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Found 57 clinical trials
Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation

This study is a randomized, prospective, comparative study of the effectiveness of prophylactic entecavir treatment for HBV reactivation in past HBV infected patients (HBsAg-, HBcIgG+) with hematopoietic stem cell transplantation.

entecavir
hepatitis b core antibody
  • 0 views
  • 26 Jul, 2021
  • 1 location
Transplantation Using Hepatitis C Positive Donors, A Safety Trial

. Prior to transplantation, recipients will receive an initial dose of highly effective antiviral prophylaxis using approved direct-acting antivirals (DAAs) Glecaprevir/Pibrentasvir (G/P) and they will

glecaprevir
pibrentasvir
antiviral drugs
  • 10 views
  • 12 Feb, 2022
  • 1 location
Natural Killer Cell (CYNK-001) Infusions in Adults With AML (CYNK001AML01)

This study will find the maximum tolerated dose or the maximum planned dose of CYNK-001 which contains natural killer (NK) cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given after lymphodepleting chemotherapy. The safety of this treatment will be evaluated, and researchers want to learn …

remission
cell transplantation
flow cytometry
immunosuppressant
refractory acute myeloid leukemia (aml)
  • 43 views
  • 27 Jun, 2022
  • 7 locations
Clinical Trial of Efficacy and Safety of the Combination of Reduced Duration Prophylaxis Followed by Immuno-guided Prophylaxis in Lung Transplant Recipients. (CYTOCOR)

To assess the efficacy of reduced duration prophylaxis followed by immuno-guided prophylaxis to prevent cytomegalovirus disease.

valganciclovir
dhpg
ganciclovir
  • 1 views
  • 17 Feb, 2022
  • 6 locations
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing (INSTAR)

The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection, stratified by rhinovirus genome load. The secondary objectives are to determine duration and severity of each acute episode with acute expiratory breathing …

wheezing
corticosteroids
steroid therapy
corticosteroid therapy
  • 34 views
  • 29 May, 2022
  • 10 locations
Self-testing for HCV Re-infection in MSM (SELFIE)

HIV+MSM (men who have sex with men) that have been cured of a hepatitis C viral infection (HCV) are at risk for HCV re-infection (5-10% per year). One intervention to reduce HCV incidence in this population may be to decrease the time to diagnosis of HCV re-infections in order to …

  • 17 views
  • 15 Feb, 2022
  • 1 location
An Open Label Study in Adults to Test the Efficacy of Mitoquinone/Mitoquinol Mesylate to Prevent Severe Viral Illness

Open label clinical trial of healthy persons (adults) who will receive the diet supplement oral mitoquinone/mitoquinol mesylate (Mito-MES) to prevent the development and progression of severe viral infections like COVID-19 after high-risk exposure to a person with possible respiratory viral infection such as SARS-CoV-2 infection.

Accepts healthy volunteers
  • 0 views
  • 12 Jul, 2022
  • 1 location
Effect of Direct-acting Antiviral Drugs on Erectile Function

Effect of direct-acting antiviral drugs on erectile function

daclatasvir
chronic hepatitis
sofosbuvir
  • 38 views
  • 26 Feb, 2022
  • 1 location
Clinical Study of Antiviral and Aspirin Treatment in Liver Cancer After Radical Surgery

Evaluation the Treatment Outcome of Antiviral and Aspirin Treatment in Liver Cancer After Radical Surgery.

lamivudine
cancer
antiviral drugs
liver cancer
  • 0 views
  • 14 Feb, 2022
Study for Evaluation of the Safety, Pharmacokinetics, and Antiviral Activity of UB-421 Subcutaneous Formulation Administered in HIV-1 Infected Treatment Naive Patients

This is a phase I, open-label, dose-escalation study to investigate short-term safety, pharmacokinetics, and antiviral activity of UB-421 SC with 4 weekly doses in treatment naive HIV-1 infected patients. Eligible (n=6 per dose cohort) subjects will be sequentially enrolled into 3 escalating-dose cohorts to receive 4 weekly fixed doses of …

  • 0 views
  • 27 May, 2022
  • 1 location