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Found 1046 clinical trials
Evaluation of Cerebrovascular Events in Patients With Occlusive Carotid Artery Disorders

As of today, no suitable multiparametric predictive method is available to properly estimate stroke risk in patients with carotid artery stenosis. Carotid artery stenosis is one of the proven risk factors of stroke incidence, but the indication of its intervention is merely the grade of stenosis itself. The current international …

ischemia
stroke
stenosis
angiography
endarterectomy
  • 0 views
  • 02 Mar, 2022
  • 1 location
Use of Sublingual Microcirculation and FloTrac Monitoring During Major Vascular Surgery and Its Effect on Hospital LOS

the aim of this study is to determine whether an intraoperative optimization protocol using the enhanced flow-based hemodynamic parameters of the FloTrac/Vigileo device in combination with intraoperative measurement of the sublingual microcirculation with the Cytocam-IDF device would result in an improvement in outcome in high-risk patients undergoing major vascular surgery, …

stroke
aortic aneurysm
aneurysm
aneurysm repair
vascular surgery
  • 0 views
  • 18 Nov, 2021
  • 1 location
A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation (CHAMP)

Patients undergoing semi-elective lower extremity major amputation from complications associated with atherosclerotic limb ischemia will received intra-muscular injections of allogeneic Mesenchymal Stromal Cells in the leg above and below the point of amputation to prevent ischemic wound complications after surgery and decrease the incidence of revision and further amputation.

ischemic wound
ischemia
gangrene
limb ischemia
  • 49 views
  • 25 Feb, 2022
  • 1 location
The Value of Screening for HPR in Patients Undergoing Lower Extremity Arterial Endovascular Interventions

This is a randomized controlled trial designed to evaluate the role of screening for and intervening on patients with high on treatment platelet reactivity undergoing lower extremity arterial endovascular interventions.

arterial disease
peripheral vascular disease
clopidogrel
endovascular intervention
vascular disease
  • 1 views
  • 14 Jun, 2022
  • 1 location
Primary FIbrinolysis and Secondary STenting Versus immEdiate Stenting in ST-segment Elevation Myocardial Infarction (FISSTEMI)

This prospective, multicenter, randomized, controlled, open-label clinical study has a target enrollment of 240 subjects. It will explore whether STEMI patients transferred to a PCI center following thrombolytic therapy and expected to have stent implantation might benefit from an alternative treatment strategy and the use of new technologies designed to …

infarct
thrombolytic therapy
infarction
stemi
myocardial infarction
  • 0 views
  • 20 Apr, 2022
  • 1 location
Optimal Predilatation Treatment Before Implantation of a Magmaris Bioresorbable Scaffold in Coronary Artery Stenosis

The aim of the study is to investigate if lesion preparation with a ScoreFlex balloon compared to a standard non-compliant balloon improve vascular healing and minimize lumen reduction after implantation of a Magmaris bioresorbable scaffold.

infarct
percutaneous coronary intervention
coronary artery stenosis
angina pectoris
stenosis
  • 0 views
  • 12 Dec, 2021
  • 1 location
Phase II Study to Evaluate the Clinical Potential of 68GaNOTA-Anti-MMR-VHH2 for in Vivo Imaging of MMR-expressing Macrophages by Means of Positron Emission Tomography (PET) in Oncological Lesions,Cardiovascular Atherosclerosis,Syndrome With Abnormal Immune Activation and Cardiac sarcoïdosis (MITRAS)

Phase II study to evaluate the clinical potential of 68GaNOTA-anti-MMR-VHH2 for in vivo imaging of Macrophage Mannose Receptor (MMR)-expressing Macrophages by means of Positron Emission Tomography (PET) in patients with oncological lesions in need of non-surgical therapy, patients with cardiovascular atherosclerosis, syndrome with abnormal immune activation and cardiac sarcoïdosis.

atherosclerosis
primary cancer
pet-ct scan
bone marrow procedure
endarterectomy
  • 0 views
  • 23 Sep, 2022
  • 1 location
Prevention of Chest Pain in Chemo-treated Cancer Patients (CATCH)

This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment prior to the 5-FU treatment. The investigators hypothesize that aggressive management of ischemic risk factors in asymptomatic patients will …

calcium
cancer
acute coronary syndrome
fluorouracil
chest pain
  • 12 views
  • 11 Mar, 2022
  • 1 location
Standardized Vascular Rehabilitation Program to Improve Patient Disease and Quality of Life

The purpose of this study is to identify the type of patients being referred for the Vascular Rehabilitation Program (VRP) and to study the success rates of the program according to improvements in walking distance and quality of life surveys. Subjects will be in the VRP for 6-12 weeks and …

rehabilitation program
cardiac rehabilitation
rehabilitation therapy
intermittent claudication
peripheral artery disease
  • 27 views
  • 03 Mar, 2022
  • 1 location
The Effects of Oral Inorganic Nitrate Supplementation on Lower Limb Perfusion During Exercise in Patients With PAD

Peripheral arterial disease (PAD) is a highly prevalent and costly condition. Intermittent claudication (IC), defined as ischemic leg pain that occurs with walking, results in functional impairment, reduced daily physical activity, and a lower quality of life. Although the mechanisms contributing to functional impairment are not fully delineated, current evidence …

arterial disease
ischemia
critical limb ischemia
pain-free
limb ischemia
  • 0 views
  • 26 Sep, 2021
  • 1 location