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Found 60 clinical trials
Featured trial
A Study of the Prevalence of Apolipoprotein L1 (APOL1) Alleles Among Individuals With Proteinuric Kidney Disease Who Are of Recent African Ancestry or Geographic Origin

A Study of the Prevalence of Apolipoprotein L1 (APOL1) Alleles Among Individuals With Proteinuric Kidney Disease

diabetes
  • 1 views
  • 29 Jul, 2021
  • 1 location
Featured trial
Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis

Background: Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that becomes worse over time. There is currently no effective treatment for it. Researchers want to study the disease and learn new ways to treat it. Objectives: To discover new pathways that are involved in pulmonary fibrosis. To develop new …

chest x-ray
ct scan
walk tests
chest ct
x-rays
  • 178 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A 26-Week, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Daily Administration of AC-1204 in Participants With Mild to Moderate Alzheimer's Disease (AD) With an Optional 26-Week Open Label Extension

A 26-Week, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Daily Administration of AC-1204 in Participants With Mild to Moderate Alzheimer's Disease (AD) With an Optional 26-Week Open Label Extension

  • 171 views
  • 08 Dec, 2020
  • 1 location
Phase 2/3 Adaptive Study of VX-147 in Adults With APOL1- Mediated Proteinuric Kidney Disease

The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics (PK) of VX-147 in participants aged 18 years and older with apolipoprotein L1 (APOL1)-mediated

  • 0 views
  • 12 Jul, 2022
  • 28 locations
Epileptiform Activity During REM Sleep in Alzheimer's Disease (EREMAD)

scans) and in the case of patients, the phenotype of the Apolipoprotein E(ApoE) gene.

mental state examination
polysomnography
Accepts healthy volunteers
apolipoprotein e
mini-mental state examination
  • 0 views
  • 23 Jan, 2022
  • 1 location
Exercise for Brain Health in the Fight Against Alzheimer's Disease

, cognition, and physical function in cognitively healthy and physically inactive older adults (ages 60-80). Apolipoprotein E epsilon4 (APOE-4) allele carriers are known to be at substantially greater risk

Accepts healthy volunteers
  • 165 views
  • 16 Feb, 2022
  • 1 location
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism (HYPOCHOL)

The aim of this study is to identify new targets in cholesterol metabolism thanks to a genetically-based strategy.

  • 0 views
  • 24 Feb, 2022
  • 1 location
Statins In Intracerbral Hemorrhage

to continue/discontinue statins should be influenced by an individual's Apolipoprotein-E (APOE) genotype.

  • 0 views
  • 30 Jul, 2021
Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain

High fat feeding (HFF) increases the risk of Alzheimer's disease (AD) but individuals who carry the AD risk gene E4 paradoxically improve after acute HFF. The investigators propose to further study this phenomenon with a clinical study to assess cerebral blood flow which can be measured by a technique called …

apolipoprotein e
alzheimer's disease
Accepts healthy volunteers
  • 5 views
  • 24 Jan, 2022
  • 1 location
Influence of Glycaemic Balance on the Ability of Apolipoprotein C1 to Inhibit Cholesteryl Ester Transfer Protein in Type-1 Diabetes Patients (ApoC1)

In type-1 diabetes patients, bad cholesterol tends to accumulate because apoC1 function is slowed down. ApoC1 is a protein whose role is to diminish the activity of CETP, another protein that regulates cholesterol transfer in the body. The aim of this study is to determine whether it is possible to …

Accepts healthy volunteers
  • 0 views
  • 29 May, 2022
  • 2 locations