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Found 25 clinical trials
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A 26-Week, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Daily Administration of AC-1204 in Participants With Mild to Moderate Alzheimer's Disease (AD) With an Optional 26-Week Open Label Extension

A 26-Week, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Daily Administration of AC-1204 in Participants With Mild to Moderate Alzheimer's Disease (AD) With an Optional 26-Week Open Label Extension

  • 109 views
  • 08 Dec, 2020
  • 1 location
None
Exercise for Brain Health in the Fight Against Alzheimer's Disease

, cognition, and physical function in cognitively healthy and physically inactive older adults (ages 60-80). Apolipoprotein E epsilon4 (APOE-4) allele carriers are known to be at substantially greater risk

  • 41 views
  • 26 Jan, 2021
  • 1 location
None
Epileptiform Activity During REM Sleep in Alzheimer's Disease

scans) and in the case of patients, the phenotype of the Apolipoprotein E(ApoE) gene.

mini-mental state examination
mental state examination
apolipoprotein e
polysomnography
  • 0 views
  • 07 Aug, 2021
  • 1 location
None
Predicting Postoperative Delirium Using EEG Genetics and Neurobiomarkers of Cerebral Injury

(EEG), under general anesthesia, is associated with the occurrence of POD, and whether specific patterns worrelate with the patient's preoperative cognitive status. As apolipoprotein E (APOE

cerebral injury
intraoperative eeg
cardiopulmonary bypass
apolipoprotein
heart surgery
  • 0 views
  • 29 Sep, 2021
  • 1 location
None
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism

The aim of this study is to identify new targets in cholesterol metabolism thanks to a genetically-based strategy.

  • 0 views
  • 07 Aug, 2021
  • 1 location
None
Multi-modal Neuroimaging in Alzheimer's Disease

Alzheimer's disease (AD) is a major public health problem due to its socio-economic weight. An early diagnosis of AD is urgently needed as it would constitute a determinant breakthrough from a social, financial and research standpoints. Therefore, the investigators need predictive markers of AD, and neuroimaging is a particularly promising …

mini-mental state examination
apolipoprotein e
early diagnosis
  • 7 views
  • 08 Nov, 2020
  • 1 location
None
Statins In Intracerbral Hemorrhage

to continue/discontinue statins should be influenced by an individual's Apolipoprotein-E (APOE) genotype.

  • 0 views
  • 30 Jul, 2021
None
Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain

High fat feeding (HFF) increases the risk of Alzheimer's disease (AD) but individuals who carry the AD risk gene E4 paradoxically improve after acute HFF. The investigators propose to further study this phenomenon with a clinical study to assess cerebral blood flow which can be measured by a technique called …

apolipoprotein e
alzheimer's disease
  • 5 views
  • 20 Jun, 2021
  • 1 location
None
Temporal Relations and Exercise Interventions of Various Gait and Cognitive Domains in Older Adults

endothelial growth factor (VEGF) and expression of the apolipoprotein E (APOE) 4 allele parallel changes in gait characteristics and cognitive functions after the intervention will be examined.

  • 0 views
  • 16 Jun, 2021
  • 1 location
None
Brain Energy for Amyloid Transformation in Alzheimer's Disease Study

The Brain Energy for Amyloid Transformation in AD (Alzheimer's disease) or BEAT-AD study will compare the effects of a ketogenic low-carbohydrate diet and a low-fat diet in adults with mild cognitive impairment. The data collected will help determine whether diet interventions induce changes in cognitive function, cerebral blood flow, and …

amyloid
cognitive assessment
alzheimer's disease
mild cognitive impairment
cognitive impairment
  • 9 views
  • 09 Jul, 2021
  • 1 location