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Found 53 clinical trials
A Multicenter Open-label Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With Somatostatin Receptor Positive Gastroenteropancreatic Neuroendocrine (GEP-NET) Tumors, Pheochromocytoma and Paragangliomas (PPGL)

This is a multicenter, open-label, single-arm study to evaluate the safety and dosimetry of Lutathera in adolescent patients 12 to <18 years old with somatostatin receptor positive GEP-NETs and PPGLs. The study will enroll at least 8 patients in the GEP-NET cohort and as many adolescents with PPGL as possible …

metastatic disease
dotatate
somatostatin
  • 0 views
  • 18 Oct, 2022
  • 13 locations
The HepatoPancreaticoBiliary Resection Arginine Immunomodulation (PRIMe) Trial (PRIMe)

This is a randomized controlled blinded superiority trial to evaluate the impact of perioperative immunosupplementation on immune function following resection for hepatopancreaticobiliary (HPB) malignancy.

adenocarcinoma
  • 0 views
  • 14 Jun, 2022
  • 2 locations
An Exploratory Study of Increased Preterm Arginine INTake (PAINT18) (PAINT18)

PAINT18 is a nutrition study focusing on the effect of arginine supplementation on immune function in preterm infants. The investigators will explore the effect of current intravenous

  • 0 views
  • 13 Apr, 2022
  • 1 location
Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial (STArT)

The trial of IV arginine therapy in children with Vaso-occlusive painful episodes (VOE) in sickle cell disease (SCD) is designed to further knowledge on efficacy and safety of the therapy.

arginine
opioid
  • 0 views
  • 24 Mar, 2022
  • 10 locations
An Exploratory Study of Arginine Supplementation and the Postoperative Immune REsponse (ASPIRE)

ASPIRE is a nutrition study focusing on the effect of arginine supplementation on immune function in postoperative infants. The investigators will explore the effect of current

  • 0 views
  • 06 Jun, 2022
  • 2 locations
The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction

The goal of the study is to examine the possible mechanisms of impaired cutaneous microvascular function through local heating along with administration of vasoconstrictors.

Accepts healthy volunteers
  • 0 views
  • 22 Mar, 2022
  • 1 location
Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease (R34 pK/PD)

The purpose of this study is to determine whether giving extra arginine to patients with sickle cell disease seeking treatment for vaso-occlusive painful events (VOE) will decrease pain scores

arginine
opioid
thalassemia
  • 0 views
  • 16 May, 2022
  • 2 locations
Novel Treatment of Advanced Hepatocellular Carcinoma (NTAHCC)

The purpose of this study is to evaluate the efficacy and safety of arginine hydrochloride combined with Levamisole in the treatment of patients with hepatocellular carcinoma.

antiviral therapy
g-csf
cancer
antiviral drugs
primary liver cancer
  • 1 views
  • 07 Feb, 2022
  • 1 location
Supplementing L-citrulline to Overweight Late Asthma oNset Phenotypes (SANDIA)

, particularly among females. This reduction of NO occurs through increased arginase activity and uncoupling of NO synthase (NOS), by accumulation of asymmetric di-methyl arginine (ADMA), which further lowers

Accepts healthy volunteers
  • 0 views
  • 21 Mar, 2022
  • 1 location
Phase IA/B Combination Study of ADI-PEG 20, Venetoclax and Azacitidine in Patients With Acute Myeloid Leukemia (AML)

Pegylated arginine deiminase (ADI-PEG 20) will be combined with venetoclax and azacitidine for treatment of subjects with previously treated or untreated with high risk factor acute myeloid

  • 0 views
  • 23 Oct, 2022
  • 1 location