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Found 462 clinical trials
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Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion

Coronary angiography is performed to evaluate for obstructive coronary artery disease. This is commonly performed via the transfemoral or transradial approach with the latter increasing in frequency. One of the most common complications of transradial access is radial artery occlusion occurring in ~5% of patients which prohibits the use of …

  • 11 views
  • 26 Jan, 2021
  • 1 location
None
Standard vs High Dose of Unfractionated Heparin in the Incidence of Radial Artery Occlusion (DEFINITION) Trial.

Double blind single center clinical trial to compare the incidence of radial artery occlusion (RAO) using standard doses of Unfractionated Heparin (UFH) vs. high doses of UFH.

  • 0 views
  • 25 Jan, 2021
  • 1 location
None
TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS)

TENecteplase in Central Retinal Artery Occlusion (TenCRAOS): A Prospective, randomized-controlled, double-dummy, double-blind phase 3 multi-centre trial of TNK 0.25 mg/kg + placebo vs. ASA + placebo (2 arms with 1:1 block randomization). A Prospective, randomized-controlled, double-dummy, double-blind phase 3 multi-centre trial of TNK 0.25 mg/kg + placebo vs. ASA + …

  • 0 views
  • 15 Mar, 2021
  • 25 locations
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Head-of-Bed Positioning in Large Artery Acute Ischemic Stroke

outcome. Positioning with the head of bed (HOB) at 0-degree has been shown in small studies to increase cerebral blood flow across arterial occlusion in hyperacute large artery IS, leading to clinical

  • 0 views
  • 17 Oct, 2021
  • 2 locations
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Endovascular Stroke Treatment Only (ESTO) Trial

The specific aims of this study are to: Determine whether the endovascular treatment (mechanical thrombectomy) alone without using intravenous (IV) recombinant tissue plasminogen activator (rt-PA) in acute ischemic stroke patients demonstrates "promise" or a lack thereof ("futility") in deciding what would be the next phase III trial. Determine the proportion …

  • 0 views
  • 05 Mar, 2021
  • 1 location
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Effect of DIRECT Transfer to ANGIOsuite on Functional Outcome in Severe Acute Stroke

Rationale: Acute large-vessel strokes, requiring endovascular treatment, are currently being managed through radiology department before being transferred to the angiography room. However, patients with severe neurological deficit have demonstrated even greater benefits from recanalization as the symptom onset-to-reperfusion time is shortened to less than 1 hour. Recent pilot study have …

  • 0 views
  • 25 Jan, 2021
  • 1 location
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Clinical Study of Stent Versus Direct Atherectomy to Treat Iliac Artery Occlusive Diseases

This is a randomized study comparing stent and plaque excision systems in treatment of Iliac artery occlusive disease.

  • 0 views
  • 24 Jan, 2021
  • 1 location
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Lifestyle Modification Programme for Patients With Peripheral Arterial Disease

This trial randomises patients with occlusive peripheral arterial disease, to be managed either by providing a 12-week structured lifestyle modification programme, or standard healthcare.

peripheral vascular disease
hba1c
total cholesterol
angiography
tobacco in any form
  • 26 views
  • 14 Aug, 2021
  • 1 location
None
Effect of Intraoperative Iloprost Inhalant on Hemodynamic Stability in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery

Considering that the cause of hemodynamic instability during OPCAB is closely related to right ventricular dysfunction with pulmonary artery hypertension, the use of inhaled iloprost (a selective pulmonary vasodilator) in patients undergoing OPCAB maybe beneficial for hemodynamic management. Previous research has showed that inhaled iloprost reduce pulmonary arterial pressure and …

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
A Phase III Randomized Blind Double Dummy Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion

The aim of the THEIA study is to determine if Alteplase administrated within 4.5 hours improve visual deficit due to acute CRAO with a good safety profile.

  • 22 views
  • 11 Nov, 2021
  • 28 locations