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Found 18 clinical trials
Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis B

types of antiviral drugs: α-interferons (plain and pegylated ([PEG-IFN]α-2a or α-2b) interferons) and nucleos(t)ide analogues (NUC) including lamivudine (LAM), adefovir dipivoxil (ADV), entecavir (ETV

  • 0 views
  • 07 Apr, 2022
Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)

effective repurposed antiviral drugs; Positive control: we will initially include the REGN-COV2 (monoclonal antibody cocktail); and later: any future small molecule drugs that pass phase

  • 0 views
  • 21 Mar, 2022
  • 4 locations
Effect of Direct-acting Antiviral Drugs on Erectile Function

Effect of direct-acting antiviral drugs on erectile function

chronic hepatitis
sofosbuvir
daclatasvir
  • 38 views
  • 26 Feb, 2022
  • 1 location
Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation

This study is a randomized, prospective, comparative study of the effectiveness of prophylactic entecavir treatment for HBV reactivation in past HBV infected patients (HBsAg-, HBcIgG+) with hematopoietic stem cell transplantation.

hepatitis b core antibody
entecavir
  • 0 views
  • 26 Jul, 2021
  • 1 location
History of the KSHV Inflammatory Cytokine Syndrome (KICS)

samples will be collected as well. People with KICS that requires treatment may get new experimental treatments. These treatments may include antiviral drugs and chemotherapy drugs, depending

lymphoma
doxorubicin
fever
zidovudine
cancer
  • 81 views
  • 13 May, 2022
  • 1 location
CMV Specific T Cell Therapy After Allogeneic Stem Cell Transplantation.

accompanied by an extremely high mortality rate and therefore the development of new treatment approaches is required. Despite the available antiviral drugs, a considerable number of patients are facing an

stem cell transplantation
antiviral treatment
ganciclovir
antiviral drugs
viral therapy
  • 47 views
  • 24 Feb, 2022
  • 8 locations
Natural Killer Cell (CYNK-001) Infusions in Adults With AML (CYNK001AML01)

This study will find the maximum tolerated dose or the maximum planned dose of CYNK-001 which contains natural killer (NK) cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given after lymphodepleting chemotherapy. The safety of this treatment will be evaluated, and researchers want to learn …

immunosuppressive agents
hysterectomy
immunosuppressant
remission
myeloid leukemia
  • 43 views
  • 02 Mar, 2022
  • 7 locations
Study to Evaluate Induction of HBV Virus Neutralizing Antibodies Using VVX001

The Study will evaluate the effects of VVX001, a novel vaccine for hepatitis B, to elicit a robust protective IgG immune response in vaccine naive subjects in subjects who failed to demonstrate seroconversion after treatment with a licensed hepatitis B vaccine and in patients chronically infected with HBV.

vaccination
Accepts healthy volunteers
hepatitis
hepatitis b core antibody
hepatitis b antigen
  • 12 views
  • 12 Feb, 2022
  • 2 locations
Chronic Hepatitis b Patients Switch to tAf After Discontinuation of Nucleoside Analogue

We will conduct a phase 4, multicenter, open-label trial at 7 academic centers in Taiwan. Chronic hepatitis B patients receiving oral antiviral therapy (entecavir [ETV], tenofovir disoproxil fumarate [TDF]) for at least 2 years, and fulfil the following nucleos(t)ide analogs discontinuation criteria. After nucleos(t)ide analogs discontinuation, patients had a clinical …

tenofovir
fumarate
entecavir
hepatitis
antiviral therapy
  • 0 views
  • 12 Aug, 2021
  • 7 locations
Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

This phase II trial studies how well Triplex vaccine works in preventing cytomegalovirus (CMV) infection in patients undergoing a hematopoietic stem cell transplantation. CMV is a virus that may be carried for life and does not cause illness in most healthy individuals. However, in people whose immune systems are lowered …

chronic lymphocytic leukemia
lymphoma
immunosuppressive agents
immunosuppressive
immunosuppressant
  • 13 views
  • 19 Feb, 2022
  • 1 location