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Found 128 clinical trials
Featured trial
Heart Valve Disease – Aortic and Mitral

Study Description: Multi-center, international, prospective, randomized, interventional, pre-market study. Patients will be seen at pre and post-procedure, discharge, 30 days, 6 months, 1 year, 18 months, and annually through 10 years. Randomly assigned (50% to either group) Treatment of Aortic Stenosis with either Transcatheter Aortic Valve Replacement (TAVR) device or …

aortic valve replacement
stenosis
  • 776 views
  • 05 Feb, 2021
  • 1 location
None
Comparing Hypothermic Temperatures During Hemiarch Surgery

Hypothermic circulatory arrest is an important surgical technique, allowing complex aortic surgeries to be performed safely. Hypothermic circulatory arrest provides protection to cerebral and visceral organs, but may result in longer cardiopulmonary bypass times during surgery, increased risks of bleeding, inflammation, and neuronal injury. To manage these consequences, a trend …

  • 0 views
  • 22 Sep, 2021
  • 5 locations
None
Personalized Activity Intervention in Rehabilitation After Cardiac Operations (the PACO Trial)

The PACO trial is a randomized clinical trial conducted in Heart Centers of Kuopio and Turku university hospitals. The coronary artery disease, aortic valve stenosis and mitral valve

stenosis
coronary artery disease
mitral valve repair
regurgitation
bypass graft
  • 53 views
  • 23 Jan, 2021
  • 1 location
None
Endovascular Repair of Descending ThoracoAbdominal Aortic Pathologies Using Physician Modified Endovascular Prosthesis

This is an early feasibility study that investigates the outcome of selected patients with complex thoracoabdominal aortic lesions who are suitable for endovascular (within the vessel) repair with a physician-modified Medtronic Thoracic Valiant stent graft. The Medtronic Valiant System includes a Valiant Thoracic Stent Graft, a self-expanding, tubular end prosthesis …

tubular
aneurysm
  • 0 views
  • 26 Jan, 2021
  • 2 locations
None
Ultrasound-Guided Resuscitation in Open Aortic Surgery

This study will aim to determine whether routine Point of Care Ultrasound (POCUS) assessment of volume status, cardiac function, and pulmonary function after major abdominal aortic surgery is an accurate and feasible form of monitoring for individualized, goal-directed resuscitation. Half of the patients will receive POCUS-guided fluid resuscitation, and the …

aortic aneurysm
endarterectomy
elective surgical procedures
aortic surgery
aneurysm
  • 0 views
  • 08 Mar, 2021
  • 1 location
None
Effects of MICT on Cardiopulmonary Function in Patients After TAVI

Cardiac rehabilitation (CR), particularly regular exercise, can improve the cardiopulmonary function, exercise capacity, and quality of life for patients undergoing transcatheter aortic valve implantation (TAVI). Consequently, the patients after TAVI will be enrolled in our randomized controlled trial to demonstrate if the moderate-intensity continuous training (MICT) can improve the cardiopulmonary …

  • 0 views
  • 07 Nov, 2021
  • 1 location
None
Increased Saline Flush to Reduce the Amount of Residual Air Inside a Stentgraft Delivery System

Non-randomized studies have shown that de-airing of the delivery system with an increased volume of saline may be associated to a decrease in periprocedural stroke during thoracic endovascular aortic repair. This study is designed to provide evidence that 4xIFU-dose volume of saline flush vs. standard IFU-dose saline flush is associated …

aortic aneurysm
stroke
aneurysm
  • 0 views
  • 17 Jun, 2021
  • 1 location
None
Effects of Ischemic Preconditioning After Aortic Clamping

Open surgery for aneurysmal aortic disease can lead to cardiac, renal, pulmonary or muscular complications, essentially due to the aortic clamping. Ischemic preconditioning can be useful in

  • 0 views
  • 14 Oct, 2021
  • 4 locations
None
Feasibility of Endovascular Repair Of Ascending Aortic Pathologies

The purpose of this study is to investigate the outcome of patients with pathologies of the ascending thoracic aorta (diseases in the great blood vessel or artery that leads away from the heart

aneurysm
hematoma
dissections
type b aortic dissection
clot
  • 13 views
  • 14 Apr, 2021
  • 3 locations
None
Effect of PCSK9 InhibitorS On Calcific Aortic Valve DiseasE

Calcific Aortic Stenosis (CAS) can cause severe adverse cardiac events, but there is currently no effective drug that can prevent or delay the progression of the disease, aortic valve

aortic valve stenosis
stenosis
  • 0 views
  • 17 Sep, 2021
  • 1 location