aptt Clinical Research Trials

A Study to Assess the Reversal of the Anticoagulant Effects of JNJ-70033093 by 4-Factor Prothrombin Complex Concentrate (4F-PCC) (Part 1) and Recombinant Human Factor VIIa (rFVIIa) (Part 2) in Healthy Participants

(rFVIIa) in healthy participants as measured by changes from baseline of the coagulation testing parameters (activated partial thromboplastin time [aPTT] and thrombin generation assay [TGA]).

0 views
19 Feb, 2021
1 location

The Effect of a Levonorgestrel-releasing Intrauterine Device (IUD) Versus a Copper Containing IUD on Risk of Blood Clots

), factor VIIIc, activated partial thromboplastin time (aPTT) and activated partial thromboplastin time plus activated protein C (aPTT + APC). Both groups will undergo a GYN exam with screening

thrombosis

levonorgestrel

d-dimer

protein c

copper

131 views
07 Nov, 2020
1 location

Valproic Acid and Dihydroergotamine as Abortive Therapy in Pediatric Migraine

The objective of this study is to compare clinical efficacy and tolerability of valproic acid (VPA) therapy versus dihydroergotamine (DHE) as abortive therapy in pediatric migraine.

0 views
24 Jan, 2021
1 location

Heparin Anticoagulation in Septic Shock

This study is a pragmatic open-label international randomized trial comparing therapeutic dose intravenous unfractionated heparin (UFH) to standard care venous thromboprophylaxis in patients diagnosed with septic shock.

renal injury

systolic blood pressure

mechanical ventilation

epinephrine

urine output

121 views
04 Feb, 2021
50 locations

Mesoglycan (Prisma ) Versus Placebo in Secondary Prevention of the Superficial Venous Thrombosis

The objective of the study is to demonstrate the superiority of the mesoglycan (Prisma), compared to placebo, in reducing the incidence of thromboembolic complications (relapse / extension of superficial venous thrombosis (SVT), deep venous thrombosis (DVT), pulmonary embolism (PE)) in patients who have completed the cycle of therapy of the …

9 views
24 Jan, 2021
1 location

Efficacy And Safety Of Unfractionated Heparin In Patients With Cardiovascular Surgery Using Cardiopulmonary Bypass

surgery, based on measurements of markers of coagulation ACT, aPTT, anti-Xa heparin levels and the excessive blood loss (hemorrhage) after the end of surgery.

30 views
08 Nov, 2020
1 location

A Phase 3 Open-label Interventional Study of an Intravenous Recombinant Coagulation Factor VIII Fc-von Willebrand Factor-XTEN Fusion Protein Efanesoctocog Alfa (BIVV001) in Patients With Severe Hemophilia A

the 1-stage activated partial thromboplastin time (aPTT) and 2-stage chromogenic FVIII activity assays

severe haemophilia a

antihemophilic factor

von willebrand's disease

treatment regimen

von willebrand factor

13 views
27 Feb, 2021
3 locations

Low Dose Catheter Directed Thrombolysis for Acute Pulmonary Embolism

(APTT) is 2-2.5 of reference value) or CDT (4mg alteplase (r-tPA) per catheter, infusion over 2 hours) in an open label, outcome assessor blinded, randomized, controlled trial. Primary efficacy endpoint

angiography

computed tomography angiography

alteplase

heparin

acute pulmonary embolism

1 views
24 Jan, 2021
1 location

Long-term Safety and Efficacy of Efanesoctocog Alfa (BIVV001) in Previously Treated Patients With Hemophilia A

evaluate the safety and tolerability of BIVV001 treatment. To assess the PK of BIVV001 based on the one stage activated partial thromboplastin time (aPTT) and two-stage chromogenic FVIII activity

0 views
26 Feb, 2021
1 location

Assessment of the Neuro-glio-epithelial Unit (NGEU) in Biopsies Taken During Peroral Endoscopic Myotomy (POEM) for Achalasia: a Feasibility and Safety Study.

, APTT, serum electrolytes and CRP level. Finally, at each post-POEM phone calls, the occurrence of adverse events will be reported. Our primary hypothesis is that the analysis of mucosal and

serum electrolytes

motility disorder

esophageal motility

electrolytes

peroral endoscopic myotomy

10 views
26 Jan, 2021
1 location

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Found 27 clinical trials