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Found 31634 clinical trials
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Characterizing Fatigue Experienced by Cancer Patients Receiving Primary Treatment and Cancer Survivors

Background Fatigue is a common side effect of cancer and its treatment. Up to 96% of patients with cancer have fatigue. The cause of fatigue in people with cancer or those receiving treatment is poorly understood, making fatigue hard to treat. More research is necessary to understand why cancer patients …

depression
primary cancer
metastasis
cancer treatment
fatigue symptoms
  • 5 views
  • 17 Aug, 2021
  • 1 location
None
Biomarkers in Parkinsonian Syndromes

Parkinson disease (PD), multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) are neurodegenerative disorders. PD and MSA are alpha-synucleinopathies, which are characterized by the abnormal accumulation of alpha-synuclein, while tau protein accumulates in PSP. The development of biological markers for the diagnosis and prognosis in PD, MSA and PSP …

supranuclear palsy
parkinsonism
depression
synucleinopathy
neurodegenerative disorders
  • 248 views
  • 24 Jan, 2021
  • 3 locations
None
Non-Anesthetized Plexus Technique for Infant (BPBP) MRI Evaluation

The investigators are studying the ability of a novel rapid magnetic resonance imaging (MRI) protocol to provide more accurate and earlier information about whether an infant with brachial plexus birth palsy will require nerve surgery.

nerve surgery
  • 4 views
  • 26 Jan, 2021
  • 2 locations
None
Airway Clearance Therapy on Hyperpolarized 129Xenon and MRI

This is an observational cohort study building on an existing protocol at our institution recruiting CF patients who are 6-21 years old with one or two copies of the F508del CFTR mutation. That existing protocol seeks to enroll a total of 38 subjects; it includes three to four (three scheduled, …

lung clearance index
spirometry
  • 4 views
  • 25 Jan, 2021
  • 1 location
None
Muscle Accrual and Function in Cystic Fibrosis-Impact of Glucose Intolerance

This study will investigate the link between glucose abnormalities and elements critical to muscle function including mass, composition and energy metabolism. the primary goal of the study is to determine whether Cystic Fibrosis (CF) disease is associated with muscle dysfunction, especially in the presence of glucose intolerance. This is a …

insulin
allergic bronchopulmonary aspergillosis
fibrosis
diabetes
forced expiratory volume
  • 12 views
  • 15 Feb, 2021
  • 2 locations
None
Bacterial Transmission In Utero and IBD Risk

Inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), are caused by the loss of mucosal tolerance towards the commensal microbiota resulting in inflammatory responses. Identifying intestinal bacteria in mother and newborn of both IBD and Control groups allow us to understand the change of bacterial composition human …

microbiota
hyperemesis gravidarum
colitis
ulceration
colectomy
  • 8 views
  • 22 Jan, 2021
  • 1 location
None
Medication Adherence Research in COPD Patients

Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death, affects over 24 million people in the US and is the leading cause of disability with projected healthcare costs at almost $50 billion. The goal of this study is to identify novel and potentially powerful targets for behavioral …

forced expiratory volume
  • 78 views
  • 22 Aug, 2021
  • 2 locations
None
Instacare - Rapid ART Initiation Among Persons With HIV and Out of Care

This study aims to evaluate two ways to help people re-engage with healthcare. The first is to assess if providing HIV treatment on the first visit (or within 1 week) can help people re-engage with care and ultimately stay in care after 24 and 48 weeks. It will also assess …

HIV Vaccine
HIV Infection
  • 0 views
  • 02 Jul, 2021
  • 2 locations
None
Effect of Cladribine Treatment on Microglial Activation in the CNS

To evaluate the effect of cladribine treatment on microglial activation with conventional MRI, QSM-post processing and TSPO-PET imaging in late stage relapsing remitting multiple sclerosis patients.

MRI
cladribine
relapsing multiple sclerosis
  • 0 views
  • 01 May, 2021
  • 1 location
None
Defecation Function and Quality of Life in the Patients Treated With Surgery for Slow Transit Constipation

Although surgical options for slow transit constipation (STC) have been proven to be a definite treatment, improvements in the associated defecation function and quality of life are rarely studied. This study aims to investigate the effectiveness of total or subtotal colectomy, with respect to short- and long-term defecation function and …

  • 2 views
  • 24 Jan, 2021
  • 1 location