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Found 1117 clinical trials
Lifestyle Modification Programme for Patients With Peripheral Arterial Disease

This trial randomises patients with occlusive peripheral arterial disease, to be managed either by providing a 12-week structured lifestyle modification programme, or standard healthcare.

total cholesterol
hba1c
exposure to tobacco
angiography
arteriopathy
  • 29 views
  • 05 Feb, 2022
  • 1 location
External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis

Intracranial stenosis is prevalent among Asians and constitute a common cause of cerebral ischemia. While the best medical therapy carries stroke recurrence rates in access of 10% per year, intracranial stenting was associated with unacceptable peri-procedural ischemic events. Cerebral ischemic events are strongly related to the severity of intracranial stenosis, …

stenosis
ischemia
cerebral infarction
acute stroke
stroke
  • 23 views
  • 03 Feb, 2022
  • 1 location
Effect of Intraoperative Iloprost Inhalant on Hemodynamic Stability in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery

Considering that the cause of hemodynamic instability during OPCAB is closely related to right ventricular dysfunction with pulmonary artery hypertension, the use of inhaled iloprost (a selective pulmonary vasodilator) in patients undergoing OPCAB maybe beneficial for hemodynamic management. Previous research has showed that inhaled iloprost reduce pulmonary arterial pressure and …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Clinical Study of Stent Versus Direct Atherectomy to Treat Iliac Artery Occlusive Diseases

This is a randomized study comparing stent and plaque excision systems in treatment of Iliac artery occlusive disease.

  • 0 views
  • 05 Mar, 2022
  • 1 location
European/International FMD Registry and Initiative (FEIRI)

The main objectives of FEIRI are: (i) To describe the demographic and arterial characteristics of FMD and related diseases at a global scale and according to countries and/or ethnic origin (ii) To evaluate the incidence and predictors of novel FMD lesions and complications (iii) To explore the commonalities and differences …

  • 0 views
  • 16 May, 2022
  • 1 location
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy (SONOBIRDIE)

SONOBIRDIE Trial is a randomized, single-blind, sham-controlled study designed for a demonstration of the safety and effectiveness of sonolysis (continual transcranial Doppler (TCD) monitoring) in reduction of risk of stroke or transient ischemic attack (TIA), brain infarctions and cognitive decline using a 2-MHz diagnostic probe with a maximal diagnostic energy …

stenosis
carotid artery stenosis
endarterectomy
angiography
MRI
  • 6 views
  • 02 May, 2022
  • 1 location
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)

Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will …

stenosis
transient ischemic attack
endarterectomy
ischemic attack
angiography
  • 1155 views
  • 19 Jun, 2022
  • 131 locations
Multivessel TALENT

Multivessel TALENT is a prospective, randomized, multi-center study comparing clinical outcomes between SUPRAFLEX Cruz and SYNERGY in approximately 1550 patients with de-novo three vessel disease undergoing percutaneous coronary intervention (PCI). Patients will be treated according to "state of art PCI"; not only treatment strategies based on the latest ESC guideline, …

cholesterol measurement
prasugrel
hmg-coa reductase inhibitor
stenosis
coronary bypass
  • 0 views
  • 09 May, 2022
  • 1 location
Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD)

This study is a prospective, multicenter, parallel, open-label, randomized, controlled, superiority trial. It is planned to recruit 8,250 patients with multi-vessel disease(MVD), and the patients will be followed-up for 12 months after being implanted with a drug-eluting stent (DES) at one of 100 different centers. All patients will be randomly …

dapt
clopidogrel
aspirin
antiplatelet therapy
  • 0 views
  • 02 May, 2022
  • 88 locations
New Heart Imaging Techniques to Evaluate Possible Heart Disease

Background Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other conditions that lead to heart attacks. …

fats
diabetes mellitus
hypertension
blood test
ct scan
  • 336 views
  • 02 Jul, 2022
  • 1 location