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Found 21 clinical trials
Effect of Direct-acting Antiviral Drugs on Erectile Function

Effect of direct-acting antiviral drugs on erectile function

sofosbuvir
daclatasvir
chronic hepatitis
  • 38 views
  • 26 Jan, 2021
  • 1 location
Relative Mitochondrial Toxicity of Tenofovir Alafenamide (TAF) vs. Tenofovir Disoproxil Fumarate (TDF)

Increased comorbidities such as cardiovascular disease (CVD), are emerging problems in HIV infection but the mechanisms are unclear. Understanding how antiretrovirals can minimize morbidity in treated HIV infection is a research priority. Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) are included in all HIV treatment regimens. Tenofovir (TFV) disoproxil fumarate (TDF) has …

flexible sigmoidoscopy
renal function
HIV Infection
cardiovascular disease
tenofovir
  • 46 views
  • 09 May, 2021
  • 1 location
Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation

This study is a randomized, prospective, comparative study of the effectiveness of prophylactic entecavir treatment for HBV reactivation in past HBV infected patients (HBsAg-, HBcIgG+) with hematopoietic stem cell transplantation.

entecavir
hepatitis b core antibody
  • 0 views
  • 26 Jul, 2021
  • 1 location
Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS

-19. Additionally further trials and clinical observations have not found a significant benefit of other antiviral drugs. Although the results of several studies are still pending, there is still a

covid-19
coronavirus
acute lung injury
SARS
pneumonia
  • 0 views
  • 29 May, 2021
  • 2 locations
History of the KSHV Inflammatory Cytokine Syndrome (KICS)

samples will be collected as well. People with KICS that requires treatment may get new experimental treatments. These treatments may include antiviral drugs and chemotherapy drugs, depending

imaging procedure
doxorubicin
herpes
lymphoma
zidovudine
  • 81 views
  • 01 Aug, 2021
  • 1 location
CMV Specific T Cell Therapy After Allogeneic Stem Cell Transplantation.

accompanied by an extremely high mortality rate and therefore the development of new treatment approaches is required. Despite the available antiviral drugs, a considerable number of patients are facing an

dhpg
antiviral treatment
viral therapy
stem cell transplantation
antiviral drugs
  • 47 views
  • 21 Jan, 2021
  • 7 locations
Natural Killer Cell (CYNK-001) Infusions in Adults With AML

This study will find the maximum tolerated dose or the maximum planned dose of CYNK-001 which contains natural killer (NK) cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given after lymphodepleting chemotherapy. The safety of this treatment will be evaluated, and researchers want to learn …

immunosuppressive agents
remission
primary cancer
prednisone
cancer treatment
  • 43 views
  • 11 Mar, 2021
  • 7 locations
Study to Evaluate Induction of HBV Virus Neutralizing Antibodies Using VVX001

The Study will evaluate the effects of VVX001, a novel vaccine for hepatitis B, to elicit a robust protective IgG immune response in vaccine naive subjects in subjects who failed to demonstrate seroconversion after treatment with a licensed hepatitis B vaccine and in patients chronically infected with HBV.

hepatitis b antigen
hepatitis
vaccination
hepatitis b core antibody
  • 6 views
  • 12 Apr, 2021
  • 2 locations
Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

This phase II trial studies how well Triplex vaccine works in preventing cytomegalovirus (CMV) infection in patients undergoing a hematopoietic stem cell transplantation. CMV is a virus that may be carried for life and does not cause illness in most healthy individuals. However, in people whose immune systems are lowered …

immunosuppressive agents
vaccinia
multi-peptide cmv-modified vaccinia ankara vaccine
lymphoid leukemia
beta human chorionic gonadotropin
  • 4 views
  • 19 Jul, 2021
  • 1 location
Nebulised Dornase Alfa for Treatment of COVID-19

An open-label, randomised, Best-Available-Care (BAC) and historic-controlled trial of nebulised dornase alfa [2.5 mg BID] for 7 days in participants with COVID-19 who are admitted to hospital and are at risk of ventilatory failure (the COVASE study). Controls will include a randomised arm to receive BAC, historic data from UCLH …

coronavirus infection
dornase alfa inhalation solution [pulmozyme]
PCR test
oximetry
d-dimer
  • 0 views
  • 26 Jan, 2021
  • 1 location