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Found 50 clinical trials
HCV Reinfection in in HIV/HCV-coinfected Patients Achieving SVR by Antiviral Therapy

Chronic hepatitis C virus (HCV) infection remains a health burden in people living with human immunodeficiency virus (HIV). Interferon (IFN)-based therapy is the treatment of choice for HCV infection for HIV coinfected patients in earlier years. However, the treatment responses are far from ideal and the treatment-emergent adverse events (AEs) …

  • 0 views
  • 05 Mar, 2021
  • 7 locations
HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS Function

The primary objective of this research project is to compare neuropsychiatric functioning, cortical activity, white matter integrity, and immune response among Veterans with and without alcohol use disorder (AUD), before and after direct-acting antiviral (DAA) therapy [a new treatment for chronic infection with the hepatitis C virus (HCV)]. Demographically-matched comparison …

antiviral therapy
drugs of abuse
chronic infection
antiviral drugs
alcohol abuse
  • 4 views
  • 04 Oct, 2022
  • 1 location
Stopping Antiviral Treatment in Chronic Hepatitis B

complications. Many patients require long-term oral antiviral therapy since off-treatment sustained virological control can only be achieved in a minority of patients. It is uncommon for patients taking long

cirrhosis
antiviral therapy
entecavir
hepatitis
tenofovir
  • 0 views
  • 16 Oct, 2021
  • 1 location
Clinical Characteristics, Natural Outcome and Treatment Optimization of Refractory

viremia. Currently, there is no consensus on salvage therapy for patients who remain virus-positive after a second round of antiviral therapy. This is the first multicenter, prospective, parallel

antiviral drugs
  • 0 views
  • 29 May, 2022
  • 13 locations
Treatment and Prognosis of Patients With Chronic HBV Infection

efficacy of antiviral therapy and the prognosis of patients with differential therapeutic strategies.

antiviral therapy
hepatitis
Accepts healthy volunteers
  • 0 views
  • 06 Jun, 2022
  • 1 location
Prediction of BKvirus Nephropathy Risk by the NEPHROVIR Method in Kidney Transplant Patients With BKvirus Viremia (BK-VIR)

in more than 50% of cases. Without current antiviral therapy, the treatment consists of minimizing immunosuppression, secondarily exposing the patient to a graft rejection risk. Impaired BKv specific

immunosuppression
renal impairment
immunosuppressants
kidney transplant
  • 0 views
  • 27 May, 2022
  • 1 location
LDT Combined With TDF to Improve EGFR Decreasing in Patients With Chronic Hepatitis B Treated With TDF

Chronic hepatitis B (CHB) is an important public health problem in the world. There are still more than 250 million chronic hepatitis B virus (CHB) infected people in the world. Its preventive effect has reached a relatively ideal effect, but its therapeutic effect still has great room for improvement. Tenofovir(TDF) …

  • 0 views
  • 27 Jan, 2021
  • 1 location
HCV Reinfection in HD Patients Achieving SVR

Among the hemodialysis units, the global incidence of HCV infection ranges from 1.2% to 2.9%. Data regarding the long-term risk of reinfection among hemodialysis patients achieving SVR are limited. To our best knowledge, only one study assessed the long-term negativity of serum HCV RNA in hemodialysis patients who achieved SVR …

  • 0 views
  • 06 Mar, 2021
  • 7 locations
Antiretroviral Pregnancy Registry (APR)-Risk of Birth Defects

The APR began as the 'Zidovudine in pregnancy Registry' in January 1989 and became the 'Antiretroviral Pregnancy Registry' in January, 1993. The purpose of the APR is to detect any major teratogenic effects involving any of the Registry drugs when administered to pregnant HIV positive women. The Registry is intended …

antiretroviral agents
lamivudine/zidovudine
zidovudine
abacavir
antiretroviral therapy
  • 26 views
  • 30 Jan, 2022
  • 1 location
Kidney in Coronavirus Disease 2019 Registry (KidneyCOVID19)

The SARS-CoV-2 virus is a virus newly identified in January 2020. The WHO defined COVID-19 as a health emergency of international importance. The clinical manifestation of the COVID-19 disease cannot be fully described in the short time. First insights in patients suffering from acute kidney injury (AKI) during COVID-19 indicate …

  • 0 views
  • 02 Jun, 2022
  • 1 location