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Found 74 clinical trials
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing (INSTAR)

The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection, stratified by rhinovirus genome load. The secondary objectives are to determine duration and severity of each acute episode with acute expiratory breathing …

wheezing
corticosteroid therapy
corticosteroids
steroid therapy
  • 34 views
  • 29 May, 2022
  • 10 locations
Self-testing for HCV Re-infection in MSM (SELFIE)

HIV+MSM (men who have sex with men) that have been cured of a hepatitis C viral infection (HCV) are at risk for HCV re-infection (5-10% per year). One intervention to reduce HCV incidence in this population may be to decrease the time to diagnosis of HCV re-infections in order to …

  • 17 views
  • 15 Feb, 2022
  • 1 location
An Open Label Study in Adults to Test the Efficacy of Mitoquinone/Mitoquinol Mesylate to Prevent Severe Viral Illness

Open label clinical trial of healthy persons (adults) who will receive the diet supplement oral mitoquinone/mitoquinol mesylate (Mito-MES) to prevent the development and progression of severe viral infections like COVID-19 after high-risk exposure to a person with possible respiratory viral infection such as SARS-CoV-2 infection.

Accepts healthy volunteers
  • 0 views
  • 12 Jul, 2022
  • 1 location
Effect of Direct-acting Antiviral Drugs on Erectile Function

Effect of direct-acting antiviral drugs on erectile function

chronic hepatitis
sofosbuvir
daclatasvir
  • 38 views
  • 26 Feb, 2022
  • 1 location
ANTIVIRAL TREATMENT OF CYTOMEGALOVIRUS IN DEPRESSION

This study aims to determine whether treatment of CMV positive (CMV+) individuals with major depressive disorder (MDD) with valganciclovir (VGCV) alters neural circuitry, reduces inflammation, and improves depressive behavior and symptoms to a greater extent than placebo. In this double-blind, randomized placebo-controlled, parallel group trial, 24 individuals with a Quick …

  • 0 views
  • 26 Mar, 2022
  • 1 location
Antiviral Therapy for Patients With Chronic Hepatitis B Infection

The study aims to demonstrate that antiviral therapy for patients with immune tolerance of CHB. On the basis of the original antiviral therapy of entecavir, further clarify the safety and effectiveness of entecavir combined with tenofovir amibufenamide.The investigators plan to enroll about 328 hepatitis B patients,. who are in the …

entecavir
tenofovir
antiviral therapy
hepatitis
  • 0 views
  • 08 Jun, 2022
  • 1 location
LinkPositively: A Technology-Delivered Peer Navigation and Social Networking Intervention to Improve HIV Care

Investigators will develop and pilot test a culturally tailored, trauma-informed smartphone app, called LinkPositively, for Black WLHA affected by interpersonal violence. Core components of LinkPositively include: a) Virtual Peer Navigation that includes phone and text check-ins and 4 weekly one-on-one video sessions to build skills to cope with barriers and …

  • 0 views
  • 29 Oct, 2021
  • 1 location
Clinical Study of Antiviral and Aspirin Treatment in Liver Cancer After Radical Surgery

Evaluation the Treatment Outcome of Antiviral and Aspirin Treatment in Liver Cancer After Radical Surgery.

cancer
antiviral drugs
liver cancer
lamivudine
  • 0 views
  • 14 Feb, 2022
Study for Evaluation of the Safety, Pharmacokinetics, and Antiviral Activity of UB-421 Subcutaneous Formulation Administered in HIV-1 Infected Treatment Naive Patients

This is a phase I, open-label, dose-escalation study to investigate short-term safety, pharmacokinetics, and antiviral activity of UB-421 SC with 4 weekly doses in treatment naive HIV-1 infected patients. Eligible (n=6 per dose cohort) subjects will be sequentially enrolled into 3 escalating-dose cohorts to receive 4 weekly fixed doses of …

  • 0 views
  • 27 May, 2022
  • 1 location
A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-H3733 in Subjects With Chronic Hepatitis B Virus Infection

This is a randomized, blinded, placebo-controlled, dose-ranging Phase 1b study of the safety, PK, and antiviral activity of ABI-H3733 in treatment-naïve or off-treatment chronic Hepatitis B virus (cHBV) subjects that are Hepatitis B e antigen (HBeAg) positive or negative. The study will enroll up to 5 sequential cohorts of 10 …

cirrhosis
body mass index
antiviral therapy
hepatitis
  • 0 views
  • 03 Jul, 2022
  • 2 locations