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Found 72 clinical trials
FREEDOM COVID-19 Anticoagulation Strategy

Coronavirus Disease (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has led to unprecedented morbidity and mortality in the modern era. To date, nearly 13 million people have contracted COVID-19, leading to more than 550,000 deaths worldwide. As the number of affected individuals continues to climb, effective strategies for …

fever
oximetry
respiratory distress
coronavirus infection
covid-19
  • 20 views
  • 19 Feb, 2021
  • 20 locations
Appropriate Duration of Anti-Platelet and Thrombotic Strategy After 12 Months in Patients With Atrial Fibrillation Treated With Drug Eluting Stents

Atrial fibrillation patients with risk factors for stroke and systemic embolism require long-term anticoagulant therapy. Recently, non-vitamin K antagonist oral anticoagulant (NOAC) has shown their excellent safety and efficacy, and thus are widely accepted in clinical practice. Meanwhile, after percutaneous coronary intervention (PCI) using the drug-eluting stents due to coronary …

embolism
vitamin k antagonist
anticoagulants
noac
anticoagulation therapy
  • 0 views
  • 25 Jan, 2021
  • 1 location
Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery

Prospective, open-label clinical trial to evaluate the efficacy and safety of andexanet alfa patients who require urgent surgery that have been anticoagulated with the FXa (activated factor X) inhibitors.

enoxaparin
  • 0 views
  • 19 Jul, 2021
  • 64 locations
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying …

vitamin k antagonist
aspirin
anticoagulation therapy
rivaroxaban
thromboembolism
  • 112 views
  • 26 Jul, 2021
  • 80 locations
Study of Apixaban in Patients Receiving Hemodiafiltration

inhibitors (dabigatran), and activated factor X inhibitors (rivaroxaban, apixaban, edoxaban), do not require regular monitoring, but their plasma concentrations are altered with the deterioration of the

anticoagulants
anticoagulation therapy
rivaroxaban
apixaban
dabigatran
  • 0 views
  • 19 Jul, 2021
  • 1 location
Apixaban for Routine Management of Upper Extremity Deep Venous Thrombosis

This study will assess the safety and effectiveness of a drug called apixaban for the treatment of upper extremity deep vein thrombosis (UEDVT) and clinically important bleeding. Subjects will

deep vein thrombosis
venous thrombosis
anticoagulants
drug test
thrombosis
  • 212 views
  • 23 Jan, 2021
  • 2 locations
Apixaban vs Enoxaparin Following Microsurgical Breast Reconstruction-An RCT

Subcutaneous enoxaparin is currently the gold standard for VTE chemoprophylaxis. However, the efficacy of chemoprophylaxis with subcutaneous enoxaparin is affected by patient-level factors, thus, resulting in VTE events despite guideline-compliant prophylaxis. A population at particular risk is the growing number of patients who undergo autologous breast reconstruction. Direct oral anticoagulants …

enoxaparin 40mg/0.4ml prefilled syringe
anticoagulants
apixaban 2.5 mg
apixaban
enoxaparin
  • 0 views
  • 26 Jan, 2021
  • 1 location
Oral Anticoagulant Apixaban for Treatment of Venous Thromboembolism

Patients who have developed a venous thrombosis will receive apixaban to treat and prevent a secondary thromboembolism.

direct bilirubin
anticoagulants
thrombosis
heparin
renal function
  • 2 views
  • 26 Jan, 2021
  • 1 location
RAMBLE - Rivaroxaban vs. Apixaban for Heavy Menstrual Bleeding

A large proportion of women with menstruating potential with newly diagnosed VTE or atrial fibrillation, treated with apixaban will have less menstrual blood loss than patients randomized to

anticoagulation therapy
rivaroxaban
anticoagulants
apixaban
  • 210 views
  • 23 Jan, 2021
  • 2 locations
Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver Cirrhosis

The aim of this study is to investigate the pharmacokinetic and pharmacodynamic parameters of rivaroxaban and apixaban in patients with compensated liver cirrhosis (Child-Pugh class A and B

  • 0 views
  • 31 May, 2021
  • 1 location