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Found 9 clinical trials
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Pilot Randomized Trial With Flecainide in ARVC Patients

Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inherited arrhythmia disorder with high risk of ventricular tachycardia or fibrillation, and implantable cardioverter defibrillator remains as therapy of choice. Antiarrhythmic therapy with different agents including beta-blockers, sotalol and amiodarone are usually not effective in reducing risk of arrhythmic events. Recent data indicated …

beta blockers
antiarrhythmic drug
fibrillation
amiodarone
bisoprolol
  • 41 views
  • 17 Sep, 2021
  • 6 locations
None
DNA Analysis From Isolated Cardiomyocytes in the Molecular Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia

The main objective of this study is to assess if it is possible, at the end of endocardial voltage mapping, to accurately collect intact cardiomyocytes and to isolate high quality DNA allowing molecular testing of selected genes involved in arrhythmogenic right ventricular cardiomyopathy/dysplasia.

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations

QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, or arrhythmogenic right ventricular dysplasia), or inherited cardiomyopathies (hypertrophic, dilated, or

  • 0 views
  • 10 Mar, 2021
  • 1 location
None
An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China

This is a multi-omics research of Chinese cardiomyopathies patients, aiming to determine genetic risk factor and serial biomarkers of cardiomyopathies in diagnosis and prognosis.

  • 21 views
  • 22 Jan, 2021
  • 2 locations
None
DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research Studies

The DZHK TranslatiOnal Registry for CardiomyopatHies (DZHK TORCH) represents a unique resource of clinical data and high quality biological samples to enable innovative clinical and molecular studies on cardiomyopathies (CMP). As a multi-center German cardiomyopathy registry, TORCH has been prospectively admitting patients since December 2014. 2,300 patients were recruited as …

  • 0 views
  • 27 Jan, 2021
  • 1 location
None
Mayo AVC Registry and Biobank

Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous. Diagnosis and screening of blood-relatives is very difficult as the disease process can be subtle, but …

exercise tests
fibrillation
stress test
genetic condition
dilated cardiomyopathy
  • 228 views
  • 06 May, 2021
  • 2 locations
None
Molecular Genetic Screening and Identification of Congenital Arrhythmogenic Diseases

The aim of this study is the identification of familial congenital arrhythmogenic disorders and their clinical follow-up.

arrhythmogenic right ventricular dysplasia
hypertrophy
short qt syndrome
cardiomyopathy
syncope
  • 37 views
  • 07 Nov, 2020
  • 1 location
None
Pediatric Cardiomyopathy Mutation Analysis

The goal of this protocol is to obtain information from individuals with cardiomyopathy and from their families in order to elucidate the molecular genetics of this disorder. This will provide the basis for future genetic counseling as well as contribute to elucidating the biology of normal and abnormal cardiac function.

cardiomyopathy
  • 16 views
  • 25 Jan, 2021
  • 1 location
None
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic Inflammatory and Takotsubo Cardiomyopathy (MEMORY)

Manganese is a calcium analogue which actively enters viable cells with intact calcium-handling mechanisms and its uptake is evident by an increase in MRI-detectable T1 relaxivity of tissues. Mangafodipir is a novel manganese-based magnetic resonance imaging (MRI) contrast medium with unique biophysical properties that are ideal for application to cardiac …

MRI
angiography
cardiac mri
Accepts healthy volunteers
electrocardiogram
  • 27 views
  • 18 Oct, 2021
  • 1 location