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Found 678 clinical trials
Featured trial
A trial evaluating TEPEZZA® in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

The overall objective is to investigate the safety, tolerability and effect on insulin-like growth factor-1 (IGF-1), inflammatory and fibrotic biomarkers of TEPEZZA® administered once every 3 weeks (q3W) for 24 weeks in the treatment of participants with diffuse cutaneous systemic sclerosis (dcSSc).

  • 6 views
  • 11 Aug, 2022
  • 5 locations
Featured trial
Study to evaluate HZN-825 in patients with Diffuse Cutaneous Systemic Sclerosis (dcSSc)

The goal is to determine the efficacy, safety and tolerability for 300 patients with Diffuse Cutaneous Systemic Sclerosis (dcSSc) assigned to either one of 2 dose regimens of HZN-825 (administered once daily (QD) or twice daily (BID)), or a placebo regimen for 52 weeks.Participants who complete all study visits may …

rheumatism
MRSS
diffuse cutaneous systemic sclerosis
raynaud's syndrome
raynaud's phenomenon
  • 16 views
  • 19 Dec, 2022
  • 85 locations
Featured trial
Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)  

Primary Objective: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on pulmonary function in former …

  • 778 views
  • 08 Feb, 2023
  • 90 locations
Featured trial
Rheumatoid Arthritis Research Study

Rheumatoid Arthritis research study enrolling in the Tampa Bay Area.  

  • 198 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Rheumatoid Arthritis Research Study

We are looking for patients 18-75 years of age who have been diagnosed with moderate to severe rheumatoid arthritis.  

  • 202 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Randomized, Double-blind, Placebo-controlled, Multicenter Phase 2b/3 Study to Evaluate the Efficacy and Safety of Izokibep in Subjects with Active Psoriatic Arthritis

Psoriatic Arthritis Study to evaluate the efficacy and safety of izokibep in subjects who are TNFi naïve or who have been previously treated with 1 or more TNFi. 

  • 0 views
  • 30 Dec, 2022
  • 1 location
Featured trial
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Giant Cell Arteritis

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Giant Cell Arteritis  

  • 82 views
  • 23 Nov, 2020
  • 1 location
Featured trial
The effect of daily intake of two different doses of Bifidobacterium Breve Bif195 on small-intestinal damage induced by Acetlysalicylic Acid- a randomized, double-blind, placebo-controlled, three-armed, parallel group trial in healthy volunteers.

arthritis. Long-term use of low-dose NSAIDS are also recommended and prescribed for their heart-protecting properties.  However, low dose use of NSAIDS, such as Aspirin, is associated with damage

  • 848 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Rheumatoid Arthritis

Rheumatoid Arthritis

  • 435 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Moderate to Severe Rheumatoid Arthritis (RA)

Adults with rheumatoid arthritis have an increased risk of blood clots. This research study is comparing the risk of blood clots among patients treated with certain study medications. &nbsp

  • 64 views
  • 23 Nov, 2020
  • 1 location