IVH) in extremely preterm (EPT) infants, compared to standard care of providing ventilatory assistance after cord clamping.

umbilical cord clamping
  • 19 Feb, 2021
  • 13 locations
Non-invasive Ventilation Following Extubation (Prophylactic) to Prevent Extubation Failure in Critically Obese Patients

Mechanical ventilation is the first artificial support used in intensive care. After a period of invasive mechanical ventilation, patients should be separated from the ventilator (weaning period of mechanical ventilation). If weaning and extubation (removal of the tracheal tube) are successful in approximately 80 to 90% of resuscitation patients, 10 …

  • 23 Jan, 2021
  • 1 location
Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study

For adult patients with acute respiratory failure requiring invasive mechanical ventilation, does a ventilation strategy using proportional assist ventilation with load-adjustable gain factors (PAV+) result in a shorter duration of time spent on mechanical ventilation than a ventilation strategy using pressure support ventilation (PSV)?

mechanical ventilation
pressure support
  • 24 Jan, 2021
  • 24 locations
Prevention of Epilepsy by Reducing Neonatal Encephalopathy

The aim of the study is to examine if a pragmatic, evidenced based and generalisable intrapartum care bundle involving birth companions and empowering mothers will reduce birth injury-related epilepsy at 18 months of age in India. The care bundle will have four key elements (interventions): (1) birth companion providing constant …

  • 25 Jan, 2021
  • 3 locations
Bag-Valve-Guedel Adaptor vs Common Face Mask for the Ventilation of Anesthetized Bearded Men

Ventilation of a bearded patient with the commonly used face mask has low efficiency because of difficulties to achieve a tight seal around the mouth and nose. The purpose of this study is to evaluate the efficacy of a novel bag valve Guedel adaptor (BVGA) that enables the direct connection …

  • 28 Jan, 2021
  • 1 location