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Found 11 clinical trials
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Efficacy and Safety of Cetuximab in Combination With Cisplatin Gemcitabine as First-Line Therapy in Advanced NSCLC

Lung cancer is the leading cause of cancer deaths worldwide. It is estimated that, in 2004, 173,700 new cases of lung cancer will be diagnosed in the United States alone and 164,440 deaths due to this disease will occur(13) . NSCLC accounts for approximately 80% of all lung cancers. Among …

stage iv non-small cell lung cancer
cetuximab
neutrophil count
platinum-based chemotherapy
secondary malignant neoplasm of liver
  • 3 views
  • 07 Nov, 2020
  • 1 location
None
Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen

TREOCAPA is a Phase II/III European Multicentre study concerning the prophylactic treatment by Acetaminophen of extremely preterm infant during the first five days after birth. The Phase II is a dose finding phase in order to assess the minimum effective dose regimen of acetaminophen for the closure of PDA for …

  • 0 views
  • 01 Jul, 2021
  • 23 locations
None
Stereotactic Body Radiation Therapy (SBRT) Efficiency and Toxicity in Liver Cancer

Intervention research involving the human person, phase II, prospective, multicentric, non-randomized and multi-cohort study. The eligibility criteria are broad, on purpose, so every patient, able to be treated by SBRT and unable to participate in another trial (non eligible patient or non included centers), can be included in this national …

  • 0 views
  • 01 Nov, 2021
  • 10 locations
None
Safety and Immunogenicity of Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545])

This study will be the first time that the candidate malaria vaccine Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545]) will be tested in malaria endemic populations. The phase Ib study will include adults who will be randomly allocated to either receive the malaria vaccine or the vaccine against Tetanus. Each participant will …

vaccination
tetanus
  • 3 views
  • 07 Nov, 2020
  • 1 location
None
Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Randomized Against Valaciclovir - STEP 1 (CYMEVAL3-STEP1)

In the model of the perfused cotyledon, Letermovir crosses the placenta to reach appropriate fetal concentration. The cotyledon model can only be performed in the third trimester placenta. Although it is probable that the transplacental passage in the second trimester is in the same range than the one found in …

Accepts healthy volunteers
  • 0 views
  • 27 Nov, 2021
  • 1 location
None
Treatment of Graves Ophthalmopathy With Simvastatin (GO-DS)

In an investigator initiated multicenter trial (Malm, Odense, rhus) the investigators aim at evaluating activity of Gravesophthalmopathy (GO) and progress to severe GO in patients with mild to moderate Graves ophthalmopathy treated with simvastatin or no treatment.

graves' disease
hyperthyroidism
thyroidectomy
exophthalmos
thyroxine
  • 53 views
  • 25 Nov, 2021
  • 4 locations
None
Health and Exercise Response in Children With Chronic and Auto-immune Pathologies

The aim of the present project is to assess the effects of the chronic diseases and their associated treatments chronic paediatric diseases (CPD), to further understand their impact on physical fitness for public health perspectives. This is an innovative approach in the treatment of chronic paediatric diseases . This project …

chronic disease
fatigue
chronic inflammation
  • 6 views
  • 22 Jan, 2021
  • 1 location
None
Thromboembolic Risk Screening in Patients With Cancer and COVID-19

Study Rational Since December 2019, outbreak of COVID-19 caused by a novel virus SARS-Cov-2 has spread rapidly around the world and became a pandemic issue. First data report high mortality in severe patients with 30% death rate at 28 days. Exact proportions of the reasons of death are unclear: severe …

cardiomyopathy
pulmonary embolism
cancer
primary cancer
venous thromboembolism
  • 0 views
  • 15 Dec, 2021
  • 7 locations
None
South Danish Obesity Initiative, Screening for Unrecognized Obesity Related Disease

People with BMI >30 kg/m2 will be included in at population-based cohort. Additionally, one control group with BMI 18.5-25 kg/m2 and one control group with BMI 25-30 kg/m2 will be included. All participants with age 18 and 60 years. To evaluate health status participants will be screened by for undetected …

a 12
Accepts healthy volunteers
hypertension
diabetes
dyslipidemia
  • 0 views
  • 10 Jan, 2022
None
The Relationship Between Serum rT3 Concentrations T3/T4 Ratio and Symptoms/Quality of Life in Treated Hypothyroid Patients

The aim of this study is to evaluate the relationship between serum rT3 (serum reverse triiodothyronine) concentrations, T3/T4 (triiodothyronine/thyroxine) ratio, and persistent symptoms /quality of life in treated hypothyroid patients. Investigators are going to measure TSH (thyroid stimulating hormone), free-T3, free-T4, reverse-T3 levels, biochemical markers of hypothyroidism and quality of …

  • 0 views
  • 04 Oct, 2021
  • 1 location