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Found 854 clinical trials
Aveir DR i2i Study

Prospective, non-randomized, multi-center, international study designed to evaluate the safety and effectiveness of the Aveir™ Dual-Chamber (DR) Leadless Pacemaker system.

  • 0 views
  • 13 Jun, 2022
  • 34 locations
Atrial Sensing Capability for Better Detection of Atrial Fibrillation

This prospective multi-center randomized controlled study aims to compare atrial fibrillation detection and inappropriate therapy according to activation of atrial sensing capability in patients with implantable cardioverter defibrillator.

implantable cardioverter-defibrillators
fibrillation
electrocardiogram
  • 0 views
  • 10 Oct, 2021
  • 28 locations
Prevention of Dysrhythmias on the Cardiac Intensive Care Unit - Does Maintenance of High-normal Serum Potassium Levels Matter (TIGHT-K)

The purpose of this study is to determine whether a strategy of maintaining serum potassium levels at ≥3.6 mEq/L is non-inferior to a strategy of usual treatment (≥4.5 mEq/L) on the occurrence of new onset atrial fibrillation after cardiac surgery (AFACS) in patients undergoing isolated coronary artery bypass graft (CABG) …

fibrillation
  • 0 views
  • 22 Apr, 2022
  • 1 location
Case-finding Study to Detect and Quantify Episodes of Absolute Arrhythmia Using an Automated Wearable Monitoring System

This feasibility study will develop and evaluate pathways to identify participants with wearable-detected absoulute Arrhythmia (AA) and to enable local study teams to contact them regarding

  • 0 views
  • 16 Mar, 2021
  • 2 locations
Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy (CLOSURE-AF)

The study goal is to determine the clinical benefit of percutaneous catheter-based left atrial appendage (LAA) closure in patients with non-valvular atrial fibrillation (NVAF) at high risk of stroke (CHA2DS2-VASc Score 2) as well as high risk of bleeding as compared to best medical care (including a [non-vitamin K] oral …

vitamin k
stroke
dabigatran
apixaban
left atrial appendage closure
  • 13 views
  • 28 Feb, 2022
  • 17 locations
Posterior Wall And Left Atrial Appendage Empiric Electrical Isolation for Non-Paroxysmal Atrial Fibrillation (PLEA)

The purpose of this study is to evaluate the safety and effectiveness of empirical posterior wall isolation (PWI), left atrial appendage electrical isolation (LAAEI) and coronary sinus isolation (CSI) when compared to pulmonary vein isolation (PVI) alone: PVI alone, PVI + PWI, PVI + PWI + LAAEI, PVI + PWI …

fibrillation
left ventricular dysfunction
paroxysmal atrial fibrillation
catheter ablation
pulmonary vein isolation
  • 18 views
  • 26 Feb, 2022
  • 10 locations
Reversal of Atrial Substrate to Prevent Atrial (RASTA AF)

A multi-center, randomized trial to examine the effect of aggressive risk factor control and arrhythmia trigger-based intervention on recurrence of atrial fibrillation.

stroke
arrhythmia
hypertension
persistent atrial fibrillation
heart failure
  • 25 views
  • 02 Mar, 2022
  • 1 location
Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF (BRAIN-AF)

This is a prospective, multicenter, randomized, double-blinded clinical trial exploring the efficacy and safety of rivaroxaban as compared to standard of care in reducing stroke, transient ischemic attack (TIA) and neurocognitive decline, in subjects with non-valvular AF and with low risk of stroke.

stroke
12 lead ECG
hypertension
heart failure
diabetes
  • 8 views
  • 22 Jan, 2022
  • 1 location
Appropriate Duration of Anti-Platelet and Thrombotic Strategy After 12 Months in Patients With Atrial Fibrillation Treated With Drug Eluting Stents

Atrial fibrillation patients with risk factors for stroke and systemic embolism require long-term anticoagulant therapy. Recently, non-vitamin K antagonist oral anticoagulant (NOAC) has shown their excellent safety and efficacy, and thus are widely accepted in clinical practice. Meanwhile, after percutaneous coronary intervention (PCI) using the drug-eluting stents due to coronary …

vitamin k
stroke
anticoagulant therapy
antiplatelet agents
apixaban
  • 0 views
  • 23 Sep, 2021
  • 1 location
The South-Norway Atrial Fibrillation Screening Study

Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder. The most serious common complication of AF is ischemic stroke.The aim of this study is to investigate the yield of

  • 0 views
  • 27 Jan, 2021
  • 1 location