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Found 51 clinical trials
Allogeneic Adoptive Immune Therapy for Advanced AIDS Patients

Combined antiretroviral therapy (ART) efficiently suppresses viral replication and markedly decreases mortality among patients with HIV-1 infection/AIDS. While the advanced AIDS patients with CD4+T cell count less than 200 cells/L often develop seriously opportunistic infections (OIs), severe wasting syndrome, and other fatal complications, which are the major causes of death …

  • 0 views
  • 16 Feb, 2022
  • 1 location
Serum Alpha-fetoprotein Levels and Response to Direct Antiviral Therapy in Patients With Chronic Hepatitis C

Alpha-fetoprotein Levels on the Response to direct Antiviral Therapy in Patients with Chronic Hepatitis C

chronic hepatitis
alpha fetoprotein
antiviral therapy
ledipasvir/sofosbuvir
sofosbuvir
  • 10 views
  • 24 Feb, 2022
  • 1 location
Neovac 2 Burkina Faso: Impact of the Integration of Hepatitis B Birth Dose Vaccine Into the Infant Immunization Schedule (NEOVAC2BK)

national program and to imply whether additional strategy (e.g., maternal screening and antiviral therapy during pregnancy) might be necessary in order to eliminate the risk of mother-to-child transmission

antiviral therapy
vaccination
immunization schedule
hepatitis
Accepts healthy volunteers
  • 0 views
  • 30 Apr, 2022
  • 2 locations
ETHOS ENGAGE: Enhancing Treatment of Hepatitis C in Opioid Substitution Settings (ETHOS II)

The overall goals of the ETHOS II Project are to enhance hepatitis C virus (HCV) care in drug treatment clinics and needle and syringe programs (NSPs) in New South Wales and Australia, and to develop a translational framework for subsequent establishment of HCV screening and treatment programs in drug treatment …

Accepts healthy volunteers
drug use
  • 56 views
  • 21 Apr, 2022
  • 6 locations
Pre-operative Carriage of Respiratory VIRUSes, and Acute Respiratory Distress Syndrome After Heart Surgery (VIRUS-ATTAC)

The main objective of our study is to determine whether asymptomatic influenza virus carriage is associated with an increased risk of post-operative Acute Respiratory Distress Syndrome (ARDS) after cardiac surgery. Cardiac surgery patients are particularly at risk of developing ARDS with an estimated incidence of 5-10% based on the most …

  • 0 views
  • 10 May, 2022
  • 4 locations
Antiviral Therapy for Patients With Chronic Hepatitis B Infection

The study aims to demonstrate that antiviral therapy for patients with immune tolerance of CHB. On the basis of the original antiviral therapy of entecavir, further clarify the safety and

tenofovir
entecavir
antiviral therapy
hepatitis
  • 0 views
  • 08 Jun, 2022
  • 1 location
Interferon Lambda for Immediate Antiviral Therapy at Diagnosis in COVID-19 (ILIAD)

Interferon lambda is one of the main arms of the innate antiviral immune response and is critical for controlling respiratory viral infections in mice. Interferon lambda has a better side effect profile than other interferons because of the limited tissue distribution of its receptor. Peginterferon lambda is a long-acting form …

interferon
fever
covid-19
sore throat
antiviral drugs
  • 176 views
  • 22 Mar, 2022
  • 5 locations
Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors

This phase III trial studies the effect of tenofovir alafenamide in preventing liver complications in patients with current or past hepatitis B virus (HBV) who are receiving anti-cancer therapy for solid tumors. People with chronic or past HBV who are undergoing therapy for cancer are at an increased risk for …

hepatitis b core antibody
cancer
cirrhosis
adefovir
liver cancer
  • 17 views
  • 26 Apr, 2022
  • 114 locations
Adjuvant Entecavir or Tenofovir for Postoperative HBV-HCC

This study aims to compare the effect of antiviral therapy with entecavir or tenofovir for hepatitis B virus-related hepatocellular carcinoma after radical hepatectomy. Included patients will

hepatitis b surface antigen
Accepts healthy volunteers
antiviral drugs
hepatectomy
entecavir
  • 4 views
  • 24 Mar, 2022
  • 1 location
Therapy for Hepatitis C Virus (HCV) in Primary Treatment Failure in Pakistan

identify a cohort of patients who have not responded to first-line antiviral therapy (sofosbuvir plus daclatasvir) and the optimal treatment for these patients is unclear. This trial will address this

  • 0 views
  • 14 Mar, 2022
  • 1 location