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Found 19 clinical trials
Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)

(no treatment): Newly available and repurposed potential antiviral drugs; B: Positive control: monoclonal antibodies initially but subsequently any therapeutic that is shown to

  • 0 views
  • 07 Oct, 2022
  • 2 locations
Effect of Direct-acting Antiviral Drugs on Erectile Function

Effect of direct-acting antiviral drugs on erectile function

sofosbuvir
chronic hepatitis
daclatasvir
  • 38 views
  • 26 Feb, 2022
  • 1 location
Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation

This study is a randomized, prospective, comparative study of the effectiveness of prophylactic entecavir treatment for HBV reactivation in past HBV infected patients (HBsAg-, HBcIgG+) with hematopoietic stem cell transplantation.

hepatitis b core antibody
entecavir
  • 0 views
  • 26 Jul, 2021
  • 1 location
Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS) Incorporating Pilot Evaluation of KSHV Targeted Therapies

samples will be collected as well. People with KICS that requires treatment may get new experimental treatments. These treatments may include antiviral drugs and chemotherapy drugs, depending

fever
cancer
edema
lymphoma
imaging procedure
  • 81 views
  • 24 Oct, 2022
  • 1 location
Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS

-19. Additionally further trials and clinical observations have not found a significant benefit of other antiviral drugs. Although the results of several studies are still pending, there is still a

acute lung injury
coronavirus
pneumonia
SARS
acute respiratory distress
  • 0 views
  • 10 Jul, 2022
  • 2 locations
CMV Specific T Cell Therapy After Allogeneic Stem Cell Transplantation.

accompanied by an extremely high mortality rate and therefore the development of new treatment approaches is required. Despite the available antiviral drugs, a considerable number of patients are facing an

ganciclovir
cell transplantation
viremia
dhpg
antiviral drugs
  • 47 views
  • 24 Feb, 2022
  • 8 locations
Natural Killer Cell (CYNK-001) Infusions in Adults With AML (CYNK001AML01)

This study will find the maximum tolerated dose or the maximum planned dose of CYNK-001 which contains natural killer (NK) cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given after lymphodepleting chemotherapy. The safety of this treatment will be evaluated, and researchers want to learn …

blast cells
cancer
bilateral oophorectomy
treatment regimen
residual tumor
  • 43 views
  • 07 Oct, 2022
  • 7 locations
Chronic Hepatitis b Patients Switch to tAf After Discontinuation of Nucleoside Analogue

We will conduct a phase 4, multicenter, open-label trial at 7 academic centers in Taiwan. Chronic hepatitis B patients receiving oral antiviral therapy (entecavir [ETV], tenofovir disoproxil fumarate [TDF]) for at least 2 years, and fulfil the following nucleos(t)ide analogs discontinuation criteria. After nucleos(t)ide analogs discontinuation, patients had a clinical …

fumarate
antiviral therapy
tenofovir
hepatitis
entecavir
  • 0 views
  • 12 Aug, 2021
  • 7 locations
Study to Evaluate Induction of HBV Virus Neutralizing Antibodies Using VVX001

The Study will evaluate the effects of VVX001, a novel vaccine for hepatitis B, to elicit a robust protective IgG immune response in vaccine naive subjects in subjects who failed to demonstrate seroconversion after treatment with a licensed hepatitis B vaccine and in patients chronically infected with HBV.

hepatitis b core antibody
hepatitis b antigen
Accepts healthy volunteers
hepatitis
vaccination
  • 12 views
  • 12 Feb, 2022
  • 2 locations
Antiviral Therapy for Patients With Chronic Hepatitis B Infection

The study aims to demonstrate that antiviral therapy for patients with immune tolerance of CHB. On the basis of the original antiviral therapy of entecavir, further clarify the safety and effectiveness of entecavir combined with tenofovir amibufenamide.The investigators plan to enroll about 328 hepatitis B patients,. who are in the …

hepatitis
tenofovir
antiviral therapy
entecavir
  • 0 views
  • 08 Jun, 2022
  • 1 location