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Found 854 clinical trials
ABC-Scores for Reduction of Stroke and Mortality in Atrial Fibrillation - The ABC-AF Study (ABC-AF)

The primary study objective is to evaluate if personalized treatment by decision support, based on the biomarker-based risk prediction (ABC-scores) guided strategy, reduces the occurrence of the composite outcome of stroke or death in patients with atrial fibrillation. Approximately 6500 patients will be randomized 1:1 to ABC risk score guided …

fibrillation
anticoagulants
vitamin k
stroke
  • 8 views
  • 24 May, 2022
  • 1 location
Tailored vs. Anatomical Ablation Strategy for Persistent Atrial Fibrillation (Tailored-AF)

Atrial Fibrillation (AF) ablation is typically performed in predefined anatomic regions of the left atrium without attempting to identify patient-specific areas of interest. This procedure is referred to as Pulmonary Vein Isolation (PVI). The hypothesis in this Study is that a tailored ablation strategy targeting areas of spatio-temporal dispersion in …

anticoagulation therapy
heparin
pulmonary vein isolation
warfarin
heart failure
  • 4 views
  • 24 May, 2022
  • 23 locations
RedStroke - Reducing Europe's Stroke Incidence (RedStroke)

In the RedStroke study, the effect of a smartphone application in detecting Atrial Fibrillation (AF) will be assessed in a double-blind randomised controlled multicenter trial. Outpatients with an elevated risk for atrial fibrillation will be randomized to an intervention arm (app group) and to a standard-of-care arm (control group). Both …

vascular disease
electrocardiogram
holter monitor
stroke
  • 1 views
  • 29 May, 2022
  • 5 locations
Randomized Evaluation of Decision Support Interventions for Atrial Fibrillation (RED-AF)

This study will compare the effectiveness of the use of a Patient Decision Aid (PDA) and an Encounter Decision Aid (EDA) on Shared Decision Making (SDM) and health outcomes for at-risk participants with Atrial Fibrillation (AF) at 6 study sites. We hypothesize the combination of the PDA and EDA will …

  • 0 views
  • 03 Jun, 2022
  • 6 locations
Integrative Management of Patients With Atrial Fibrillation Via Hospital-Community-Family-Based Telemedicine (HCFT-AF) Program

Atrial fibrillation (AF) is one of the most common arrhythmias. Its repeated fluctuations in ventricular rate and irregular heart rhythm not only reduce exercise tolerance and quality of life

fibrillation
anticoagulant therapy
stroke
arrhythmia
anticoagulants
  • 5 views
  • 17 Feb, 2022
  • 1 location
iCLAS™ for Persistent Atrial Fibrillation

Clinical study to evaluate the safety and efficacy of the Adagio AF Cryoablation System (iCLAS™) in the ablation treatment of symptomatic, persistent atrial fibrillation (PsAF). Data will be used to support a pre-market application (PMA)

fibrillation
persistent atrial fibrillation
  • 4 views
  • 23 Mar, 2022
  • 20 locations
Precision Medicine in Ischemic Stroke and Atrial Fibrillation

The overall goal of this study is to minimize morbidity due to Atrial Fibrillation (AF). The specific objective is to develop and implement a rational and personalized approach to AF risk estimation that can inform management decisions with ischemic stroke. The investigators propose to develop a clinical AF risk estimation …

  • 0 views
  • 12 May, 2021
  • 1 location
Intensive Rhythm Monitoring to Decrease Ischemic Stroke and Systemic Embolism - the Find-AF 2 Study (Find-AF2)

Patients who have suffered a stroke are having an increased risk of having recurrent stroke in the future. This risk of stroke is increased by atrial fibrillation, which often "comes and goes" (called paroxysmal) and hence escapes routine diagnostics. The hypothesis of Find-AF 2 is that enhanced (evaluation in a …

anticoagulation therapy
holter monitor
embolism
electrocardiogram
atrial fibrillation
  • 0 views
  • 27 May, 2022
  • 50 locations
Arrhythmic Risk Stratification in Nonischemic Dilated Cardiomyopathy

Nonischemic dilated cardiomyopathy is a heterogeneous disease often associated with increased rates of sudden cardiac death. Although many algorithms have been proposed, risk stratification remains suboptimal, and implantable cardioverter-defibrillators are currently recommended only in patients with poor left ventricular function. However, most cases of sudden cardiac death occur at earlier …

  • 0 views
  • 09 May, 2021
  • 1 location
COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial Fibrillation

Atrial Fibrillation (AF) affects 200,000 Canadians and increases risk of stroke, morbidity and mortality. Having a stroke can affect a patient's ability to speak, eat, walk, work, care for themselves, and interact with others. Not only can it ruin one's life, but it can also be fatal. A stroke occurs …

anticoagulation therapy
warfarin
electrocardiogram
apixaban
stroke
  • 0 views
  • 11 Nov, 2021
  • 1 location