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Found 157 clinical trials
Prospective Case-control Study in Patients With PAA

The overall objective is to highlight different aspects of care in patients with PAA before and after treatment, and identifying factors that influence the outcome of PAA patients.

intermittent claudication
  • 52 views
  • 20 Feb, 2022
  • 2 locations
The CURE - CD Trial

A prospective randomized three-arms controlled trial of Crohn's Disease (CD) patients in remission of <24 months duration. Patients will undergo screening by Magnetic Resonance Enterography (MRE) and patency capsule, and (if agreeing by separate consent) a baseline colonoscopy. Patients in whom patency of small bowel is proven will undergo video-capsule …

endoscopy
capsule endoscopy
enteropathy
remission
  • 7 views
  • 05 Mar, 2022
  • 1 location
Personalized Multi-peptide Vaccination in CLL Patients

The aim of this study is to evaluate the efficiency along with safety and toxicity of a personalizied multi-peptide vaccine in combination with the TLR1/2 ligand XS15 in CLL patients undergoing ibrutinib-based regimes.

lymphadenopathy
constitutional symptoms
remission
flow cytometry
corticosteroids
  • 0 views
  • 18 Sep, 2021
  • 1 location
IKKb-matured RNA-loaded Dendritic Cells for Metastasised Uveal Melanoma

A Phase I vaccination trial in patients suffering from recently diagnosed metastatic uveal melanoma not cureable with local therapy and needing systemic therapy. IKKb-matured Dendritic Cells loaded with autologous tumor-RNA + RNA coding for defined antigens and driver mutations will be added to a standard therapy chosen by the tumor …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Vaginal Native Tissues Repair for Pelvic Organ Prolapse (TAPP)

The aim of the study is to assess at one year the effectiveness of the vaginal patch plastron in comparison of the anterior colporraphy through a combined definition of success: anatomic and functional.

  • 0 views
  • 19 Feb, 2022
  • 9 locations
CMP-001 and Pre-operative Stereotactic Body Radiation Therapy (SBRT) in Early Stage Triple Negative Breast Cancer (TNBC)

This is an open-label, randomized, window-of-opportunity phase 2 clinical study evaluating the biological activity of preoperative Stereotactic Body RadioTherapy (SBRT) alone (Arm 1), and combined with subcutaneous (SC) followed by intra-tumoral (IT) administrations of CMP-001 (Arm 2), in subjects with early stage TNBC. Safety and efficacy of the treatments are …

immunohistochemistry
epidermal growth factor receptor
mammogram
erbb2
measurable disease
  • 0 views
  • 19 Jul, 2021
  • 1 location
A Pilot Study in Severe Patients With Takayasu Arteritis.

Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. We classify TAK patients into 3 levels, including mild, moderate, and severe. And the biological agents tocilizumab and adalimumab are randomly prescribed in severe patients, to find out the relatively better treatment strategy, facilitating …

tocilizumab
adalimumab
  • 0 views
  • 01 Mar, 2022
  • 1 location
Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients

Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. Here we tried to classify TAK patients in 3 levels, including mild, moderate, and severe, and prescribe methotrexate and tofacitinib randomly in mild and moderate patients, to observe the relatively better treatment strategy, facilitating …

methotrexate
tofacitinib
  • 4 views
  • 01 Mar, 2022
  • 1 location
Improvement of Diagnostic Approach Using PoCUS for Right Upper Quadrant Abdominal Pain (DARUQUS)

Many medical specialties and paramedical fields are increasingly using point-of-care ultrasound (PoCUS). In daily practice, abdominal pain accounts for 7% to 10% of emergency department consultations, while the mean reported prevalence of abdominal pain in family physician consultations is 2.8%. PoCUS can be used in a variety of ways during …

  • 0 views
  • 07 Oct, 2022
  • 1 location
Heterogeneously Hypofractionated Radiotherapy for Locally Advanced NSCLC

The options for patients with locally advanced non-small cell lung cancer (NSCLC) who are not candidates for a standard definitive chemoradiotherapy regime are meagre. These are patients who are not fit for a chemoradiotherapy schedule of 66 Gy in 2 Gy fractions due to either tumour extent, resulting in excessive …

  • 0 views
  • 04 Oct, 2022
  • 1 location