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Found 327 clinical trials
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Viral Infections in Healthy and Immunocompromised Hosts

Background Viral infections are an important cause of illness and death in hospitalized patients as well as outpatients. New strains of viruses may appear and infect both healthy people and those with weak immune systems. A better understanding of these new virus strains (such as SARS-CoV-2, the virus that causes …

Accepts healthy volunteers
immunoglobulin
  • 258 views
  • 21 Oct, 2021
  • 1 location
None
Treatment as Prevention for Hepatitis C in Iceland

The main aim of this study is to test in the Icelandic population the hypothesis that a nationwide treatment program which offers effective treatment to all known cases of Hepatitis C with the aim of halting HCV (Hepatitis C virus) transmission will lead to a reduction in incidence and disease …

  • 4 views
  • 26 Jan, 2021
  • 1 location
None
Lung Function Exercise Capacity and Serology Responses in Patients With COVID-19

(a) Objectives To assess the full lung function, exercise capacity, quality of life in patients with COVID-19 over 2 years. To assess the longevity of the serology response to SARS-CoV2. To investigate the association of the neutralization titer in plasma from different vaccinated cohorts to its protection of infection using …

  • 0 views
  • 02 Sep, 2021
  • 1 location
None
Prospective Survey of CMV Herpesviruses Infections and Diseases in Allo-HSCT

Prospective observational study of epidemiological surveillance, multicenter, non-profit, spontaneous, Italian with objective to describe the incidence of CMV infections and diseases in adult and pediatric patients undergoing allo-HSCT during the first 6 months from transplant. This study will evaluate approximately 1500 subjects (with competitive enrolment) from GITMO investigational centers.

  • 0 views
  • 25 Aug, 2021
  • 50 locations
None
Influenza in People With Normal and Weakened Immune Systems

This study will evaluate how the immune system responds to influenza infection and compare how the infection differs in patients with a weakened immune system versus those with a healthy immune system. Patients at the NIH Clinical Center who are older than 2 years of age and who are diagnosed …

Accepts healthy volunteers
influenza
  • 74 views
  • 25 Oct, 2021
  • 2 locations
None
Therapeutic Option for Hepatitis B and C: a French Cohort

The cohort will integrate clinical, genetic, pharmacogenomics, environmental, biomarkers and behavioral data in a large number of patients and will be a leading equipment for crossdisciplinary and translational research on hepatitis. The cohort will be the main support for estimating the relative effects of treatments and for further cost-effectiveness studies …

acute hepatitis
hepatitis b
hepatitis b surface antigen
chronic hepatitis
hepatitis c antibody
  • 19 views
  • 21 Jan, 2021
  • 1 location
None
Prediction of Liver-related Outcomes After HCV Cure

Objectives: To develop and validate a predictive model, applicable to daily practice, of liver complications emergence in hepatitis C virus (HCV)-infected patients and advanced fibrosis, who have achieved sustained viral response (SVR) with direct-acting antivirals (DAA)-based therapy. Methods Design: Mulsite prospective multicenter cohort study. Study subjects: HCV-monoinfected and HIV/HCV-coinfected individuals …

shear wave elastography
antiviral drugs
liver transplant
hepatitis
hepatocellular carcinoma
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Respiratory Virus Hospitalization Study (FLU 003 Plus)

Following the sudden and unexpected emergence of influenza A(H1N1)pdm09 (2009 H1N1) virus, this observational study was initiated to estimate rates of morbidity and mortality and to examine predictors of severity among participants with 2009 H1N1 infection. In 2011, as surveillance indicated that 2009 H1N1 virus was co-circulating with other seasonal …

novel influenza a
respiratory tract infection
  • 3440 views
  • 26 Apr, 2021
  • 64 locations
None
Psychological Impact of the Corona Virus (SARS-CoV-2) and COVID-19 Pandemic in Individuals With Psychiatric Disorders

The aim of this study is to measure current affective symptoms and psychological distress in individuals with severe mental illness during the COVID-19 pandemic using an online questionnaire survey. In addition, this study aims at identifying individual beliefs, sleep quality, attitudes concerning the virus, the adherence to the measures, believing …

SARS
covid-19
psychiatric disorder
  • 0 views
  • 04 Aug, 2021
  • 1 location
None
Hepatocellular Carcinoma in HIV-infected Individuals in Asian Population

This is a retrospective study, all HIV-infected individuals followed up at the three designated HIV clinics in Hong Kong with and without HBV and/or HCV co-infection will be included in the analysis. The incidence and mortality of HCC among HIV-infected individuals with and without HBV/HCV co-infection in an Asian population …

  • 0 views
  • 03 Feb, 2021
  • 1 location