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Found 72 clinical trials
Antithrombotics' Therapeutic Optimization in Hospitalized Patients Using Physiologically- and Population-based Pharmacokinetic Modeling

The main goal of the OptimAT study main goal is to validate a PBPK model for 3 direct oral anticoagulants (rivaroxaban, apixaban, dabigatran) and 3 P2Y12 inhibitors (clopidogrel, ticagrelor

  • 0 views
  • 22 Jan, 2021
  • 1 location
Real-life Clinical Outcomes of Direct Oral Anticoagulants (MACACOD)

MACACOD is a clinical record in the usual clinical practice of direct oral anticoagulants (dabigatran, rivaroxaban, apixaban and edoxaban). Design: single-center, observational, prospective

apixaban
anticoagulants
edoxaban
rivaroxaban
dabigatran
  • 2 views
  • 24 Jan, 2021
  • 1 location
Atrial Fibrillation Research Database

All patients with atrial fibrillation who are treated with vitamin-k antagonists (warfarin, phenprocoumon) or non vitamin K oral anticoagulants (Dabigatran, Rivaroxaban, Apixaban, Edoxaban) in

anticoagulants
phenprocoumon
rivaroxaban
dabigatran
apixaban
  • 2 views
  • 24 Jan, 2021
  • 2 locations
Non-Interventional Study on Effectiveness of Elxaban Tab. in Patients With Non-valvular Atrial Fibrillation

apixaban) who visit hospital. The purpose is to analyze bleeding (major bleeding, minor bleeding), stroke, systemic embolism, death, other clinical events (acute myocardial infarction, pulmonary embolism

apixaban
transient ischemic attack
embolism
fibrillation
infarct
  • 3 views
  • 23 Jan, 2021
  • 1 location
Registry of Patients Prescribed Anticoagulation

" agents: warfarin and heparinoids and the newer direct oral anticoagulants (DOACs) such as rivaroxaban, dabigatran, apixaban, and edoxaban.

  • 17 views
  • 25 Jan, 2021
  • 1 location
Biological Collection and Registry of Patients Who Will Have a TAVR (Transcatheter Aortic Valve Replacement) Intervention

A sample of plasma and whole blood will be obtained at 4 time points (pre-procedural, early post-procedural, at hospital discharge and during an eventual visite at 3 or 6 months post-procedural). Test for platelet reactivity (LTA, light transmittance aggregometry and Elisa PRI, Platelet reactivity index), multimeric VWF (von Willebrand factor) …

aortic valve replacement
  • 1 views
  • 22 Jan, 2021
Benefit/Risk in Real Life of New Oral Anticoagulants and Vitamin K Antagonists in Patients Aged 80 Years and Over

The aim of the study is to compare, in real life, the risk benefit (including both major bleeding and thrombotic events (TE) and death from any cause) associated with direct oral anticoagulants (DOA) and with anti vitamin K (VKA) in older adults ( 80 years) suffering from non valvular atrial …

anticoagulants
rivaroxaban
dabigatran
vitamin k antagonist
apixaban
  • 3 views
  • 23 Jan, 2021
  • 2 locations
Baseline Concentration of Direct Oral Anticoagulant and Incidence of Adverse Event Measure And See (MAS)

The MAS Study is an observational, multicentre, prospective cohort study in Non valvular Atrial fibrillation (NVAF) patients treated with one of the direct oral anticoagulants (DOACs) available in Italy for NVAF patients. The general aim is to deepen the knowledge of DOAC treatment in NVAF patients, by measuring the plasma …

fibrillation
anticoagulants
anticoagulation therapy
  • 1 views
  • 25 Mar, 2021
  • 1 location
Predictive Factors for Response to New Oral Anticoagulants in the Treatment of Non-valvular Atrial Fibrillation..

Post-authorization observational, prospective, follow-up study of a cohort of patients with non-valvular atrial fibrillation who are treated with direct oral anticoagulants (DOACs) to evaluate the clinical course (occurrence of stroke, major bleeding and mortality) and its correlation with clinical, pharmacokinetic (plasma concentrations), pharmacodynamic (haemostatic) and pharmacogenetic factors.

anticoagulants
rivaroxaban
embolism
dabigatran
apixaban
  • 17 views
  • 26 Jan, 2021
  • 6 locations
Novel Oral Anticoagulants in Stroke Patients

The present study will monitor and explore acute neurovascular emergencies in patients treated with NOACs compared to those under treatment with VKAs. The primary aims of this study are: (1) To investigate characteristics, management and outcome of intracranial hemorrhage (ICH) in patients treated with NOAC compared to VKA. (2) To …

anticoagulants
intracranial hemorrhage
stroke
  • 24 views
  • 24 Jan, 2021
  • 1 location