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Found 15 clinical trials
Antithymocyte Globulin as a Second Line Therapy in Graves Orbitopathy

The overall objective of the study is to evaluate the safety and efficacy of rabbit antithymocyte globulin in the treatment of Graves orbitopathy (GO) after ineffective treatment with moderate

  • 0 views
  • 25 Mar, 2022
Impact of Optimal Doses of Antithymocyte Globulin Conditioning on Graft Versus-host Disease and Virus Reactivation in Haploidentical Hematopoietic Stem Cell Transplantation

The purpose of this study is to determine the response and toxicity rate of two different dosages (Individualized dosage VS. fixed dosage) of ATG as a prophylaxis for acute GVHD in haploidentical peripheral blood stem cell transplantation (haplo-PBSCT).

  • 0 views
  • 15 Oct, 2022
  • 1 location
Antithymocyte Globulin and Azathioprine Versus Basiliximab and Mycophenolate Mofetil in Living Donor Kidney Transplantation

to compare the efficiency and cost of two immunosuppressive protocols after living donor kidney transplantation: (1) antithymocyte globulin, tacrolimus, azathioprine and prednisolone versus (2

  • 2 views
  • 22 Jan, 2021
  • 1 location
  • 0 views
  • 16 Apr, 2021
  • 1 location
Autologous Peripheral Blood Stem Cell Transplant for Neurologic Autoimmune Diseases

This phase II trial studies the side effects and how well carmustine, etoposide, cytarabine and melphalan together with antithymocyte globulin before a peripheral blood stem cell transplant

multiple sclerosis
blood stem cell transplant
paraparesis
white blood cell count
cerebellar degeneration
  • 214 views
  • 11 Jul, 2022
  • 3 locations
A Pilot Study of Condensed Busulfan, Melphalan, and Fludarabine Conditioning Prior to Ex-vivo CD34+ Selected Allogeneic Hematopoietic Cell Transplantation

The purpose of this study is to see if a condensed version of the chemotherapy regimen busulfan, melphalan, fludarabine (bu/mel/flu) and the drug antithymocyte globulin (ATG-also referred to as

chronic myelomonocytic leukemia
acute leukemia
lymphoid leukemia
busulfan
cell transplantation
  • 5 views
  • 27 Oct, 2022
  • 1 location
ATG in HLA-matched Sibling HSCT as GVHD Prophylaxis

antithymocyte globulin (ATG) could reduce the incidence of cGVHD. This study is aim to evaluate the efficacy of a protocol that includes CsA, MTX, MMF and ATG in recipients of MSD HSCT.

mycophenolate mofetil
methotrexate
graft versus host disease
allogeneic hematopoietic stem cell transplant
  • 0 views
  • 21 Feb, 2022
  • 1 location
Hematopoietic Cell Transplantation Using Treosulfan-Based Conditioning for the Treatment of Bone Marrow Failure Diseases

This phase II trial tests whether treosulfan, fludarabine, and rabbit antithymocyte globulin (rATG) work when given before a blood or bone marrow transplant (conditioning regimen) to cause fewer

hemolysis
cell transplantation
stem cell transplantation
anemia
cancer
  • 0 views
  • 22 Oct, 2022
  • 17 locations
Ixazomib in the Prophylaxis of Chronic Graft-versus-host Disease.

Allogeneic hematopoietic stem cell transplantation (HTC) is the only curative option for many patients with hematologic malignancies but >50% of this patients will develop extensive chronic graft-versus-host disease (cGVHD), which remains the most important complication after HTC. Classically, the most effective strategies to prevent GVHD have not improved survival; therefore, …

absolute neutrophil count
cyclophosphamide
platelet count
cell transplantation
neutrophil count
  • 2 views
  • 03 Jun, 2022
  • 4 locations
ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors

ATG based conditioning regimen in HLA related allogeneic hematopoietic stem cell transplantation for aggressive T-cell tumors: multi-center, open, randomized controlled clinical study

  • 0 views
  • 21 Jan, 2021
  • 1 location