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Found 25 clinical trials
Administration of Virus Specific CTLs for the Prophylaxis and Treatment of EBV/CMV Infections After HSCT in China

Cytomegalovirus (CMV) and Epstein Barr Virus (EBV) cause significant morbidity and mortality in hematopoietic stem cell transplantation (HSCT) patients in China. Antiviral drugs given either

stem cell transplantation
antiviral drugs
cmv infection
nephropathy
  • 3 views
  • 08 Nov, 2020
  • 1 location
Convalescent Plasma Compared to the Best Available Therapy for the Treatment of SARS-CoV-2 Pneumonia

evidence. Treatment options currently include broad-spectrum antiviral drugs but the efficacy and safety of these drugs is still unknown. Convalescent plasma has previously been used to treat

covid-19
respiratory infection
SARS
antiviral drugs
pneumonia
  • 0 views
  • 24 May, 2020
  • 1 location
The Optimizing Treatment of Peginterferon (PEG IFN) Alpha in Chronic Hepatitis B Virus Patients With Low Level HBsAg

HBeAg-negative chronic hepatitis B (CHB) patients with low Level HBsAg and with a history of drug resistance or suboptimal/partial virological response were enrolled. After giving informed consent, patients were treated with nucleoside analog(s) (NAs) once a day and weekly subcutaneous injections of alfa-2a 180 micrograms/week or peginterferon alfa-2b 80 micrograms/week …

peginterferon
hepatitis b surface
nucleoside analog
hepatitis b e antigen
chronic hepatitis
  • 1 views
  • 08 Nov, 2020
  • 1 location
HBsAg Loss/Seroconversion in Low Replicative Chronic Hepatitis B Virus(HBV) Infection Patients

HBsAg Loss/Seroconversion is uncommon in Low replicative chronic HBV infection patients. The purpose of this study is to investigate the ability of peginterferon alpha to achieve HBsAg loss/seroconversion therapy in Low replicative chronic HBV infection patients with Low Level HBsAg.

peginterferon
hepatitis b surface
hepatitis b e antigen
chronic hepatitis
antiviral therapy
  • 4 views
  • 08 Nov, 2020
  • 1 location
Study to Evaluate Induction of HBV Virus Neutralizing Antibodies Using VVX001

The Study will evaluate the effects of VVX001, a novel vaccine for hepatitis B, to elicit a robust protective IgG immune response in vaccine naive subjects in subjects who failed to demonstrate seroconversion after treatment with a licensed hepatitis B vaccine and in patients chronically infected with HBV.

hepatitis
vaccination
hepatitis b antigen
hepatitis b core antibody
  • 6 views
  • 08 Nov, 2020
Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus(EBV) related malignancy and is an endemic disease in Southeast Asian countries. EBV had been identified as a therapeutic target in some EBV related cancer such as lymphoma and NPC. In cancer cell, EBV was in latent phase and expressed 8-11 genes for maintaining …

absolute neutrophil count
metastatic nasopharyngeal carcinoma
valproic acid
platelet count
carcinoma
  • 0 views
  • 08 Nov, 2020
  • 1 location
Trial of Treatments for COVID-19 in Hospitalized Adults

This study is a multi-centre, adaptive, randomized, open clinical trial of the safety and efficacy of treatments for COVID-19 in hospitalized adults. The study is a multi-centre/country trial that will be conducted in various sites in Europe with Inserm as sponsor. Adults (18 year-old) hospitalized for COVID-19 with SpO2 94% …

hydroxychloroquine
covid-19
respiratory failure
mechanical ventilation
lopinavir/ritonavir
  • 310 views
  • 31 Dec, 2020
  • 54 locations
Effect of Direct-acting Antiviral Drugs on Erectile Function

Effect of direct-acting antiviral drugs on erectile function

daclatasvir
sofosbuvir
chronic hepatitis
  • 38 views
  • 28 Oct, 2020
  • 1 location
Study to Evaluate the Safety and PK of Elpida in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food Intake and Drug-Drug Interactions With Other Antiviral Drugs

), as well as to assess the impact of food intake and drug-drug interactions in case of Co-administration with other antiviral drugs in healthy subjects.

body mass index
antiviral drugs
drug tests
moderate hepatic insufficiency
  • 2 views
  • 08 Nov, 2020
  • 1 location
History of the KSHV Inflammatory Cytokine Syndrome (KICS)

samples will be collected as well. People with KICS that requires treatment may get new experimental treatments. These treatments may include antiviral drugs and chemotherapy drugs, depending

herpes
fever
doxorubicin
cancer
edema
  • 81 views
  • 02 Nov, 2020
  • 1 location