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Found 53 clinical trials
Vascular Function in Health & Disease: Rehabilitation for Hypertension; Exercise and Skeletal Muscle Afferent Feedback

Many control mechanisms exist which successfully match the supply of blood with the metabolic demand of various tissues under wide-ranging conditions. One primary regulator of vasomotion and thus perfusion to the muscle tissue is the host of chemical factors originating from the vascular endothelium and the muscle tissue, which collectively …

chronic obstructive pulmonary disease
stress test
exercise test
nitric oxide
antioxidant
  • 0 views
  • 28 Oct, 2022
  • 1 location
Prehabilitation in Esophageal Surgery (PRESS) (PRESS)

Despite important clinical improvements, esophageal cancer surgery is still associated to a high rate of postoperative complications. Recent ERAS (Enhanced Recovery After Surgery) Society guidelines underline the possible role of prehabilitations' programs in reducing postoperative morbidity. In this trial, 200 patients, scheduled for esophageal cancer resection, will be randomly assigned …

  • 0 views
  • 08 Jul, 2022
  • 1 location
Effects of Nitrate-rich Beetroot Juice in Pregnant Women With High Blood Pressure (NITBEETPE)

BACKGROUND: Preeclampsia (PE) is a serious syndrome that affects 3-7% of all pregnant women. PE is characterized by hypertension and kidney problems after the 20th week of pregnancy and is associated with an increased risk of serious cardiovascular complications including death in both mother and fetus. The underlying disease mechanisms …

hypertension
renal function
Accepts healthy volunteers
cardiovascular complications
nitric oxide
  • 0 views
  • 25 Mar, 2022
  • 1 location
HaemoDYNAMICs in Primary and Secondary Hypertension

The primary aim of the present study was to examine the haemodynamic changes in primary hypertension and secondary hypertension (renal diseases, endocrine diseases, obesity-associated hypertension) with a non-invasive haemodynamic measurement protocol utilizing radial pulse wave analysis and whole-body impedance cardiography in both supine position and during head-up tilt. For comparison, …

nephropathy
hypertension
stenosis
aortic stenosis
  • 2 views
  • 28 Aug, 2021
  • 2 locations
The Clinical Value of the Nitric Oxide System Components in Asthma and COPD (ASCONO)

It is planned to conduct a study of nitric oxide metabolites (nitrates and nitrites), L-arginine, arginase-1, and asymmetric dimethylarginine in patients with bronchial asthma and chronic

  • 0 views
  • 13 May, 2022
  • 1 location
Investigating Predictive Factors of Diabetes Occurence After Duodenalpancreatectomy

patients will be subjected to incretin secretion (mixed meal), metabolic status (OGTT), insulin secretion characteristics (first and second phase responses), -cell insulin content evaluation (arginine

insulin
incretins
oral glucose tolerance test
  • 1 views
  • 13 Aug, 2021
  • 1 location
Hepatic Mitochondrial Function in Youth (MANGO)

Assess the impact of bariatric surgery on hepatic energy metabolism and glucose and insulin dynamics in obese youth

insulin
bariatric surgery
  • 4 views
  • 04 Oct, 2022
  • 1 location
Copeptin Kinetics in Critically Ill Patients With Posterior Reversible Encephalopathy Syndrome (XPRESSE)

XPRESSE is a multicenter observational prospective biomarker study in which critically ill patients with MRI-based PRES diagnosis will have copeptin kinetics from a daily blood sample for 6 days and a 3-month follow-up. This study aims to investigate the relationship between copeptin and PRES in order to establish the optimal …

  • 0 views
  • 12 Jul, 2022
  • 1 location
The CoAGulation Biomarkers and Atrial Fibrillation (COAG-AF) Pilot Study

The aim of the Correlation Of CoAGulation-Atrial Fibrillation (COAG-AF) study is to prove that an increase in pro-thrombotic biomarkers in AF is associated with an increase in AF burden. Secondary objectives of the study are the following: To investigate the impact of catheter ablation on serum pro-thrombotic biomarkers in patients …

catheter ablation
fibrillation
  • 0 views
  • 13 Oct, 2021
  • 1 location
Mother-to-Infant Transfer of Bacteriome Fungome Virome and Metabolome in Health and Crohn's Disease

Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are caused by the loss of mucosal tolerance towards the commensal microbiota resulting in inflammatory responses. Both CD and UC are difficult to manage clinically, and their incidences are increasing worldwide especially in newly industrialized countries. The etiology …

enteropathy
ulceration
colitis
crohn's disease
Accepts healthy volunteers
  • 0 views
  • 17 Nov, 2021
  • 1 location