Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 113 clinical trials
Comparative Study of Rifaximin Versus Norfloxacin in the Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

The aim of the study is to compare the effectiveness of rifaximin versus norfloxacin for secondary prevention of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

spontaneous bacterial peritonitis
ascites
secondary prevention
peritonitis
rifaximin
  • 9 views
  • 22 Jan, 2021
  • 1 location
Evaluation of Postoperative Ascites After Somatostatin Infusion Following Hepatectomy for Hepatocellular Carcinoma (SOMAPROTECT01)

Most patients undergoing hepatectomy for hepatocellular carcinoma (HCC) suffer from underlying liver disease and are exposed to the risk of postoperative ascites, with subsequent morbidity

cancer
liver cancer
liver disease
cirrhosis
hepatectomy
  • 12 views
  • 22 Mar, 2022
  • 7 locations
A Multi-Center, Randomized, Placebo-Controlled, Double-Blind, Adaptive Dose-Ranging Study to Assess Safety and Efficacy of Intravenous OCE-205 in Adults Diagnosed With Cirrhosis With Ascites Who Have Developed Hepatorenal Syndrome-Acute Kidney Injury (HRS-AKI)

OCE-205 is being tested to treat participants who have developed Hepatorenal Syndrome-Acute Kidney Injury as a complication of cirrhosis with ascites. The study aims are to evaluate the

hepatorenal syndrome
ascites
  • 0 views
  • 24 Oct, 2022
  • 12 locations
Efficacy and Safety of Midodrine in Refractory or Recurrent Ascites in Children With Cirrhosis.

Refractory ascites is seen in 17% of cirrhotic patients with the 1year mortality rate being high, upto 20-50% [1]. The pathogenesis of cirrhotic ascites includes release of vasodilatory

  • 0 views
  • 20 Nov, 2021
  • 1 location
Efficacy and Safety of Carvedilol in Cirrhosis Patients With Uncomplicated Ascites Without High Risk Esophageal Varices

The cumulative risk of refractory ascites is in the order of 20% within five years of the development of ascites. An elevated sinusoidal pressure is essential for the development of ascites, as

spontaneous bacterial peritonitis
vasopressin
esophageal varices
carvedilol
paracentesis
  • 0 views
  • 06 Nov, 2021
  • 1 location
GAIA-102 Intraperitoneal Administration in Patients With Advanced Gastrointestinal Cancer of Microsatellite Stable With Malignant Ascites

malignant ascites, and determine the recommended number of doses for Phase II part. Phase II Part : Research the efficacy and safety of as a single agent or GAIA-102 and pembrolizumab for

drainage
gastrointestinal cancer
adenocarcinoma
pembrolizumab
gastric adenocarcinoma
  • 0 views
  • 11 Jul, 2022
  • 1 location
A Phase Ia/Ib, Open-label, Single-arm, Dose-escalation and Expansion Study of Specific Dual-targeting VEGFR1 and PD-L1 CAR-T in Cancer Patients With Pleural or Peritoneal Metastases

Serosal cavity metastases of malignant tumor seriously affects the quality of life and survival time of patients with cancers in advanced stage. VEGFR1 is frequently expressed in breast cancer, ovarian cancer, lung cancer, gastric cancer and other malignant tumors and their metastases. The VEGFR1/PD-L1 dual-targeting CAR-T will be investigated in …

  • 0 views
  • 14 Oct, 2022
  • 1 location
An Open Label, Randomized Controlled Clinical Study on the Safety and Efficacy of Virus Activated Killer Immune Cells (VAK) in the Treatment of Malignant Pleural and Peritoneal Effusion

Theory of VAK: Immune cells (T cells for example) of cancer subjects may be domesticated by the tumor microenvironment, and have low efficacy to kill cancer cells. They could be restimulated by virus antigen, and play a powerful tumor killing role while intrapleural to subjects. Releasing of tumor-associated antigen could …

cancer
malignant pleural effusion
anti-coagulant
tumor cells
  • 0 views
  • 25 Oct, 2022
  • 1 location
Single Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics

This single ascending dose (SAD) study evaluates PHIN-214, being studied to determine the safety, tolerability, and pharmacokinetics, and establish the maximum tolerated dose of this compound in patients with compensated cirrhosis.

body mass index
fibroscan
terlipressin
  • 0 views
  • 07 Oct, 2022
  • 2 locations
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis (RED-C-3131)

overt hepatic encephalopathy (OHE) decompensation in advanced liver cirrhosis, defined by the presence of medically controlled ascites.

cirrhosis
liver disease
screening procedures
rifaximin
mini-mental status exam
  • 1 views
  • 10 Oct, 2022