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Found 51 clinical trials
Safety and Immunity of Covid-19 aAPC Vaccine

In December 2019, viral pneumonia (Covid-19) caused by a novel beta-coronavirus (SARS-CoV-2) broke out in Wuhan, China. Some patients rapidly progressed and suffered severe acute respiratory failure and died, making it imperative to develop a safe and effective vaccine to treat and prevent severe Covid-19 pneumonia. Based on detailed analysis …

  • 181 views
  • 01 Mar, 2022
  • 1 location
A Dose-Escalation Study Evaluating Safety and Tolerability of Viral-Specific T Cells Against CMV in Adult Solid Organ Transplant Recipients

This study measures the tolerability of viral-specific T cells against Cytomegalovirus (CMV) in adult solid organ transplant (SOT) recipients. Participants are expected to be on study for 52 +/- 3 weeks.

hla-a
dhpg
pneumonia
viral therapy
colitis
  • 2 views
  • 15 Feb, 2022
  • 1 location
Immunity and Safety of Covid-19 Synthetic Minigene Vaccine

In December 2019, viral pneumonia caused by a novel beta-coronavirus (Covid-19) broke out in Wuhan, China. Some patients rapidly progressed and suffered severe acute respiratory failure and died, making it imperative to develop a safe and effective vaccine to treat and prevent severe Covid-19 pneumonia. Based on detailed analysis of …

  • 821 views
  • 27 Feb, 2022
  • 3 locations
Impact of Weight Loss in Cirrhosis With Obesity and MAFLD

Nutrition therapy is the cornerstone of medical therapy in patients with cirrhosis. 70% compensated patients with Chronic Liver Disease (CLD) are overweight or obese. Obesity in CLD augments decompensation, plausibly through increase in portal pressure. Moreover, the cardiometabolic risk factors are increased with increase in body weight, obesity also has …

fats
fibroscan
liver disease
  • 0 views
  • 19 Nov, 2021
  • 1 location
Novel Method of Pancreatic Islet Transplantation Into the Omentum

The investigators propose to conduct a pilot clinical study in 10 type 1 diabetic subjects suffering from hypoglycemia unawareness syndrome and episodes of severe hypoglycemia, in which therapy with transplantation of allogeneic pancreatic islets would be indicated according to current criteria at the Institute for Clinical and Experimental Medicine (IKEM). …

  • 0 views
  • 05 Sep, 2021
  • 1 location
Reduced Intensity BMT for Immune Dysregulatory and Bone Marrow Failure Syndromes Using Post-Transplant Cyclophosphamide

This is a Phase II prospective trial to assess the rates of donor engraftment using reduced intensity conditioning (RIC) hematopoietic stem cell transplant (HSCT) and post-transplant cyclophosphamide (PTCy) for patients with primary immune deficiencies (PID), immune dysregulatory syndromes (IDS), and inherited bone marrow failure syndromes (IBMFS).

hla-a
immunoglobulin e
wiskott-aldrich syndrome
alemtuzumab
stem cell transplantation
  • 3 views
  • 24 Feb, 2022
  • 1 location
Post Coronavirus Disease (COVID-19) Syndrome Indonesian Population

medications (including early administration of antiviral therapy) lead to a lower probability of persistent COVID 19 Symptoms

  • 0 views
  • 20 Jul, 2022
  • 2 locations
Surveillance for Antiviral Resistant Variants in Chronic Hepatitis C Patients (SEARCH-C)

This is a multi-centre prospective longitudinal cohort study with the aim of collecting and storing clinical data, patient blood, DNA and PBMCs to examine outcomes related to drug resistance, drug monitoring and host genetics in the era of directly acting antiviral drugs for hepatitis C therapy.

  • 31 views
  • 21 Apr, 2022
  • 2 locations
Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral Products

Background Vaccines and antiviral therapies help prevent and treat diseases. Researchers need a group of healthy volunteers for clinical trials. Clinical trials are studies that test these vaccines and therapies in people. Objective To screen volunteers for clinical trials for investigational or licensed vaccines or drugs to treat or prevent …

Accepts healthy volunteers
antiviral
  • 133 views
  • 18 Sep, 2022
  • 1 location
Relationships Among Inflammation Physical and Mental Health in Subjects With Chronic Inflammatory Physical Diseases.

The prevalence of common mental disorders is high in patients with chronic inflammatory physical diseases(e.g., autoimmune or infectious diseases). The traditional explanatory causation model in which physical symptoms and related disability drive mental health problems is now called into question, and evidence has accumulated supporting more complex interactions whereby psychiatric …

anxiety
HIV Infection
dermatitis
HIV Vaccine
psoriasis
  • 0 views
  • 26 Nov, 2021
  • 1 location