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Found 31 clinical trials
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Switching Regimen in Treating Cirrhotic HCV GT1b Subjects

This is a prospective, randomized study to evaluate the efficacy and safety of switching treatment from Peg-interferon and Ribavirin to direct-acting antiviral agents in Chinese with CHC

  • 15 views
  • 09 Sep, 2021
  • 2 locations
None
Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides

Both tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) are potent antiviral agents for hepatitis B virus (HBV) and recommended by the American Association for the Study of

antiviral therapy
fumarate
liver disease
chronic hepatitis
entecavir
  • 0 views
  • 26 Jan, 2021
  • 10 locations
None
Assessment of Efficacy of KAN-JANG in Mild COVID-19

The complexity of COVID-19 suggests a potential need for a range of therapies, including antiviral agents, immunostimulants, immunosuppressants, adaptogens, and anticoagulants. In this context

  • 0 views
  • 01 Oct, 2021
  • 1 location
None
Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis Post HSCT

, immunosuppressant reduction, and platelet transfusion. Patients with viral infection may be treated with antiviral agents, but their efficacy is limited. When the HC was considered to be associated with aGVHD, some

antiviral agents
hemorrhagic cystitis
tissue damage
acute graft-versus-host disease
graft versus host disease
  • 1 views
  • 18 Sep, 2021
  • 1 location
None
Changes in Liver Fibrosis Lipid Profile and Insulin Resistance in HCV Patients Who Received Antiviral Therapy

Hepatitis C virus (HCV) is one of the major globally cause of death and morbidity.Chronic hepatitis C is the leading cause of end-stage liver disease, hepatocellular carcinoma and liver-related death in Egypt.It could be considered a special type of metabolic diseases involving insulin resistance (IR) which accelerates fibrosis and modulation …

antiviral therapy
diabetes
daclatasvir
ribavirin
hepatic fibrosis
  • 39 views
  • 25 Jan, 2021
  • 1 location
None
Antiviral Agents Against COVID-19 Infection

A key strategy in the treatment of COVID-19 would be to find an effective antiviral agent that would decrease the peak viral load and, consequently, the associated degree of immunopathological damage that follows this phase. The clinically approved substances considered for this study are used for treatment of other virus …

  • 0 views
  • 11 Nov, 2021
  • 1 location
None
People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

Background Chronic hepatitis C infects the liver. It may scar the liver. This is called cirrhosis and may lead to liver cancer or death. Current chronic hepatitis C treatments cure most people. But some keep getting complications even after it is cured. Researchers want to study why. Objective To study …

ribavirin
hemoglobin a1c
cancer
hemophilia
liver disease
  • 18 views
  • 28 Nov, 2021
  • 1 location
None
Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation

This study is a randomized, prospective, comparative study of the effectiveness of prophylactic entecavir treatment for HBV reactivation in past HBV infected patients (HBsAg-, HBcIgG+) with hematopoietic stem cell transplantation.

entecavir
hepatitis b core antibody
  • 0 views
  • 26 Jul, 2021
  • 1 location
None
COVID-19 Ozanimod Intervention Study

antiviral agents. Ozanimod was approved by the FDA for the treatment of relapsing multiple sclerosis at the end of March 2020, and was recently (October 2020) approved by Health Canada for the same

pneumonia
PCR test
FIO2
acute respiratory distress
SARS
  • 0 views
  • 08 Jun, 2021
  • 2 locations
None
Tenofovir Alafenamide in HBV Related Decompensated Liver

subjects with CPT scores 7, either at time of screening or by history, who were virally suppressed on TDF and/or other oral antiviral agents is currently underway with favorable safety and efficacy results

  • 8 views
  • 27 Jan, 2021
  • 1 location