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Found 831 clinical trials
Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Perioperative Atrial Fibrillation After Noncardiac Surgery (ASPIRE-AF)

Multinational, investigator-initiated study of oral anticoagulation versus no anticoagulation for the prevention of stroke and other adverse cardiovascular events in patients with transient perioperative atrial fibrillation after noncardiac surgery and additional stroke risk factors.

dabigatran
rivaroxaban
atrial fibrillation
fibrillation
anticoagulants
  • 40 views
  • 24 Apr, 2022
  • 9 locations
Carotid Artery Implant for Preventing Stroke in Atrial Fibrillation Patients Taking Oral Anticoagulants (CAPTURE2)

This study will assess the safety and performance of the Vine Embolic Protection System (embolic filtering device) in atrial fibrillation (AF) patients on top of oral anticoagulants (OAC), and remain at high risk for stroke recurrence. All patients will receive bilateral implants in the common carotid arteries

noac
ischemic stroke
atrial fibrillation
fibrillation
anticoagulants
  • 3 views
  • 14 Feb, 2022
  • 9 locations
Monitoring Strategies for the Detection of Atrial Fibrillation in Patients With Cryptogenic Stroke

Randomized clinical trial comparing two monitoring strategies, the use of a 48-hour Holter (routine care branch) and an event recorder for 7 days (intervention branch). Patients admitted for cryptogenic stroke will be included. Enrollment and randomization of patients will be carried out during the index case hospitalization, while follow-up will …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Optimal Anticoagulation for Higher Risk Patients Post-Catheter Ablation for Atrial Fibrillation Trial (OCEAN)

substantially reduce the arrhythmia. AF is normally associated with an increased risk of stroke which in many patients can be prevented with appropriate blood thinner therapy. This trial will compare a strategy

arrhythmia
anticoagulant therapy
rivaroxaban
atrial fibrillation
fibrillation
  • 216 views
  • 07 Apr, 2022
  • 54 locations
Dabigatran for Mitral Stenosis Atrial Fibrillation

Atrial fibrillation (AF) is the most common sustained cardiac arrythmia encountered in clinical practice and patients suffer from this are at increased risk of ischemic stroke and systemic

  • 0 views
  • 28 Jan, 2021
  • 1 location
New Model of Integrated Care of Older Patients With Atrial Fibrillation in Rural China

This cluster randomization study aims to compare the people-centered integrated care versus usual care to improve outcome of older patients with atrial fibrillation in rural China.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Comparison of LAA-Closure vs Oral Anticoagulation in Patients With NVAF and Status Post Intracranial Bleeding.

Atrial fibrillation is the most common cardiac arrhythmia. In atrial fibrillation, there is a risk that clots can form in the heart, especially in the left atrium. If these clots come loose

arrhythmia
noac
anesthesia
atrial fibrillation
fibrillation
  • 0 views
  • 24 Jan, 2021
Amplatzer Amulet LAAO vs. NOAC (CATALYST)

The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control …

noac
ischemic stroke
electrocardiogram
embolism
left atrial appendage occlusion
  • 77 views
  • 22 Jul, 2022
  • 102 locations
CHAMPION-AF Clinical Trial (CHAMPION-AF)

The primary objective of this study is to determine if left atrial appendage closure (LAAC) with the WATCHMAN FLX device is a reasonable alternative to non-vitamin K oral anticoagulants in patients with non-valvular atrial fibrillation.

noac
hypertension
heart failure
fibrillation
transient ischemic attack
  • 130 views
  • 12 Jul, 2022
  • 152 locations
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG (PACES)

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying …

antiplatelet therapy
atrial fibrillation
thromboembolism
anticoagulants
ticagrelor
  • 112 views
  • 27 Apr, 2022
  • 44 locations