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Found 855 clinical trials
Multiparametric Cardiac MRI in Patients Under CAR T-cell Therapy

Recently chimeric antigen receptor (CAR) T-cell therapy, a new class of chemo therapy, has gained regulatory approval for the treatment of diseases such as B-cell lymphoma. Known side effects include cytokine release syndrome, which has been described to lead to myocarditis, but larger studies exploring this relationship are currently lacking. …

  • 20 Jun, 2022
  • 1 location
The Natural History of Minimally Symptomatic Nonobstructing Calyceal Stones

The primary aim is to study the natural history of single-calyx asymptomatic nonobstructing stone disease. The Secondary aim is to determine the predictors of the need for intervention and of cure in such population.

urine culture
  • 24 Feb, 2022
  • 1 location
Evaluation of Relationship Between Preoperative Fibrinogen/Albumin Ratio and Morbidity After Hip Fracture Operations

Due to the aging of populations, hip fracture operations are increasing from year to year. This operations have many complications also high morbidity and the mortality. Population of this study is oldest old age patients who will have an operation because of hip fracture. The primary outcome of this study …

  • 22 Apr, 2022
  • 1 location
MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Variants

A large cohort of MRI scans from patients with pathogenic variants in the anoctamin 5 gene will be collected through an international collaboration to better describe muscle involvement.

  • 18 Nov, 2021
  • 1 location
Analysis of the Instestinal Microbiome of Patients With Transthyretin Amyloidosis (AMIAT)

Amyloidosis is a serious systemic disease. Cardiac involvement has a great impact on prognosis and can occur in its three main forms: acquired monoclonal light chain, hereditary transthyretinal and senile form. The physiopathogenesis basically results from the deposition of an abnormal protein (amyloid) with toxic properties to the myocyte. The …

Accepts healthy volunteers
  • 25 Mar, 2022
  • 1 location
Long Term Cardio-Vascular Risk Assessment in CKD and Kidney Transplanted Patients Following SARS-COV-2 (CARDIO SCARS)

The occurrence of novel coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), has offered an unmatched global challenge for the healthcare research community. SARS-CoV-2 infection is produced by binding to angiotensin-converting enzyme (ACE2), which among other sites is highly expressed in the endothelial cells of the …

  • 22 Mar, 2022
  • 1 location
Risk Factors and Predictors of Thrombosis in Myeloprolferative Neoplasms

To assess the clinical risk factors and predictable biomarkers of thrombotic complications in cases of philadelphia negative myeloproliferative disorders.

blood clot
  • 01 Mar, 2021
  • 1 location
Prognostic Value of Lung Ultrasound in Predicting Intensive Care Unit Length of Stay in Adult Cardiac Surgery

Being easy, bedside, non-expensive, noninvasive and radiation free, there has been a growing interest in the implementation of lung ultrasound in critical care management in the last decade, cardiac surgery was not an exception in both adult and pediatric surgeries Many predictors for open heart surgery outcomes have been studied …

heart surgery
cardiopulmonary bypass
bypass graft
  • 08 Oct, 2021
  • 1 location
Myval European Study of Myval THV System Implanted in Patients With Native Severe Aortic Valve Stenosis.

Myval European Study: A retrospective, multicentre, observational study in patients presenting with native severe aortic valve stenosis and treated with Myval Transcatheter Heart Valve System in real-world setting.

  • 02 Feb, 2021
  • 2 locations
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic Inflammatory and Takotsubo Cardiomyopathy (MEMORY)

Manganese is a calcium analogue which actively enters viable cells with intact calcium-handling mechanisms and its uptake is evident by an increase in MRI-detectable T1 relaxivity of tissues. Mangafodipir is a novel manganese-based magnetic resonance imaging (MRI) contrast medium with unique biophysical properties that are ideal for application to cardiac …

cardiac mri
heart failure
Accepts healthy volunteers
  • 18 Oct, 2021
  • 1 location