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Found 21 clinical trials
Study to Evaluate Safety and Efficacy of Jaktinib in Adults With Alopecia Areata (AA)

This is a multi-center Phase 3 study to evaluate the safety and effectiveness of an investigational study drug (called Jaktinib) in adults (≥18 years and <65 years) who have 50% or greater scalp hair loss. The study is placebo-controlled, meaning that some patients entering the study will not receive active …

areata alopecia
  • 1 views
  • 28 May, 2022
  • 1 location
Study of DAXDILIMAB for the Treatment of Moderate-to-Severe Alopecia Areata

The purpose of this study is to assess the preliminary efficacy, safety, tolerability, PK, and PD of Daxdilimab in participants with moderate to severe AA, with ≥50% and ≤95% total scalp hair loss as defined by the SALT score at Screening and Day 1.

areata alopecia
treatment regimen
  • 5 views
  • 27 May, 2022
  • 3 locations
Evaluate the Efficacy and Safety of SHR0302 in Adult Patients With Severe Alopecia Areata

This is a multi-central, double-blind, randomized, parallel, placebo-controlled phase 3 study in adult subjects with severe alopecia areata (SALT≥50%). Approximately 330 adult patients will be enrolled into the study. Efficacy and safety of two doses of SHR0302 will be compared to placebo.

alopecia universalis
alopecia totalis
areata alopecia
  • 0 views
  • 09 Aug, 2022
  • 26 locations
Needle-free Delivery of Intralesional Triamcinolone for Pediatric Alopecia Areata

This is an interventional pilot study assessing the tolerability of needle-free delivery administration of ILTA with the Med-Jet as an alternative to conventional syringe and needle in patients with patchy pediatric alopecia areata. There will be a total of four (4) or five (5) visits necessary for study participation. The …

areata alopecia
  • 0 views
  • 23 Apr, 2022
  • 1 location
A Study to Evaluate the Efficacy and Safety of Rosnilimab (ANB030) in Treatment of Subjects With Moderate-to-Severe Alopecia Areata (AZURE)

Efficacy and safety of rosnilimab (ANB030) in subjects with moderate-to-severe Alopecia Areata

areata alopecia
  • 24 views
  • 23 May, 2022
  • 16 locations
DPCP for the Treatment of Alopecia Areata

This is an open labeled study to determine the response and characteristics, safety and efficacy, of the proprietary DPCP ointment composition as a topical immunotherapeutic agent for the treatment of extensive alopecia areata.

alopecia
areata alopecia
diphenylcyclopropenone
  • 595 views
  • 12 May, 2022
  • 1 location
Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata

The purpose of this study is to evaluate the safety and efficacy of etrasimod monotherapy (2 milligrams [mg] and 3 mg) in participants with moderate-to-severe alopecia areata (AA).

areata alopecia
  • 435 views
  • 15 Mar, 2022
  • 27 locations
A Study With Jaktinib Hydrochloride Cream Applied Topically to Subjects With Alopecia Areata

This study includes a dose escalation part(phase I) and a dose extension part(phase II).

areata alopecia
  • 51 views
  • 01 Apr, 2021
  • 1 location
Improving Disease Severity in Alopecia Areata, Polymorphous Light Eruption, and Psoriasis Patients With Lumiton Technology

Phototherapy, including ultraviolet B (UVB) and ultraviolet A (UVA) light, has been used to treat a number of dermatologic conditions. Psoriasis is one of the most common conditions treated with phototherapy, in which phototherapy is often indicated for extensive disease with contraindications for other systemic treatments. The mechanism of action …

  • 0 views
  • 16 Sep, 2022
A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Background Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune system makes a mistake and attacks the body. Some people with APECED have a type of hair loss called alopecia areata (AA). No drugs are approved to treat AA. Objective …

Accepts healthy volunteers
graft-versus-host disease
bilateral tubal ligation
ruxolitinib
blood tests
  • 30 views
  • 20 Sep, 2022
  • 1 location