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Found 72 clinical trials
A Prospective Multi-dose Study of Apixaban in Subjects With Nephrotic Syndrome

This phase I study is a single arm, multi-dose study that will evaluate steady-state apixaban pharmacokinetics (PK) and pharmacodynamics (PD) in subjects with Nephrotic Syndrome (NS) vs healthy

proteinuria
hypoalbuminemia
mammogram
apixaban
chronic kidney disease
  • 0 views
  • 22 May, 2021
  • 1 location
Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients

physicians decide the best treatment plan for these patients. The study drug, apixaban, is a new type of orally-taken blood thinner that has been shown to be effective and safe for prevention and

  • 0 views
  • 11 Mar, 2021
  • 1 location
Pharmacokinetics of Apixaban in Patients With Short Bowel Syndrome Requiring Long Term Parenteral Nutrition

resection. It remains unclear to what extent apixaban exposure is impacted in SBS.Therefore this study tries to investigate the pharmacokinetics (PK) of apixaban in adult patients with SBS requiring long

  • 0 views
  • 08 May, 2021
  • 1 location
Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver Cirrhosis

The aim of this study is to investigate the pharmacokinetic and pharmacodynamic parameters of rivaroxaban and apixaban in patients with compensated liver cirrhosis (Child-Pugh class A and B

  • 0 views
  • 31 May, 2021
  • 1 location
Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients.

This study will evaluate the efficacy and safety of apixaban 2.5 mg twice daily plus aspirin compared to the standard treatment (clopidogrel plus aspirin) in patients with critical limb ischemia

stenosis
endovascular intervention
clopidogrel 75 mg
clopidogrel
endovascular procedure
  • 0 views
  • 26 Apr, 2021
  • 1 location
Evaluation of the Use of Apixaban in Prevnetion of Thromboembolic Disease in Patients With Myeloma Trated With iMiDs

with IMiDs and require thromboprophylaxis for 6 months, using an oral anti-Xa anticoagulant, Apixaban, in a preventive scheme, 2.5 mg x2/day

prednisone
apixaban
lenalidomide
thalidomide
dexamethasone
  • 45 views
  • 07 Nov, 2020
  • 14 locations
Compare Apixaban and Vitamin-K Antagonists in Patients With Atrial Fibrillation (AF) and End-Stage Kidney Disease (ESKD)

The Study is an open-labeled, randomized controlled trial, phase IIIb. Its objective is to assess the safety of the factor Xa inhibitor apixaban versus the vitamin-K antagonist (VKA

electrocardiogram
embolism
stroke
apixaban
chronic haemodialysis
  • 6 views
  • 06 May, 2021
  • 3 locations
Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamic of Oral Anticoagulants (Rivaroxaban Apixaban) in Health Volunteers

Background Rivaroxaban and apixaban are blood thinners. People with HIV may need to take them to treat or prevent blood clots. The anti-HIV drug darunavir (DRV

fasting
blood test
body mass index
  • 6 views
  • 27 Apr, 2021
  • 1 location
Causes and Prevention of Thromboembolic Disease in Nephrotic Syndrome

The study aims to describe the biochemical coagulation profile and investigate the effect of Low molecular weight heparin and Apixaban on this profile in patients with nephrotic syndrome.

  • 0 views
  • 30 Apr, 2021
  • 1 location
Improved Adherence With Extended Venous Thromboembolism Prophylaxis After Major Cancer Surgery

adherence to extended deep vein thrombosis prophylaxis (DVT) with the direct oral anticoagulant apixaban on the background of historical data from the investigator's center on low-molecular-weight heparin

  • 0 views
  • 07 Mar, 2021
  • 2 locations