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Found 20 clinical trials
Switching Regimen in Treating Cirrhotic HCV GT1b Subjects

This is a prospective, randomized study to evaluate the efficacy and safety of switching treatment from Peg-interferon and Ribavirin to direct-acting antiviral agents in Chinese with CHC

  • 15 views
  • 09 Sep, 2021
  • 2 locations
Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides

Both tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) are potent antiviral agents for hepatitis B virus (HBV) and recommended by the American Association for the Study of

lamivudine
entecavir
fumarate
antiviral therapy
antiviral drugs
  • 0 views
  • 21 Feb, 2022
  • 10 locations
Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis Post HSCT

, immunosuppressant reduction, and platelet transfusion. Patients with viral infection may be treated with antiviral agents, but their efficacy is limited. When the HC was considered to be associated with aGVHD, some

cell transplantation
clot formation
acute graft-versus-host disease
hemorrhagic cystitis
tissue damage
  • 1 views
  • 18 Sep, 2021
  • 1 location
Chinese Medicine for Patients With LCOVID-19 Symptoms

COVID-19 has spread rapidly and now affects all over the world. On 11 March 2020, coronavirus disease 2019 (COVID-19) was declared a global pandemic by the World Health Organization (WHO). Most of the infected people will develop mild to moderate illness, for example fever, cough, tiredness and joint pain etc. …

  • 2 views
  • 21 Mar, 2022
  • 1 location
People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

Background Chronic hepatitis C infects the liver. It may scar the liver. This is called cirrhosis and may lead to liver cancer or death. Current chronic hepatitis C treatments cure most people. But some keep getting complications even after it is cured. Researchers want to study why. Objective To study …

cirrhosis
hcv genotype
fibroscan
antiviral drugs
hemoglobin a1c
  • 23 views
  • 07 Oct, 2022
  • 1 location
Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation

This study is a randomized, prospective, comparative study of the effectiveness of prophylactic entecavir treatment for HBV reactivation in past HBV infected patients (HBsAg-, HBcIgG+) with hematopoietic stem cell transplantation.

entecavir
hepatitis b core antibody
  • 0 views
  • 26 Jul, 2021
  • 1 location
Tenofovir Alafenamide in HBV Related Decompensated Liver

subjects with CPT scores 7, either at time of screening or by history, who were virally suppressed on TDF and/or other oral antiviral agents is currently underway with favorable safety and efficacy results

  • 42 views
  • 27 Jan, 2021
  • 1 location
Natural Killer Cell (CYNK-001) Infusions in Adults With AML (CYNK001AML01)

This study will find the maximum tolerated dose or the maximum planned dose of CYNK-001 which contains natural killer (NK) cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given after lymphodepleting chemotherapy. The safety of this treatment will be evaluated, and researchers want to learn …

cell transplantation
residual tumor
cancer
leukemia
immunosuppressant
  • 43 views
  • 07 Oct, 2022
  • 7 locations
Chronic Hepatitis b Patients Switch to tAf After Discontinuation of Nucleoside Analogue

We will conduct a phase 4, multicenter, open-label trial at 7 academic centers in Taiwan. Chronic hepatitis B patients receiving oral antiviral therapy (entecavir [ETV], tenofovir disoproxil fumarate [TDF]) for at least 2 years, and fulfil the following nucleos(t)ide analogs discontinuation criteria. After nucleos(t)ide analogs discontinuation, patients had a clinical …

entecavir
fumarate
antiviral therapy
tenofovir
hepatitis
  • 0 views
  • 12 Aug, 2021
  • 7 locations
Influenza Human Challenge Model

This study examines how the immune system responds to the flu virus (H3N2) during and after infection and how the flu virus is transmitted in the environment. The study will used a flu virus called the H3N2 influenza challenge virus which was produced specifically for use in clinical research in …

baloxavir marboxil
peramivir
immunosuppression
Accepts healthy volunteers
cancer
  • 0 views
  • 10 Jul, 2022
  • 3 locations