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Found 318 clinical trials
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Safety and Immunotherapeutic Activity of Cemiplimab in Participants With HBV on Suppressive Antiviral Therapy

The purpose of this study is to evaluate the safety and immunotherapeutic activity of cemiplimab in participants with hepatitis B virus (HBV) on suppressive antiviral therapy.

  • 1 views
  • 03 Oct, 2021
  • 8 locations
None
Evaluate the Safety Tolerability and Antiviral Activity of GLS4 With Ritonavir in Patients With Chronic HBV Infection

The experiment is divided into two parts: Part 1 and Part 2.Part 1 was the initial treatment patient and Part 2 was the treated patient.

  • 4 views
  • 24 Jan, 2021
  • 37 locations
None
Evaluation HEC121120 Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B Pharmacokinetics Characteristics and Antiviral Activity of Phase of Study

The Safety, Tolerability, Pharmacokinetics and antiviral activity Study of Anti hepatitis B virus treatment drug HEC121120 in Healthy subjects and in patients with chronic hepatitis B

Accepts healthy volunteers
  • 0 views
  • 06 Oct, 2021
  • 1 location
None
To Evaluate the Efficacy and Safety of TG-1000 Compared With Placebo in Adult Patients With Acute Uncomplicated Influenza Virus Infection

To evaluate the antiviral effect of TG-1000 compared with placebo in adult patients with acute uncomplicated influenza virus infection.

  • 0 views
  • 01 Oct, 2021
  • 1 location
None
Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides

Both tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) are potent antiviral agents for hepatitis B virus (HBV) and recommended by the American Association for the Study of

chronic hepatitis
tenofovir
adefovir
telbivudine
liver disease
  • 0 views
  • 26 Jan, 2021
  • 10 locations
None
A Study of JNJ-64281802 Against Dengue Serotype 1 Infection in a Dengue Human Challenge Model in Healthy Adult Participants

The purpose of this study is to assess the antiviral activity of JNJ-64281802 versus placebo in terms of reduction of dengue virus 1 (DENV-1) ribonucleic acid (RNA) viral load (VL).

  • 46 views
  • 16 Jun, 2021
  • 1 location
None
HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)

A study to evaluate the antiviral effects, immunogenicity, and safety of HepTcell in treatment-naive patients with inactive Chronic Hepatitis B (CHB) and low Hepatitis B surface antigen (HBsAg

  • 0 views
  • 27 Jan, 2021
  • 1 location
None
Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B:

The objective of this study is to identify immunological mechanisms that contribute to normalization of liver inflammation in chronic hepatitis B (CHB) patients starting the antiviral nucleoside

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
PI Vs. NNRTI Based Therapy for HIV Advanced Disease

Ritonavir boosted protease inhibitor based therapy will have equivalent antiviral efficacy over 48 weeks compared to NNRTI based therapy in patients who are antiretroviral therapy naïve

efavirenz
zidovudine
antiretroviral agents
antiretroviral therapy
lamivudine
  • 42 views
  • 07 Nov, 2020
  • 5 locations
None
Switching Regimen in Treating Cirrhotic HCV GT1b Subjects

This is a prospective, randomized study to evaluate the efficacy and safety of switching treatment from Peg-interferon and Ribavirin to direct-acting antiviral agents in Chinese with CHC

  • 15 views
  • 09 Sep, 2021
  • 2 locations