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Found 26 clinical trials
High Dose Steroids in Children With Stroke (PASTA)

This clinical trial deals with focal cerebral arteriopathy and childhood stroke, a rare but devastating condition. Focal cerebral arteriopathy (FCA) is an inflammatory vessel wall disease

  • 12 Mar, 2022
  • 3 locations
Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome (TARDIS)

This study will be the first to evaluate the role played by potential precipitating factors and risk factors in Reversible Cerebral Vasoconstriction Syndrome (RCVS) through of prospective selection of carefully characterised patients and controls. The impact of these factors on the prognosis will be evaluated through a follow-up assessment of …

Accepts healthy volunteers
  • 20 Feb, 2022
  • 1 location
Arteriovenous Fistulae: Drug-eluting Balloon Angioplasty (FAVABED)

Dysfunctions such as tight stenosis or thrombosis in haemodialysis vascular accesses are the leading cause of hospitalisationand morbidity in chronic haemodialysis patients incurring significant related costs estimated at over one billion dollars in the USA. Dysfunctions of these vascular accesses are generally treated by conventional angioplasty as this is the …

  • 24 Feb, 2022
  • 8 locations
ACT Guided Heparinization During Open Abdominal Aortic Aneurysm Repair. (ACTION-1)

Aim of the ACTION-1 study is to determine whether ACT guided heparinization decreases thrombo-embolic complications (TEC) and mortality after elective open AAA surgery, without causing more bleeding complications.

open repair
aaa surgery
aneurysm repair
aortic aneurysm
  • 02 Mar, 2022
  • 18 locations
European/International FMD Registry and Initiative (FEIRI)

(patients with multiple dissections and/or aneurysms without string-of-beads, focal stenosis or evidence of inherited arteriopathy) (iv) To contribute to the unravelling of genetic, proteomic and

  • 16 May, 2022
  • 1 location
Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Ulinastatin) II

Acute Aortic Syndrome (AAS) is a common feature of acute aortic wall events, including aortic dissection, intramural hematoma, aortic ulceration and aortic trauma, and occurs in up to 35 cases per 100,000 cases per year between the ages of 65 and 75 years. Ulinastatin has antiinflammatory activity and suppresses the …

artery diseases
  • 22 Aug, 2021
  • 2 locations
Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Rosuvastatin) I

Acute Aortic Syndrome (AAS)/Aortic Aneurysm is a common feature of aortic wall events, including aortic dissection, intramural hematoma, aortic ulceration and aortic trauma, and occurs in up to 35 cases per 100,000 cases per year between the ages of 65 and 75 years. Increased levels of the inflammatory biomarker high-sensitivity …

  • 05 Aug, 2021
  • 2 locations
Effect of a Neuromuscular Electrical Stimulation Program on Walking Capacity in Peripheral Artery Disease Patients (ELECTROPAD)

Lower extremity peripheral arterial disease (LEPAD) is a highly prevalent chronic disease. Cardiovascular mortality of LEPAD patients at five years ranges between 18 to 30%. LEPAD is primarily caused by atherosclerosis that induces an inadequate blood flow to meet the tissues demand due to the narrowing of the arteries. An …

Accepts healthy volunteers
  • 16 May, 2022
  • 5 locations
Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function (TREAT-SVDs)

sporadic small vessel diseases (SVDs) and in 30 patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)

  • 11 Mar, 2022
  • 5 locations
Laser-excimer Versus High-pressure Dilation to Treat Under-expansion of the Stent (LASER EXPAND)

The laser-excimer technology could be an essential tool to correct the under-expansion of the stent once it has been implanted unless severe calcification. The laser-excimer technology achieves a greater minimum luminal area when treating an infra-expanded stent, when compared with the results obtained with the simple dilatation at high or …

  • 19 Apr, 2022
  • 6 locations