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Found 65 clinical trials
Trial of Apixaban vs Warfarin in Reducing Rate of Cognitive Decline Silent Cerebral Infarcts and Cerebral Microbleeds in Patients With Atrial Fibrillation

The investigators' central hypothesis is that in patients with atrial fibrillation, anticoagulation with Apixaban reduces the rate of decline in cognitive function, when compared to Warfarin

  • 0 views
  • 22 Jan, 2021
  • 1 location
Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamic of Oral Anticoagulants (Rivaroxaban Apixaban) in Health Volunteers

Background Rivaroxaban and apixaban are blood thinners. People with HIV may need to take them to treat or prevent blood clots. The anti-HIV drug darunavir (DRV

fasting
body mass index
blood test
  • 6 views
  • 26 Jan, 2021
  • 1 location
Treatment of Intracerebral Hemorrhage in Patients on Non-vitamin K Antagonist

Novel, non-vitamin K antagonist oral anticoagulants (NOAC) target selected players in the coagulation cascade as the direct thrombin inhibitor dabigatran and the factor Xa-inhibitors apixaban

noac
apixaban
hematoma
rivaroxaban
anticoagulants
  • 19 views
  • 25 Jan, 2021
  • 1 location
Impact of Early Debriefing and Enhanced Educative Components on Direct Oral Anticoagulant Adherence After Venous Thromboembolism.

and educative components added to a standardized visit one month after an acute VTE has the potential to improve patient's adherence to APIXABAN therapy at 6 months of follow-up.

apixaban
anticoagulation therapy
anticoagulants
  • 1 views
  • 26 Jan, 2021
  • 15 locations
Coordination of Oral Anticoagulant Care at Hospital Discharge

Oral anticoagulants (OACs - warfarin, dabigatran, rivaroxaban, apixaban and edoxaban) are the very top cause of serious drug-related harm. More than 7 million prescriptions are dispensed

  • 0 views
  • 02 Feb, 2021
  • 1 location
Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery

Prospective, open-label clinical trial to evaluate the efficacy and safety of andexanet alfa patients who require urgent surgery that have been anticoagulated with the FXa (activated factor X) inhibitors.

enoxaparin
  • 0 views
  • 24 Jan, 2021
  • 2 locations
Avoiding Anticoagulation After IntraCerebral Haemorrhage

Randomised controlled trials (RCTs) demonstrate a substantial benefit from oral anticoagulant drugs for the prevention of stroke and systemic embolism in non-valvular atrial fibrillation (AF). However, these RCTs excluded patients with prior intracerebral haemorrhage (ICH). Therefore, guidelines are unable to recommend whether oral anticoagulant drugs, in particular non-vitamin K antagonist …

apixaban
anticoagulation therapy
intracerebral hemorrhage
stroke
brain ct
  • 0 views
  • 25 Jan, 2021
  • 2 locations
TXA and Corona Virus 2019 (COVID19) in Outpatients

A controlled trial of the drug tranexamic acid (TXA) in outpatients who were recently diagnosed with COVID-19. It is hypothesized that TXA will reduce the infectivity and virulence of the virus.

covid-19
  • 62 views
  • 24 Feb, 2021
  • 1 location
Efficacy of a Didactic Intervention in Anticoagulated Patients (TAOPE Study)

Background: Oral anticoagulant drugs represent an essential tool in thrombo-embolic events prevention. Most used are vitamin K antagonists (VKA), which plasma level is monitored measuring prothrombin time using the International Normalized Ratio. If it takes values out of recommended range, the patient will have a higher risk of suffering from …

  • 1 views
  • 22 Jan, 2021
  • 2 locations
Safety and Efficacy of Apixaban in Very Old Geriatric Subjects (> 80 Years) With Atrial FIbrillation in a Prospective reAl World Study;

Atrial fibrillation (AF) newly treated with Apixaban. Moreover, in this geriatric population the adequacy of Apixaban dosage and events (bleeding and stroke) will be assessed.

  • 0 views
  • 26 Jan, 2021
  • 1 location